DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15436 and Sry-beta

DIOPT Version :9

Sequence 1:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	74/314 - (23%)
Similarity:	120/314 - (38%)	Gaps:	71/314 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CMDISGKLVNIFDARRRTRVSI-AEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIRQTCEE 71
            |..:.||......|.:|.||.: |..|.|.|..                 ::.:...|....|||
  Fly    90 CRQVEGKAETKQQAAKRARVQVPAFKIVQATAL-----------------KEPERQPGEEDECEE 137

  Fly    72 SHQFYCRVRDEGIEDALCALLEEEDWEISEDEDARIDSASAADDDGKSDSKKVAFECRECHKKYQ 136
            .      :::|        :|:|| ::.||.:    ||..:::::..:::.::
  Fly   138 F------MKEE--------MLDEE-FQFSEPD----DSMPSSEEEFFTETTEI------------ 171

  Fly   137 RKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYE--CSHCAKTFAQQSTLQS 199
                              ||..|...|..:..|:.|:|.....|..:  |:.|.........|..
  Fly   172 ------------------PCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDL 218

  Fly   200 HERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFRSHTG-E 263
            |...|.|:...:|..|.|.|....::.||:..|..::.::|.||.:.|:..:.:.||...|.. |
  Fly   219 HMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEE 283

  Fly   264 RPFKCSHCPKAFAMKQHLKQHSRLHLPDRP-FRCSHCPKTFRLSSTLKEHKLVH 316
            ....|..|.:.|..|:..|.|.|.|..||| :.|..|.|:|....|||.||.||
  Fly   284 NALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVH 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	15/70 (21%)
		C2H2 Zn finger	128..148	CDD:275368	0/19 (0%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	<180..341	CDD:227381	44/141 (31%)
		C2H2 Zn finger	184..204	CDD:275368	4/19 (21%)
		zf-H2C2_2	197..219	CDD:290200	7/21 (33%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		zf-H2C2_2	224..249	CDD:290200	7/24 (29%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-H2C2_2	252..276	CDD:290200	6/24 (25%)
		C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		C2H2 Zn finger	296..316	CDD:275368	9/19 (47%)
		C2H2 Zn finger	324..341	CDD:275368
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	4/19 (21%)
		C2H2 Zn finger	231..251	CDD:275368	6/19 (32%)
		C2H2 Zn finger	259..308	CDD:275368	15/48 (31%)
		C2H2 Zn finger	288..303	CDD:275370	4/14 (29%)
		zf-C2H2	315..337	CDD:278523	9/21 (43%)
		C2H2 Zn finger	317..337	CDD:275368	9/19 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930