DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15436 and zfp-2

DIOPT Version :9

Sequence 1:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_496055.1	Gene:	zfp-2 / 174505	WormBaseID:	WBGene00009448	Length:	422	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	74/267 - (27%)
Similarity:	120/267 - (44%)	Gaps:	28/267 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 ISEDE--DARIDSASAADDDGK--SDSKKVA--FECRECHKKYQRKGTFLRHMR-THMDGQSFPC 156
            ||.:|  :|.:|:..:..:|.|  :..|.:|  :.|..|...:..|..:.||:: .|.|.:.|.|
Worm   138 ISAEEAPEAPLDTQDSWINDPKPVTTPKALAGLYRCTNCKTYFGNKEVYQRHIQEVHGDARPFRC 202

  Fly   157 PYCKRNFRLRVTLKAHMKTHNAAKP-YECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFI 220
            ..|...|..:.::..|:|.|:..|| :.|.:|.:.|::..:...|.:.|....  .|..|.:.|.
Worm   203 FNCGMRFANKTSMTHHLKDHSLLKPMFSCDYCPRIFSKLESKTRHHKMHFTRS--TCQTCMRFFT 265

  Fly   221 KSSDLRRHIRT-----------------HGSERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKC 268
            ....||.|..|                 :|....:.||.|...|..|..:..|.|.||||:|:.|
Worm   266 TEDALRHHQSTAHPATFDSGPPPEDLLPNGKSARYSCSYCNLRFHFKKDMLVHERIHTGEKPYSC 330

  Fly   269 SHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQ 333
            .:|.|:||..|.|..|.|.|..:.|:.|..|.|.||.:|.|::|:|..:.:.....|...::..|
Worm   331 GYCMKSFAQSQALTAHIRTHTKELPYGCGKCDKRFRDNSCLRKHELAAHTDEPIVRPISVAYSNQ 395

  Fly   334 -RKTLAR 339
             :|.:.|
Worm   396 VQKQMQR 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071
		C2H2 Zn finger	128..148	CDD:275368	5/20 (25%)
		C2H2 Zn finger	156..176	CDD:275368	5/19 (26%)
		COG5048	<180..341	CDD:227381	51/179 (28%)
		C2H2 Zn finger	184..204	CDD:275368	4/19 (21%)
		zf-H2C2_2	197..219	CDD:290200	4/21 (19%)
		C2H2 Zn finger	212..232	CDD:275368	7/36 (19%)
		zf-H2C2_2	224..249	CDD:290200	9/41 (22%)
		C2H2 Zn finger	240..260	CDD:275368	7/19 (37%)
		zf-H2C2_2	252..276	CDD:290200	10/23 (43%)
		C2H2 Zn finger	268..288	CDD:275368	9/19 (47%)
		C2H2 Zn finger	296..316	CDD:275368	9/19 (47%)
		C2H2 Zn finger	324..341	CDD:275368	4/17 (24%)
zfp-2	NP_496055.1	C2H2 Zn finger	173..194	CDD:275368	5/20 (25%)
		C2H2 Zn finger	202..222	CDD:275368	5/19 (26%)
		C2H2 Zn finger	231..251	CDD:275368	4/19 (21%)
		COG5048	<251..>358	CDD:227381	32/108 (30%)
		C2H2 Zn finger	257..278	CDD:275368	7/20 (35%)
		C2H2 Zn finger	302..322	CDD:275368	7/19 (37%)
		C2H2 Zn finger	330..350	CDD:275368	9/19 (47%)
		C2H2 Zn finger	358..374	CDD:275368	7/15 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I3381
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050