DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Secp43 and trnau1apb

DIOPT Version :9

Sequence 1:	NP_608837.2	Gene:	Secp43 / 33652	FlyBaseID:	FBgn0031607	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001025137.2	Gene:	trnau1apb / 791478	ZFINID:	ZDB-GENE-040426-2386	Length:	316	Species:	Danio rerio

Alignment Length:	335	Identity:	124/335 - (37%)
Similarity:	173/335 - (51%)	Gaps:	45/335 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LWMGSLESYMTENFIIAAFRKMGEDPTTVRLMRNKYTGEPAGYCFVNFISDDHALD-AMHKLNGK 71
            ||||.|:.||.||||..||..|||....|:::.::.||..||||||. ::|:.::| .:.:||||
Zfish     8 LWMGDLDPYMDENFIKQAFSTMGETAFGVKIITHRVTGGSAGYCFVE-MADEASVDRCVQRLNGK 71

  Fly    72 PIPGTNPIVRFRLNSASNSYKLPGNEREFSVWVGDLSSDVDDYQLYKVFSSKFTSIKTAKVILDS 136
            .:||:||..:|:||.|:.. |.|....||||:||||:|:||||||::.|..||.|.|.|||:.|.
Zfish    72 LVPGSNPPRKFKLNYATYG-KRPEPGPEFSVFVGDLTSEVDDYQLHQFFLKKFPSCKGAKVVTDP 135

  Fly   137 LGFSKGYGFVRFGIEDEQKSALYDMNGYIGLGTKPIKICNAVPKPKSELGGAVGEGNTNYGYGSG 201
            .|.|:|||||:|..|:|||.||.:.....|||.|||:|..||.|
Zfish   136 YGNSRGYGFVKFSDENEQKKALEEFQNASGLGGKPIRISIAVNK--------------------- 179

  Fly   202 MTAAGGTDYSQYYDPTSTYWQGYQAWQGYYEQAGASITDAAAYYQQAMSQSHS------NPQTLA 260
                 |...|.|::..:||...||  |.||:|...|      ||.|.....:|      ||....
Zfish   180 -----GNKASTYHNQNNTYNTNYQ--QQYYQQPYNS------YYPQWGYDQYSGYNYGYNPYAAP 231

  Fly   261 QHAEAWSAQRSAQYEQQQQQQTASAANGAE--DENGLVEHKFVLDVDKLNREAIDADRRLYDALE 323
            ...................|.:..|.:|.|  :|:...:....:||::|||:.::....|||:|.
Zfish   232 PPMMGPPPPMGMPPMPPDMQGSTEAHDGTEEVEEDPSEDPNPQVDVEELNRQYMERSEELYDSLM 296

  Fly   324 SSKWLPIEQL 333
            ...|||::.:
Zfish   297 ECHWLPMDTI 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Secp43	NP_608837.2	RRM1_SECp43	7..90	CDD:241054	39/82 (48%)
Secp43	NP_608837.2	RRM2_SECp43	99..180	CDD:241056	47/80 (59%)
trnau1apb	NP_001025137.2	RRM1_SECp43	7..90	CDD:241054	39/82 (48%)
		RRM2_SECp43	98..179	CDD:241056	47/80 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	239..285		10/45 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8820
eggNOG	1	0.900	-	-		E33208_3BEHN
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49509
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3929
OMA	1	1.010	-	-		QHG47468
OrthoDB	1	1.010	-	-		D514475at33208
OrthoFinder	1	1.000	-	-		FOG0001306
OrthoInspector	1	1.000	-	-		otm25614
orthoMCL	1	0.900	-	-		OOG6_102296
Panther	1	1.100	-	-	LDO	PTHR47640
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1842
SonicParanoid	1	1.000	-	-		X1010
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.870