DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Secp43 and SPBC23E6.01c

DIOPT Version :9

Sequence 1:	NP_608837.2	Gene:	Secp43 / 33652	FlyBaseID:	FBgn0031607	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_596601.2	Gene:	SPBC23E6.01c / 2540551	PomBaseID:	SPBC23E6.01c	Length:	473	Species:	Schizosaccharomyces pombe

Alignment Length:	182	Identity:	83/182 - (45%)
Similarity:	118/182 - (64%)	Gaps:	9/182 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LWMGSLESYMTENFIIAAFRKMGEDPTTVRLMRNKYTGEPAGYCFVNFISDDHALDAMHKLNGKP 72
            ||||.||.::||.||...:..:|: ...|:|:||:|||..||||||.|.|...|..|| .:|.||
pombe    95 LWMGELEPWVTEAFIQQVWNTLGK-AVKVKLIRNRYTGMNAGYCFVEFASPHEASSAM-SMNNKP 157

  Fly    73 IPGTNPIVRFRLNSASNS---YKLPGNEREFSVWVGDLSSDVDDYQLYKVFSSKFTSIKTAKVIL 134
            |||||.:  |:||.||..   .|......|:|::|||||.:|:::.:|.:|:|::.|.|:||::.
pombe   158 IPGTNHL--FKLNWASGGGLREKSISKASEYSIFVGDLSPNVNEFDVYSLFASRYNSCKSAKIMT 220

  Fly   135 D-SLGFSKGYGFVRFGIEDEQKSALYDMNGYIGLGTKPIKICNAVPKPKSEL 185
            | ....|:|||||||..|::|||||.:|.|.| .|.:||::..|.||.|:.:
pombe   221 DPQTNVSRGYGFVRFTDENDQKSALAEMQGQI-CGDRPIRVGLATPKSKAHV 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Secp43	NP_608837.2	RRM1_SECp43	7..90	CDD:241054	42/81 (52%)
Secp43	NP_608837.2	RRM2_SECp43	99..180	CDD:241056	37/81 (46%)
SPBC23E6.01c	NP_596601.2	RRM	70..376	CDD:223796	83/182 (46%)
		RRM1_NGR1_NAM8_like	94..173	CDD:241055	42/81 (52%)
		RRM2_NGR1_NAM8_like	185..264	CDD:241057	36/79 (46%)
		RRM3_NGR1_NAM8_like	302..373	CDD:240792
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2705
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001306
OrthoInspector	1	1.000	-	-		otm47328
orthoMCL	1	0.900	-	-		OOG6_102296
Panther	1	1.100	-	-	LDO	PTHR47640
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1842
SonicParanoid	1	1.000	-	-		X1010
TreeFam	1	0.960	-	-
	9	8.900