DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15436 and ZNF154

DIOPT Version :9

Sequence 1:NP_608840.1 Gene:CG15436 / 33657 FlyBaseID:FBgn0031610 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_001078853.1 Gene:ZNF154 / 7710 HGNCID:12939 Length:437 Species:Homo sapiens


Alignment Length:237 Identity:92/237 - (38%)
Similarity:134/237 - (56%) Gaps:13/237 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 GKSDSKKVA-------------FECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVT 168
            |||.||..:             :|||||.|.:::..:.::|.|.|...:...|..|.:.|..:..
Human   167 GKSFSKSYSLNDHWRLHTGEKPYECRECGKSFRQSSSLIQHRRVHTAVRPHECDECGKLFSNKSN 231

  Fly   169 LKAHMKTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHG 233
            |..|.:.|...:|||||.|.|:|:|:|.|..|...||||||::||:|.|.|...|.|.:|.:.|.
Human   232 LIKHRRVHTGERPYECSECGKSFSQRSALLQHRGVHTGERPYECSECGKFFTYHSSLIKHQKVHS 296

  Fly   234 SERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSH 298
            ..||::||:|.|:|::...|..|.|.||||||:|||.|.|:|:.:..|.||..:|..:||:.||.
Human   297 GSRPYECSECGKSFSQNSSLIEHHRVHTGERPYKCSECGKSFSQRSALLQHRGVHTGERPYECSE 361

  Fly   299 CPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTLARH 340
            |.|.|..||:|::|:.||...|.::|..|...:.|...|.:|
Human   362 CGKFFPYSSSLRKHQRVHTGSRPYECSECGKSFTQNSGLIKH 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15436NP_608840.1 zf-AD 4..78 CDD:285071
C2H2 Zn finger 128..148 CDD:275368 7/19 (37%)
C2H2 Zn finger 156..176 CDD:275368 5/19 (26%)
COG5048 <180..341 CDD:227381 72/161 (45%)
C2H2 Zn finger 184..204 CDD:275368 9/19 (47%)
zf-H2C2_2 197..219 CDD:290200 12/21 (57%)
C2H2 Zn finger 212..232 CDD:275368 8/19 (42%)
zf-H2C2_2 224..249 CDD:290200 10/24 (42%)
C2H2 Zn finger 240..260 CDD:275368 8/19 (42%)
zf-H2C2_2 252..276 CDD:290200 14/23 (61%)
C2H2 Zn finger 268..288 CDD:275368 8/19 (42%)
C2H2 Zn finger 296..316 CDD:275368 9/19 (47%)
C2H2 Zn finger 324..341 CDD:275368 5/17 (29%)
ZNF154NP_001078853.1 KRAB 14..>62 CDD:214630
KRAB 14..53 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 110..129
C2H2 Zn finger 135..155 CDD:275368
COG5048 139..>436 CDD:227381 92/237 (39%)
C2H2 Zn finger 163..183 CDD:275368 5/15 (33%)
C2H2 Zn finger 191..211 CDD:275368 7/19 (37%)
C2H2 Zn finger 219..239 CDD:275368 5/19 (26%)
zf-H2C2_2 231..256 CDD:290200 11/24 (46%)
C2H2 Zn finger 247..267 CDD:275368 9/19 (47%)
C2H2 Zn finger 275..295 CDD:275368 8/19 (42%)
zf-H2C2_2 287..312 CDD:290200 10/24 (42%)
C2H2 Zn finger 303..323 CDD:275368 8/19 (42%)
zf-H2C2_2 315..340 CDD:290200 15/24 (63%)
C2H2 Zn finger 331..351 CDD:275368 8/19 (42%)
C2H2 Zn finger 359..379 CDD:275368 9/19 (47%)
zf-H2C2_2 371..396 CDD:290200 7/24 (29%)
C2H2 Zn finger 387..407 CDD:275368 5/17 (29%)
zf-H2C2_2 400..424 CDD:290200 2/4 (50%)
C2H2 Zn finger 415..435 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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