DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gs1l and R151.10

DIOPT Version :9

Sequence 1:	NP_477228.1	Gene:	Gs1l / 33653	FlyBaseID:	FBgn0019982	Length:	231	Species:	Drosophila melanogaster
Sequence 2:	NP_001379936.1	Gene:	R151.10 / 24104817	WormBaseID:	WBGene00020113	Length:	233	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	92/229 - (40%)
Similarity:	127/229 - (55%)	Gaps:	8/229 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VTHCVFDMDGLLLDTERLYTVATEMILEPYGKTYPFEIKEQVMGLQTEPLARFMVEHYELP--MS 71
            |||.:||.||||:|||..||.|...:|..||..:..::|.:.||.:.:...|:::...::.  ::
Worm     5 VTHVIFDFDGLLVDTESAYTEANMELLRKYGHVFTMDLKRRQMGKRHDESIRWLINELKIGDLVT 69

  Fly    72 WEEYARQQRANTEILMRNAQLMPGAERLLRHLHANKVPFCLATSSGADMVELKTAQHRELFSLFN 136
            .|||:||.......:.:.:..|||||:|:|||....||..|.|.|.:.....|...|::..::..
Worm    70 PEEYSRQYDELLIEMFKRSPAMPGAEKLVRHLLHTGVPVALCTGSCSRTFPTKLDNHKDWVNMIK 134

  Fly   137 HKVCGSSDKEVVNGKPAPDIFLVAAGRFGVPPKPSD-CLVFEDSPNGVTAANSAGMQVVMVP--- 197
            .:|....|.||.:|||.||.|||...||...|:.:| .||||||.|||.:|..||||.||||
Worm   135 LQVLSGDDPEVKHGKPHPDPFLVTMKRFPQVPESADKVLVFEDSYNGVLSALDAGMQCVMVPERS 199

  Fly   198 --DPRLSQEKTSHATQVLASLADFKPEQFGLPAF 229
              ||....|..:..|.:|.||..||||.||||.:
Worm   200 IFDPDSDPEFKNRVTVILNSLEQFKPEDFGLPPY 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gs1l	NP_477228.1	YcjU	12..220	CDD:223710	81/215 (38%)
Gs1l	NP_477228.1	HAD_like	16..231	CDD:304363	87/222 (39%)
R151.10	NP_001379936.1	HAD_AtGPP-like	5..197	CDD:319831	76/191 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167026
Domainoid	1	1.000	128	1.000	Domainoid score	I3303
eggNOG	1	0.900	-	-		E1_COG0637
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	155	1.000	Inparanoid score	I2920
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57193
OrthoDB	1	1.010	-	-		D1510544at2759
OrthoFinder	1	1.000	-	-		FOG0001355
OrthoInspector	1	1.000	-	-		otm14485
orthoMCL	1	0.900	-	-		OOG6_100310
Panther	1	1.100	-	-	LDO	PTHR18901
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1909
SonicParanoid	1	1.000	-	-		X845
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.840