DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15436 and CG2120

DIOPT Version :9

Sequence 1:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	334	Identity:	87/334 - (26%)
Similarity:	133/334 - (39%)	Gaps:	56/334 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DLFSEMICPQCYEDVKSAYGIRQTCEESHQFYCRVRD---EGIEDALCALLEEEDWEISEDEDAR 106
            |..|:|......:|....|.:   |.|..|.:.::.|   |.:...:..|....::::.|..:..
  Fly     5 DPVSQMANATLADDDLGNYDV---CLEDLQLFAQLEDLSGERLPMEMELLNPGSEYDLLELVNGA 66

  Fly   107 IDSASAADDDGKSDSKKVAFECRECHK-----KYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLR 166
            :...:..:                 ||     |.:|..|..||..|   |:...|..|.|.|...
  Fly    67 LQQRNTTE-----------------HKPTDMCKPKRTPTTKRHRTT---GKDHTCDICDRRFSEA 111

  Fly   167 VTLKAHMKTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRT 231
            ..|:.|..||...||:.|..|.|.|.|.:.|:.|..|||.|||.||..|.|.|..::.|..|.|.
  Fly   112 YNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRL 176

  Fly   232 HGSERPFKC--SKCTKTF----TRKFHLDNHFRSHTGERP----------------FKCSHCPKA 274
            |..|:|:.|  :.|..:|    .|:.|......:.|...|                |.|..|.:.
  Fly   177 HTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRV 241

  Fly   275 FAMKQHLKQHSRLHLPDRPFRC--SHCPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTL 337
            ...:.:|..|.:.|...|.|.|  ..|.|.|..:|.||.|::.|..:|.|.||.|.:.:.::...
  Fly   242 LTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNH 306

  Fly   338 ARHILEIHK 346
            .:| |::|:
  Fly   307 KQH-LKVHE 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	8/32 (25%)
		C2H2 Zn finger	128..148	CDD:275368	7/24 (29%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	<180..341	CDD:227381	55/184 (30%)
		C2H2 Zn finger	184..204	CDD:275368	7/19 (37%)
		zf-H2C2_2	197..219	CDD:290200	12/21 (57%)
		C2H2 Zn finger	212..232	CDD:275368	7/19 (37%)
		zf-H2C2_2	224..249	CDD:290200	9/30 (30%)
		C2H2 Zn finger	240..260	CDD:275368	5/25 (20%)
		zf-H2C2_2	252..276	CDD:290200	6/39 (15%)
		C2H2 Zn finger	268..288	CDD:275368	4/19 (21%)
		C2H2 Zn finger	296..316	CDD:275368	8/21 (38%)
		C2H2 Zn finger	324..341	CDD:275368	3/16 (19%)
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	6/19 (32%)
		zf-H2C2_2	113..138	CDD:290200	10/24 (42%)
		C2H2 Zn finger	129..149	CDD:275368	7/19 (37%)
		zf-H2C2_2	142..166	CDD:290200	13/23 (57%)
		COG5048	151..>264	CDD:227381	29/112 (26%)
		C2H2 Zn finger	157..177	CDD:275368	7/19 (37%)
		C2H2 Zn finger	185..206	CDD:275368	5/20 (25%)
		C2H2 Zn finger	235..255	CDD:275368	4/19 (21%)
		C2H2 Zn finger	263..285	CDD:275368	8/21 (38%)
		C2H2 Zn finger	293..313	CDD:275368	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468928
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930