Protein Alignment CG15436 and ZNF16

DIOPT Version :9

• Sequence 1: NP_608840.1
• Gene: CG15436 / 33657
• FlyBaseID: FBgn0031610
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: NP_001025147.2
• Gene: ZNF16 / 7564
• HGNCID: 12947
• Length: 682
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 89/232 - (38%)
• Similarity: 132/232 - (56%)
• Gaps: 8/232 - (3%)

  Fly   117 GKSD--------SKKVAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHM 173
            |.||        |.:..:.|.||.|.:.:..:..:|.::||..:.:.|..|.:.||....|..|.
Human   276 GHSDFSRHQSHHSSERPYMCNECGKAFSQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQ 340

  Fly   174 KTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPF 238
            :.|:..|||.||.|.|.|.:.|.|..|.||||||:||:|.:|.|.|.:|:.||:|.|.|..|:|:
Human   341 RIHSGEKPYVCSECGKAFRRSSNLIKHHRTHTGEKPFECGECGKAFSQSAHLRKHQRVHTGEKPY 405

  Fly   239 KCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTF 303
            :|:.|.|.|:|..:|..|.|.||||:|:|||.|.|||:....|.||.|:|..::|..|:.|.|.|
Human   406 ECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGKAF 470

  Fly   304 RLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTLARH 340
            ..||.|::|:::|..|:.::|..|...:.....|.:|
Human   471 SYSSVLRKHQIIHTGEKPYRCSVCGKAFSHSSALIQH 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071
		C2H2 Zn finger	128..148	CDD:275368	5/19 (26%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	<180..341	CDD:227381	71/161 (44%)
		C2H2 Zn finger	184..204	CDD:275368	9/19 (47%)
		zf-H2C2_2	197..219	CDD:290200	13/21 (62%)
		C2H2 Zn finger	212..232	CDD:275368	9/19 (47%)
		zf-H2C2_2	224..249	CDD:290200	11/24 (46%)
		C2H2 Zn finger	240..260	CDD:275368	8/19 (42%)
		zf-H2C2_2	252..276	CDD:290200	14/23 (61%)
		C2H2 Zn finger	268..288	CDD:275368	10/19 (53%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		C2H2 Zn finger	324..341	CDD:275368	4/17 (24%)
ZNF16	NP_001025147.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Necessary for transcription activation	62..210
		COG5048	<160..369	CDD:227381	29/92 (32%)
		C2H2 Zn finger	187..203	CDD:275368
		C2H2 Zn finger	211..231	CDD:275368
		C2H2 Zn finger	239..259	CDD:275368
		C2H2 Zn finger	267..287	CDD:275368	3/10 (30%)
		Required for nuclear localization	268..393		42/116 (36%)
		C2H2 Zn finger	295..315	CDD:275368	5/19 (26%)
		COG5048	303..675	CDD:227381	81/205 (40%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		Required for nuclear localization	341..373		15/31 (48%)
		C2H2 Zn finger	351..371	CDD:275368	9/19 (47%)
		C2H2 Zn finger	379..399	CDD:275368	9/19 (47%)
		C2H2 Zn finger	407..427	CDD:275368	8/19 (42%)
		C2H2 Zn finger	435..455	CDD:275368	10/19 (53%)
		C2H2 Zn finger	463..483	CDD:275368	8/19 (42%)
		Required for nuclear localization	473..503		8/29 (28%)
		C2H2 Zn finger	491..511	CDD:275368	4/17 (24%)
		C2H2 Zn finger	519..539	CDD:275368
		C2H2 Zn finger	547..567	CDD:275368
		C2H2 Zn finger	575..595	CDD:275368
		C2H2 Zn finger	603..623	CDD:275368
		C2H2 Zn finger	631..651	CDD:275368
		C2H2 Zn finger	659..679	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910