DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15436 and Zfp3

DIOPT Version :9

Sequence 1:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_808233.1	Gene:	Zfp3 / 193043	MGIID:	99177	Length:	497	Species:	Mus musculus

Alignment Length:	351	Identity:	103/351 - (29%)
Similarity:	162/351 - (46%)	Gaps:	41/351 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRVCMDISGKLVNIFDARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIRQ-- 67
            |:.|....|...::   ||..|:...|....||.             |.:.:  ::|::.|..
Mouse   166 CKECGKTFGTNSSL---RRHQRIHAGEKPFACTE-------------CGKAF--IQSSHLIHHHR 212

  Fly    68 --------TCEESHQFYCR----VRDEGIEDALCALLEEEDWEISE-DEDARIDSASAADDDGKS 119
                    .|||..:.:.:    :..:.|...      |:.:|.:| .:..|:.|......  :.
Mouse   213 IHTGERPYKCEECGKAFSQNSALILHQRIHTG------EKPYECNECGKTFRVSSQLIQHQ--RI 269

  Fly   120 DSKKVAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYEC 184
            .:::...||.||.|.::.....:||.:.|...:.:.|..|.:.|.....|..|.:.|...|||||
Mouse   270 HTEERYHECSECGKAFKHSSGLIRHQKIHTGEKPYLCNECGKGFGQSSELIRHQRIHTGDKPYEC 334

  Fly   185 SHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTR 249
            |.|.|||.|.|.:..|.|.||||:|:.|.:|.|.|..:|:|.||.|.|..|:|::|.:|.|.|.|
Mouse   335 SECGKTFGQNSEIIRHIRIHTGEKPYVCKECGKAFRGNSELLRHERIHTGEKPYECFECGKAFRR 399

  Fly   250 KFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKL 314
            ..||..|.|.||||:|.:|:.|.:.|.....|..|.::|:.::|:.||.|.|||...|.|..|:.
Mouse   400 TSHLIVHQRIHTGEKPHQCNECARTFWDNSELLLHQKIHIGEKPYECSECEKTFSQHSQLTIHQR 464

  Fly   315 VHNAERTFKCPHCASFYKQRKTLARH 340
            :|..|:.::|..|...:.:...|.||
Mouse   465 IHTGEKPYECQECQKTFSRSSHLLRH 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	15/82 (18%)
		C2H2 Zn finger	128..148	CDD:275368	6/19 (32%)
		C2H2 Zn finger	156..176	CDD:275368	5/19 (26%)
		COG5048	<180..341	CDD:227381	68/161 (42%)
		C2H2 Zn finger	184..204	CDD:275368	10/19 (53%)
		zf-H2C2_2	197..219	CDD:290200	10/21 (48%)
		C2H2 Zn finger	212..232	CDD:275368	9/19 (47%)
		zf-H2C2_2	224..249	CDD:290200	11/24 (46%)
		C2H2 Zn finger	240..260	CDD:275368	9/19 (47%)
		zf-H2C2_2	252..276	CDD:290200	11/23 (48%)
		C2H2 Zn finger	268..288	CDD:275368	5/19 (26%)
		C2H2 Zn finger	296..316	CDD:275368	9/19 (47%)
		C2H2 Zn finger	324..341	CDD:275368	5/17 (29%)
Zfp3	NP_808233.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53
		COG5048	134..494	CDD:227381	103/351 (29%)
		zf-C2H2	136..158	CDD:278523
		C2H2 Zn finger	138..158	CDD:275368
		zf-H2C2_2	150..175	CDD:290200	2/8 (25%)
		C2H2 Zn finger	166..186	CDD:275368	6/22 (27%)
		zf-H2C2_2	178..203	CDD:290200	7/42 (17%)
		C2H2 Zn finger	194..214	CDD:275368	5/34 (15%)
		zf-H2C2_2	206..231	CDD:290200	4/24 (17%)
		C2H2 Zn finger	222..242	CDD:275368	3/19 (16%)
		zf-H2C2_2	238..257	CDD:290200	4/24 (17%)
		C2H2 Zn finger	250..270	CDD:275368	3/21 (14%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		zf-H2C2_2	291..313	CDD:290200	5/21 (24%)
		C2H2 Zn finger	306..326	CDD:275368	5/19 (26%)
		zf-H2C2_2	318..341	CDD:290200	11/22 (50%)
		C2H2 Zn finger	334..354	CDD:275368	10/19 (53%)
		zf-H2C2_2	349..369	CDD:290200	10/19 (53%)
		C2H2 Zn finger	362..382	CDD:275368	9/19 (47%)
		zf-H2C2_2	374..399	CDD:290200	11/24 (46%)
		C2H2 Zn finger	390..410	CDD:275368	9/19 (47%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		zf-H2C2_2	430..455	CDD:290200	10/24 (42%)
		C2H2 Zn finger	446..466	CDD:275368	9/19 (47%)
		zf-H2C2_2	459..483	CDD:290200	6/23 (26%)
		C2H2 Zn finger	474..494	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910