DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15436 and ZNF404

DIOPT Version :9

Sequence 1:NP_608840.1 Gene:CG15436 / 33657 FlyBaseID:FBgn0031610 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_001028891.2 Gene:ZNF404 / 342908 HGNCID:19417 Length:552 Species:Homo sapiens


Alignment Length:215 Identity:77/215 - (35%)
Similarity:118/215 - (54%) Gaps:0/215 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   126 FECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSHCAKT 190
            :||::|.|.::|......|.:.|:..:.|.|..|...|||...:..|.|.|:..|||:|..|.|.
Human   215 YECKQCGKAFRRHSHLTEHQKIHVGLKPFECKECGETFRLYRHMCLHQKIHHGVKPYKCKECGKA 279

  Fly   191 FAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDN 255
            |..:|:|..|::.|:||:|:||.||.|.|::|..|..|.|:|..|:|.:|.:|.|.|.:...|..
Human   280 FGHRSSLYQHKKIHSGEKPYKCEQCEKAFVRSYLLVEHQRSHTGEKPHECMECGKAFGKGSSLLK 344

  Fly   256 HFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAER 320
            |.|.|:.|:.:.|..|.|||.....|.||.|:|..::|..|..|.|||:|.|.|.:|:::|...:
Human   345 HKRIHSSEKLYDCKDCGKAFCRGSQLTQHQRIHTGEKPHECKECGKTFKLHSYLIQHQIIHTDLK 409

  Fly   321 TFKCPHCASFYKQRKTLARH 340
            .::|..|...:.:...|..|
Human   410 PYECKQCGKAFSRVGDLKTH 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15436NP_608840.1 zf-AD 4..78 CDD:285071
C2H2 Zn finger 128..148 CDD:275368 5/19 (26%)
C2H2 Zn finger 156..176 CDD:275368 7/19 (37%)
COG5048 <180..341 CDD:227381 61/161 (38%)
C2H2 Zn finger 184..204 CDD:275368 7/19 (37%)
zf-H2C2_2 197..219 CDD:290200 11/21 (52%)
C2H2 Zn finger 212..232 CDD:275368 9/19 (47%)
zf-H2C2_2 224..249 CDD:290200 10/24 (42%)
C2H2 Zn finger 240..260 CDD:275368 7/19 (37%)
zf-H2C2_2 252..276 CDD:290200 9/23 (39%)
C2H2 Zn finger 268..288 CDD:275368 9/19 (47%)
C2H2 Zn finger 296..316 CDD:275368 9/19 (47%)
C2H2 Zn finger 324..341 CDD:275368 4/17 (24%)
ZNF404NP_001028891.2 KRAB 6..>51 CDD:214630
KRAB 6..45 CDD:279668
COG5048 106..510 CDD:227381 77/215 (36%)
C2H2 Zn finger 133..153 CDD:275368
C2H2 Zn finger 161..181 CDD:275368
C2H2 Zn finger 189..209 CDD:275368
C2H2 Zn finger 217..237 CDD:275368 5/19 (26%)
C2H2 Zn finger 245..265 CDD:275368 7/19 (37%)
C2H2 Zn finger 273..293 CDD:275368 7/19 (37%)
zf-H2C2_2 285..310 CDD:290200 12/24 (50%)
C2H2 Zn finger 301..321 CDD:275368 9/19 (47%)
zf-H2C2_2 314..336 CDD:290200 9/21 (43%)
C2H2 Zn finger 329..349 CDD:275368 7/19 (37%)
C2H2 Zn finger 357..377 CDD:275368 9/19 (47%)
zf-H2C2_2 370..393 CDD:290200 10/22 (45%)
C2H2 Zn finger 385..405 CDD:275368 9/19 (47%)
CpXC 413..>458 CDD:291051 4/17 (24%)
C2H2 Zn finger 413..433 CDD:275368 4/17 (24%)
C2H2 Zn finger 441..461 CDD:275368
C2H2 Zn finger 469..489 CDD:275368
zf-H2C2_2 482..506 CDD:290200
C2H2 Zn finger 497..517 CDD:275368
C2H2 Zn finger 525..545 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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