DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15436 and ZNF577

DIOPT Version :9

Sequence 1:NP_608840.1 Gene:CG15436 / 33657 FlyBaseID:FBgn0031610 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_001357376.1 Gene:ZNF577 / 84765 HGNCID:28673 Length:485 Species:Homo sapiens


Alignment Length:227 Identity:86/227 - (37%)
Similarity:128/227 - (56%) Gaps:5/227 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 SDSKKVA-----FECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNA 178
            :|.:|:.     .||..|.:.:.||...::|.||....:...|..|.:.|..::.|..|.:||..
Human   146 NDLQKICAGGKPHECSVCGRAFSRKAQLIQHQRTERGEKPHGCGECGKTFMRKIQLTEHQRTHTG 210

  Fly   179 AKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKC 243
            .||:|||.|.|.|:::|.|..|:||||||:|::||:|.|.|.:...|.||.|:|..|:.:.||.|
Human   211 EKPHECSECGKAFSRKSQLMVHQRTHTGEKPYRCSKCGKAFSRKCRLNRHQRSHTGEKLYGCSVC 275

  Fly   244 TKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSST 308
            .|.|::|.:|..|.|.|||::|:|||.|.:.|..|..|.:|.|:|..::|:.||.|.|.||..|.
Human   276 GKAFSQKAYLTAHQRLHTGDKPYKCSDCGRTFYFKSDLTRHQRIHTGEKPYECSECEKAFRSKSK 340

  Fly   309 LKEHKLVHNAERTFKCPHCASFYKQRKTLARH 340
            |.:|:..|..||.:.|..|...:.....|.:|
Human   341 LIQHQRTHTGERPYSCRECGKAFAHMSVLIKH 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15436NP_608840.1 zf-AD 4..78 CDD:285071
C2H2 Zn finger 128..148 CDD:275368 6/19 (32%)
C2H2 Zn finger 156..176 CDD:275368 5/19 (26%)
COG5048 <180..341 CDD:227381 69/161 (43%)
C2H2 Zn finger 184..204 CDD:275368 9/19 (47%)
zf-H2C2_2 197..219 CDD:290200 13/21 (62%)
C2H2 Zn finger 212..232 CDD:275368 9/19 (47%)
zf-H2C2_2 224..249 CDD:290200 11/24 (46%)
C2H2 Zn finger 240..260 CDD:275368 9/19 (47%)
zf-H2C2_2 252..276 CDD:290200 11/23 (48%)
C2H2 Zn finger 268..288 CDD:275368 8/19 (42%)
C2H2 Zn finger 296..316 CDD:275368 9/19 (47%)
C2H2 Zn finger 324..341 CDD:275368 4/17 (24%)
ZNF577NP_001357376.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
KRAB 25..83 CDD:214630
COG5048 136..>217 CDD:227381 20/70 (29%)
C2H2 Zn finger 160..180 CDD:275368 6/19 (32%)
C2H2 Zn finger 188..208 CDD:275368 5/19 (26%)
COG5048 <194..399 CDD:227381 74/179 (41%)
C2H2 Zn finger 216..236 CDD:275368 9/19 (47%)
C2H2 Zn finger 244..264 CDD:275368 9/19 (47%)
C2H2 Zn finger 272..292 CDD:275368 9/19 (47%)
C2H2 Zn finger 300..320 CDD:275368 8/19 (42%)
C2H2 Zn finger 328..348 CDD:275368 9/19 (47%)
C2H2 Zn finger 356..376 CDD:275368 4/17 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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