Protein Alignment CG15436 and ZNF680

DIOPT Version :9

• Sequence 1: NP_608840.1
• Gene: CG15436 / 33657
• FlyBaseID: FBgn0031610
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: NP_848653.2
• Gene: ZNF680 / 340252
• HGNCID: 26897
• Length: 530
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 82/215 - (38%)
• Similarity: 122/215 - (56%)
• Gaps: 0/215 - (0%)

  Fly   126 FECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSHCAKT 190
            ::|.||.|.:.:..|.::|.:.|::.:.|.|..|.:.|.|...|..|...|...|||:|..|.|.
Human   238 YKCEECGKAFNQSSTLIKHKKIHIEEKPFKCEECGKAFSLFSILSKHKIIHTGDKPYKCDECHKA 302

  Fly   191 FAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDN 255
            |...:||.:|:|.||||:||||.:|.|.|.:.|:|.:|.:.|..|:|:||.:|.|.|.:..:|..
Human   303 FNWFATLTNHKRIHTGEKPFKCEECGKDFNQFSNLTKHKKIHTGEKPYKCEECGKAFNQFANLTR 367

  Fly   256 HFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAER 320
            |.:.||||:.:||..|.|||....:|.:|.|:|..::|::|..|.|.|...|:|..||.:|..|.
Human   368 HKKIHTGEKSYKCEECGKAFIQSSNLTEHMRIHTGEKPYKCEECGKAFNGCSSLTRHKRIHTREN 432

  Fly   321 TFKCPHCASFYKQRKTLARH 340
            |:||..|...:....||..|
Human   433 TYKCEECGKGFTLFSTLTNH 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071
		C2H2 Zn finger	128..148	CDD:275368	6/19 (32%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	<180..341	CDD:227381	67/161 (42%)
		C2H2 Zn finger	184..204	CDD:275368	8/19 (42%)
		zf-H2C2_2	197..219	CDD:290200	13/21 (62%)
		C2H2 Zn finger	212..232	CDD:275368	7/19 (37%)
		zf-H2C2_2	224..249	CDD:290200	10/24 (42%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-H2C2_2	252..276	CDD:290200	11/23 (48%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		C2H2 Zn finger	324..341	CDD:275368	5/17 (29%)
ZNF680	NP_848653.2	KRAB	13..73	CDD:214630
		KRAB	13..52	CDD:279668
		COG5048	152..513	CDD:227381	82/215 (38%)
		zf-C2H2	182..204	CDD:278523
		C2H2 Zn finger	184..204	CDD:275368
		C2H2 Zn finger	212..232	CDD:275368
		zf-H2C2_2	224..249	CDD:290200	4/10 (40%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-H2C2_2	253..276	CDD:290200	5/22 (23%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		zf-H2C2_2	281..304	CDD:290200	9/22 (41%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		zf-H2C2_2	309..333	CDD:290200	14/23 (61%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		zf-H2C2_2	336..361	CDD:290200	10/24 (42%)
		C2H2 Zn finger	352..372	CDD:275368	6/19 (32%)
		zf-H2C2_2	364..389	CDD:290200	12/24 (50%)
		C2H2 Zn finger	380..400	CDD:275368	8/19 (42%)
		zf-H2C2_2	392..416	CDD:290200	8/23 (35%)
		C2H2 Zn finger	408..428	CDD:275368	8/19 (42%)
		C2H2 Zn finger	436..456	CDD:275368	5/17 (29%)
		C2H2 Zn finger	464..484	CDD:275368
		zf-H2C2_2	477..501	CDD:290200
		zf-C2H2	490..512	CDD:278523
		C2H2 Zn finger	492..512	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910