DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gs1l and DOG1

DIOPT Version :9

Sequence 1:NP_477228.1 Gene:Gs1l / 33653 FlyBaseID:FBgn0019982 Length:231 Species:Drosophila melanogaster
Sequence 2:NP_011910.1 Gene:DOG1 / 856440 SGDID:S000001086 Length:246 Species:Saccharomyces cerevisiae


Alignment Length:219 Identity:55/219 - (25%)
Similarity:82/219 - (37%) Gaps:72/219 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 CVFDMDGLLLDTERLYTVATE----MILEPYGKTYPFEIKEQVMGLQT-EPLARFMVEHYELPMS 71
            |:||:||.::.|    |||.|    .:...|| ..|.|:.:...|.:| |.|.||..:       
Yeast     9 CLFDLDGTIVST----TVAAEKAWTKLCYEYG-VDPSELFKHSHGARTQEVLRRFFPK------- 61

  Fly    72 WEEYARQQRANTEIL----------MRNAQLMPGAERLLRHLHAN-----KVP---FCLATSSGA 118
                 .....|..:|          :....|:||||.||..|..:     |:|   :.:.||...
Yeast    62 -----LDDTDNKGVLALEKDIAHSYLDTVSLIPGAENLLLSLDVDTETQKKLPERKWAIVTSGSP 121

  Fly   119 DMVELKTAQHRELFSLFNH--KVCGS-----SDKEVVNGKPAPDIF----------LVAAGRFGV 166
            .:.          ||.|..  |..|.     :..:|.||||.|:.:          |...|:   
Yeast   122 YLA----------FSWFETILKNVGKPKVFITGFDVKNGKPDPEGYSRARDLLRQDLQLTGK--- 173

  Fly   167 PPKPSDCLVFEDSPNGVTAANSAG 190
              :....:||||:|.|:.|..:.|
Yeast   174 --QDLKYVVFEDAPVGIKAGKAMG 195

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gs1lNP_477228.1 YcjU 12..220 CDD:223710 55/219 (25%)
HAD_like 16..231 CDD:304363 52/215 (24%)
DOG1NP_011910.1 HAD_ScGPP-like 9..231 CDD:319829 55/219 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0637
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X845
TreeFam 00.000 Not matched by this tool.
32.810

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