Protein Alignment Secp43 and Ncl

DIOPT Version :10

• Sequence 1: NP_608837.2
• Gene: Secp43 / 33652
• FlyBaseID: FBgn0031607
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_036881.2
• Gene: Ncl / 25135
• RGDID: 3153
• Length: 714
• Species: Rattus norvegicus
• Alignment Length: 208
• Identity: 59/208 - (28%)
• Similarity: 97/208 - (46%)
• Gaps: 25/208 - (12%)

  Fly     9 WMGSLESYMTENFIIAA----FRKMGEDPTTVRLMRNKYTGEPAGYCFVNFISDDHALDAMHKLN 69
            |.|..::.:..|...:|    .:::.|..|.:::.:|.: |:..||.|:.|.|.:.|.:|::..|
  Rat   485 WSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNPH-GKSKGYAFIEFASFEDAKEALNSCN 548

  Fly    70 GKPIPGTNPIVRFRL---NSASNSYKLPGNEREFSVWVGDLSSDVDDYQLYKVFSSKFTSIKTAK 131
            ...|.|..  :|..|   ..:.|:...|..    :::|..||.|..:..|.:.|..   |:: |:
  Rat   549 KMEIEGRT--IRLELQGPRGSPNARSQPSK----TLFVKGLSEDTTEETLKESFEG---SVR-AR 603

  Fly   132 VILD-SLGFSKGYGFVRFGIEDEQKSALYDM-NGYIGLGTKPIKICNAVPKPKSELGGAVGEGNT 194
            ::.| ..|.|||:|||.|..|::.|:|...| :|.|. |.   |:.....|||.| ||..|.|..
  Rat   604 IVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEID-GN---KVTLDWAKPKGE-GGFGGRGGG 663

  Fly   195 NYGYGSGMTAAGG 207
            ..|:|......||
  Rat   664 RGGFGGRGGGRGG 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Secp43	NP_608837.2	RRM1_SECp43	7..90	CDD:410022	20/87 (23%)
		RRM2_SECp43_like	99..178	CDD:409781	25/80 (31%)
		Trnau1ap	210..330	CDD:465438
Ncl	NP_036881.2	8 X 8 AA tandem repeats of X-T-P-X-K-K-X-X	58..135
		RRM1_NCL	312..386	CDD:409837
		RRM2_NCL	395..470	CDD:409838
		RRM3_NCL	489..561	CDD:409839	17/74 (23%)
		RRM4_NCL	576..653	CDD:409840	27/88 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	646..714		12/32 (38%)