DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Secp43 and csx1

DIOPT Version :9

Sequence 1:	NP_608837.2	Gene:	Secp43 / 33652	FlyBaseID:	FBgn0031607	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_594243.1	Gene:	csx1 / 2542151	PomBaseID:	SPAC17A2.09c	Length:	632	Species:	Schizosaccharomyces pombe

Alignment Length:	202	Identity:	74/202 - (36%)
Similarity:	107/202 - (52%)	Gaps:	20/202 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LWMGSLESYMTENFIIAAFRKMGEDPTTVRLMRNKYTGEPA--GYCFVNFISDDHALDAMHKLNG 70
            ||||.||.:|...||...:..:.| |..|::||:|.:....  .||||.|.|...|..|:.|.|.
pombe    87 LWMGDLEPWMDATFIQQLWASLNE-PVNVKVMRSKASSSETLISYCFVQFSSSAAAERALMKYNN 150

  Fly    71 KPIPGTNPIVRFRLNSAS------NSYKLPGNEREFSVWVGDLSSDVDDYQLYKVFSSKFTSIKT 129
            ..|||.:  ..|:||.|:      |::  ...:.|||::||||....:|..|:..|.|.:.|..:
pombe   151 TMIPGAH--CTFKLNWATGGGIQHNNF--VSRDPEFSIFVGDLLPTTEDSDLFMTFRSIYPSCTS 211

  Fly   130 AKVILDSL-GFSKGYGFVRFGIEDEQKSALYDMNGYIGLGTKPIKICNAVPKPKSELG-----GA 188
            ||:|:|.: |.|:.||||||..|.||:.||..|.||:..| :|::|..|.||.::.:.     |.
pombe   212 AKIIVDPVTGLSRKYGFVRFSSEKEQQHALMHMQGYLCQG-RPLRISVASPKSRASIAADSALGI 275

  Fly   189 VGEGNTN 195
            |....:|
pombe   276 VPTSTSN 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Secp43	NP_608837.2	RRM1_SECp43	7..90	CDD:241054	32/89 (36%)
Secp43	NP_608837.2	RRM2_SECp43	99..180	CDD:241056	36/81 (44%)
csx1	NP_594243.1	RRM	67..367	CDD:223796	74/202 (37%)
		RRM1_NGR1_NAM8_like	86..168	CDD:241055	32/83 (39%)
		RRM2_NGR1_NAM8_like	181..260	CDD:241057	35/79 (44%)
		half-pint	<217..>577	CDD:130706	26/67 (39%)
		RRM3_NGR1_NAM8_like	296..367	CDD:240792
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I2755
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001306
OrthoInspector	1	1.000	-	-		otm47328
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1842
SonicParanoid	1	1.000	-	-		X1010
TreeFam	1	0.960	-	-
	7	6.900