DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Secp43 and CG3335

DIOPT Version :9

Sequence 1:	NP_608837.2	Gene:	Secp43 / 33652	FlyBaseID:	FBgn0031607	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_648337.1	Gene:	CG3335 / 39119	FlyBaseID:	FBgn0036018	Length:	918	Species:	Drosophila melanogaster

Alignment Length:	340	Identity:	70/340 - (20%)
Similarity:	122/340 - (35%)	Gaps:	84/340 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QLWMGSLESYMTENFIIAAFRKMGEDPTT-VRLMRNKYTGEPAGYCFVNFISDDHALDAMHKLNG 70
            :::..:|....||..:...|.:.|  |.. |.|..:|.|.:..|:..|.::..:|||.|.:.|:|
  Fly   365 RIFFRNLAYTTTEEDLRKLFEQFG--PVVEVNLPLDKLTRKIKGFGTVTYMMPEHALKAFNTLDG 427

  Fly    71 KPIPG------------TNPIVRFRLNSASNSY------KLPGNEREFSVW----VGDLSSDVDD 113
            ....|            .||......|.||.|:      ||..|.::...|    :|..:
  Fly   428 TDFHGRLLHLLPSKDIEKNPKEDLDENDASLSFKEKKALKLKKNAQKPIGWNTLFLGANA----- 487

  Fly   114 YQLYKVFSSKFTSIKTAKV-ILDSLGFSKG--YGFVRFGIED-----EQKSALYDMNGYIGLGTK 170
              :.::.:.:|   ||:|. |||:   |.|  ...||..:.:     |.|..|.:....:....:
  Fly   488 --VAEILAKQF---KTSKERILDT---SDGGSSAAVRLALGETQVVIEMKRFLEEEGVRLDAFDE 544

  Fly   171 PIK-------ICNAVPKPK--SELG------GAVGEGNTNYGYGSGMTAAGGTDYSQYYDPTSTY 220
            |.|       :...:|...  ||:.      |.:|.        ..:..:|.|...:|.||
  Fly   545 PAKKRSNTVILAKNLPAATEISEITPIFSRFGPIGR--------IVLPPSGVTALIEYCDP---- 597

  Fly   221 WQGYQAWQGYYEQAGASITDAAAYYQQAMSQSHSN--------PQTLAQHAEAWSAQRSAQYEQQ 277
               .:|.|.:.:.|.:...:|..|.:.|..|..:.        |::..:..|....:........
  Fly   598 ---LEARQAFKKLAYSKFKNAPLYLEWAPEQVFTKTLSGEPVIPKSEPKPKEEVKPEEKPIVNDA 659

  Fly   278 QQQQTASAANGAEDE 292
            :..:..|.|..|:||
  Fly   660 KPDEEDSRAEDADDE 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Secp43	NP_608837.2	RRM1_SECp43	7..90	CDD:241054	24/95 (25%)
Secp43	NP_608837.2	RRM2_SECp43	99..180	CDD:241056	18/99 (18%)
CG3335	NP_648337.1	RRM1_RBM19	2..77	CDD:241008
		RRM_SF	250..314	CDD:302621
		RRM3_RBM19	362..440	CDD:241011	19/76 (25%)
		RRM4_RBM19	552..623	CDD:241013	15/85 (18%)
		RRM	<638..845	CDD:223796	7/37 (19%)
		RRM5_RBM19_like	679..760	CDD:240764
		RRM6_RBM19	785..864	CDD:241015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463929
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930