DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL27A and RPL27A

DIOPT Version :9

Sequence 1:	NP_001188689.2	Gene:	RpL27A / 33654	FlyBaseID:	FBgn0285948	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_000981.1	Gene:	RPL27A / 6157	HGNCID:	10329	Length:	148	Species:	Homo sapiens

Alignment Length:	143	Identity:	99/143 - (69%)
Similarity:	120/143 - (83%)	Gaps:	0/143 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGMHHHRINFDKYHPGYFGKVGMRNFHLRRQHKFR 71
            :|||||||||||||||||||||||||||||||:||||||||||||||||||||:::||:|...|.
Human     6 RKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGLHHHRINFDKYHPGYFGKVGMKHYHLKRNQSFC 70

  Fly    72 PEINLDKLWSLVGAEKFAELEKEKSTKAPVIDLVKFGYYKLLGRGHLPARPVIVKAKYFSKKAED 136
            |.:||||||:||..:......|.|:..||:||:|:.||||:||:|.||.:|||||||:||::||:
Human    71 PTVNLDKLWTLVSEQTRVNAAKNKTGAAPIIDVVRSGYYKVLGKGKLPKQPVIVKAKFFSRRAEE 135

  Fly   137 KIKKAGGVCLLSA 149
            |||..||.|:|.|
Human   136 KIKSVGGACVLVA 148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL27A	NP_001188689.2	PTZ00160	7..149	CDD:185489	98/141 (70%)
RPL27A	NP_000981.1	PTZ00160	1..148	CDD:185489	98/141 (70%)
RPL27A	NP_000981.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..38		30/31 (97%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146914
Domainoid	1	1.000	178	1.000	Domainoid score	I3587
eggNOG	1	0.900	-	-		E1_COG0200
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H115477
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3502
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53607
OrthoDB	1	1.010	-	-		D1445443at2759
OrthoFinder	1	1.000	-	-		FOG0001387
OrthoInspector	1	1.000	-	-		oto91142
orthoMCL	1	0.900	-	-		OOG6_100748
Panther	1	1.100	-	-	LDO	PTHR11721
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1123
SonicParanoid	1	1.000	-	-		X1116
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800