DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Secp43 and NAM8

DIOPT Version :9

Sequence 1:	NP_608837.2	Gene:	Secp43 / 33652	FlyBaseID:	FBgn0031607	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_011954.1	Gene:	NAM8 / 856486	SGDID:	S000001128	Length:	523	Species:	Saccharomyces cerevisiae

Alignment Length:	217	Identity:	72/217 - (33%)
Similarity:	109/217 - (50%)	Gaps:	37/217 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QLWMGSLESYMTENFIIAAFRKMGEDPTTVRLMRNKYTGEPA----------GYCFVNFISDDHA 61
            ||:||.|:....:|.:...:..:||....||:|.|......:          |||||:|.|..||
Yeast    55 QLYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTHA 119

  Fly    62 LDAMHKLNGKPIPGTNPIVRFRLNSASNSYKLPGNE-------REFSVWVGDLSSDVDDYQLYKV 119
            .:|:.| ||..||.. |..:.:||.|::||....|.       ...|::||||:.:|.:.||:::
Yeast   120 ANALLK-NGMLIPNF-PNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVTESQLFEL 182

  Fly   120 FSSKFTSIKTAKVILDSL-GFSKGYGFVRFGIEDEQKSALYDMNGYIGLGTKPIKICNAVPKPKS 183
            |.:::.|...||::.|.: |.|||||||:|...|||:.||.:|.| :.|..:.||:
Yeast   183 FINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQG-VFLNGRAIKV--------- 237

  Fly   184 ELGGAVGE-----GNTNYGYGS 200
              |...|:     ||.:|...|
Yeast   238 --GPTSGQQQHVSGNNDYNRSS 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Secp43	NP_608837.2	RRM1_SECp43	7..90	CDD:241054	31/92 (34%)
Secp43	NP_608837.2	RRM2_SECp43	99..180	CDD:241056	32/81 (40%)
NAM8	NP_011954.1	RRM1_NGR1_NAM8_like	55..144	CDD:410023	30/90 (33%)
		RRM2_SECp43_like	162..241	CDD:409781	33/90 (37%)
		RRM3_NGR1_NAM8_like	312..383	CDD:409782
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I2591
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001306
OrthoInspector	1	1.000	-	-		otm46874
orthoMCL	1	0.900	-	-		OOG6_102296
Panther	1	1.100	-	-	LDO	PTHR47640
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1842
SonicParanoid	1	1.000	-	-		X1010
TreeFam	0	0.000	Not matched by this tool.
	8	7.940