DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Secp43 and tial1

DIOPT Version :9

Sequence 1:	NP_608837.2	Gene:	Secp43 / 33652	FlyBaseID:	FBgn0031607	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	XP_005156854.1	Gene:	tial1 / 394107	ZFINID:	ZDB-GENE-040426-1547	Length:	399	Species:	Danio rerio

Alignment Length:	371	Identity:	84/371 - (22%)
Similarity:	122/371 - (32%)	Gaps:	120/371 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LWMGSLESYMTENFIIAAFRKMG---------EDPTTVRLMRNKYTG---------EPAGYCFVN 54
            |::|:|...:|||.|:..|.::|         |...:.|.|.:...|         :|  ||||.
Zfish    10 LYVGNLSRDVTENLILQLFTQIGPCKSCKMITEQSDSSRKMNSSSIGFSVLQHTSNDP--YCFVE 72

  Fly    55 FISDDHALDAMHKLNGKPIPGTNPIVRFRLNSASNSYKLPGNEREFSVWVGDLSSDVDDYQLYKV 119
            |.....|..|:..:||:.|.|....|.:....:|..   ......|.|:|||||.::....:...
Zfish    73 FFEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQK---KDTSNHFHVFVGDLSPEITTDDIRAA 134

  Fly   120 FSSKFTSIKTAKVILD-SLGFSKGYGFVRF-----------GIEDEQKSALYDMNGYIGLGTKPI 172
            | :.|..|..|:|:.| :.|.|||||||.|           .::|.: :|:..|.|. .||.:.|
Zfish   135 F-APFGKISDARVVKDMTTGKSKGYGFVSFYNKLVRLQYRNRVKDAE-NAIVHMGGQ-WLGGRQI 196

  Fly   173 KICNAV---PKPKSELG------------------------GAVGEGNTNY-------------- 196
            :...|.   |.|||...                        |.:..|.|.:
Zfish   197 RTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIME 261

  Fly   197 -------GY-----------GSGMTAAGGTDYSQYYDPTSTYWQGYQAWQGYYEQAGASITDAAA 243
                   ||           ...:.:..||....:.  ...||             |....|.|.
Zfish   262 IRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHV--VKCYW-------------GKESPDMAK 311

  Fly   244 YYQQ-------AMSQSHSNPQTLAQH-AEAWSAQRSAQYEQQQQQQ 281
            ..|.       ..:|.:.|||...|: ...|.......|.|...||
Zfish   312 NVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQ 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Secp43	NP_608837.2	RRM1_SECp43	7..90	CDD:241054	27/99 (27%)
Secp43	NP_608837.2	RRM2_SECp43	99..180	CDD:241056	30/95 (32%)
tial1	XP_005156854.1	RRM	7..295	CDD:223796	68/292 (23%)
		RRM_SF	9..108	CDD:302621	27/99 (27%)
		RRM2_TIAR	114..203	CDD:241061	30/91 (33%)
		RRM3_TIAR	233..305	CDD:241064	10/86 (12%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1842
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940