DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15436 and si:dkey-122c11.8

DIOPT Version :9

Sequence 1:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_017211097.1	Gene:	si:dkey-122c11.8 / 108183696	ZFINID:	ZDB-GENE-110913-23	Length:	358	Species:	Danio rerio

Alignment Length:	285	Identity:	89/285 - (31%)
Similarity:	147/285 - (51%)	Gaps:	14/285 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 EDVKSAYGIRQTCEESHQFYCRVRDEGIEDALCALLEEEDWEISEDEDARIDSASAADDDGKSDS 121
            ||::....:....|::||     ::|         :||:..:::.||...:...:.:....:...
Zfish    22 EDLQEQTDLMLLKEKTHQ-----QNE---------MEEKQQDMTTDEKPTLTKKTLSRGRPRKSK 72

  Fly   122 KKVAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSH 186
            .:..|.|::|.|.:.:|.....|:|.|...:::.|..|.::|.....|..||:.|...:||.|..
Zfish    73 PRCNFSCKQCGKSFSQKPKLDVHIRDHTREKAYTCKQCGKSFYNTRNLTVHMRIHTGERPYTCQQ 137

  Fly   187 CAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKF 251
            |.|:|.:...|..|.|.||||||:.|.||.|:|..:.:|..|:|.|..|:|:.|.:|.|::::..
Zfish   138 CGKSFHKTGNLTVHLRIHTGERPYTCQQCGKSFQTTGNLTVHMRIHTGEKPYSCPQCGKSYSQNS 202

  Fly   252 HLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVH 316
            :|:.|.|:|.|.|.|.|:.|.|.|..||:|..|.|:|..::|:.|:.|.|:|...||||.|.:||
Zfish   203 NLEVHMRTHNGGRTFVCTQCGKRFVKKQNLDLHMRIHTGEKPYTCTECGKSFPYKSTLKHHMIVH 267

  Fly   317 NAERTFKCPHCASFYKQRKTLARHI 341
            ..|:.|.|..|...:.....|..|:
Zfish   268 TGEKPFACAQCGKSFTCNANLRNHM 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	5/20 (25%)
		C2H2 Zn finger	128..148	CDD:275368	6/19 (32%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	<180..341	CDD:227381	63/160 (39%)
		C2H2 Zn finger	184..204	CDD:275368	7/19 (37%)
		zf-H2C2_2	197..219	CDD:290200	13/21 (62%)
		C2H2 Zn finger	212..232	CDD:275368	8/19 (42%)
		zf-H2C2_2	224..249	CDD:290200	9/24 (38%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-H2C2_2	252..276	CDD:290200	10/23 (43%)
		C2H2 Zn finger	268..288	CDD:275368	9/19 (47%)
		C2H2 Zn finger	296..316	CDD:275368	9/19 (47%)
		C2H2 Zn finger	324..341	CDD:275368	3/16 (19%)
si:dkey-122c11.8	XP_017211097.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910