DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15436 and CG2129

DIOPT Version :9

Sequence 1:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	325	Identity:	96/325 - (29%)
Similarity:	137/325 - (42%)	Gaps:	49/325 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 QCTGFEVKRGDLFSE--------MICPQCYEDVKSAYGIRQTCEESHQFYCRVRDEGIEDALCAL 91
            :| |.|:   ||.||        ..||.|.:..:|...:.:.....|           :|.|...
  Fly   162 EC-GMEL---DLDSEGRHSAKIPHSCPHCTKVYQSRKVLERHIMRQH-----------KDTLSPD 211

  Fly    92 LEEEDWEISEDEDARIDSASAADDDGKSDSKKVAFECRECHKKYQRKGTFLRHM-RTHMDGQS-- 153
            ::.||.:....:||.:.||:.            .::|..|.|.|..|.:..:|: |.|.:|:.
  Fly   212 VDSEDADYEPPKDAPVKSAAQ------------EYKCEHCGKIYHGKYSLRQHLKRDHDNGEEGG 264

  Fly   154 ---FPCPYCKRNF-RLRVTLKAHM-KTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCS 213
               |.|..|:... |||: |..|| :.|..|   .|..|.:.:..:..|:.|:..||.||...|.
  Fly   265 SAIFTCLECEAQLPRLRL-LDEHMVQAHGGA---ACVVCGRRYKTRHELKRHQLKHTSERNVPCP 325

  Fly   214 Q--CSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFA 276
            .  |.|.|.....:|.|.:.|..::.|.|..|..:...|..|..|.|||||||||.|..|.|.|.
  Fly   326 HPGCGKRFFTIRHMRNHGKVHTEQKNFVCESCGYSCRNKETLRVHIRSHTGERPFGCQVCDKRFP 390

  Fly   277 MKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTLARHI 341
            ....|::|..:|..:||..||.|..||.....|..||.:|...:.|.|..|.:.|.|...||.|:
  Fly   391 SHSGLREHMAMHSTERPHVCSVCGATFSRQKGLYHHKFLHADTKQFVCKLCGNAYAQAAGLAGHM 455

Fly 342 341
Fly 456 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	12/50 (24%)
		C2H2 Zn finger	128..148	CDD:275368	7/20 (35%)
		C2H2 Zn finger	156..176	CDD:275368	8/21 (38%)
		COG5048	<180..341	CDD:227381	55/162 (34%)
		C2H2 Zn finger	184..204	CDD:275368	4/19 (21%)
		zf-H2C2_2	197..219	CDD:290200	9/23 (39%)
		C2H2 Zn finger	212..232	CDD:275368	6/21 (29%)
		zf-H2C2_2	224..249	CDD:290200	6/24 (25%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-H2C2_2	252..276	CDD:290200	14/23 (61%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		C2H2 Zn finger	324..341	CDD:275368	6/16 (38%)
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	4/19 (21%)
		zf-C2H2_8	323..411	CDD:292531	31/87 (36%)
		C2H2 Zn finger	327..346	CDD:275368	5/18 (28%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	367..389	CDD:290200	14/21 (67%)
		C2H2 Zn finger	382..402	CDD:275368	6/19 (32%)
		zf-H2C2_2	395..419	CDD:290200	10/23 (43%)
		C2H2 Zn finger	410..430	CDD:275368	8/19 (42%)
		C2H2 Zn finger	438..458	CDD:275368	7/18 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100