DRSC/TRiP Functional Genomics Resources

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Protein Alignment Secp43 and RBM34

DIOPT Version :10

Sequence 1:NP_608837.2 Gene:Secp43 / 33652 FlyBaseID:FBgn0031607 Length:336 Species:Drosophila melanogaster
Sequence 2:NP_055829.2 Gene:RBM34 / 23029 HGNCID:28965 Length:430 Species:Homo sapiens


Alignment Length:183 Identity:47/183 - (25%)
Similarity:77/183 - (42%) Gaps:35/183 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 GSLESYMTENFI---------IAAF-RKMGEDPTTVRLMRNKYTGEPAGYCFVNFISDDHALDAM 65
            |.:||....:.|         :||. ||:..|...:.             .:|.|..:..|..|:
Human   209 GQIESVRFRSLIPAEGTLSKKLAAIKRKIHPDQKNIN-------------AYVVFKEESAATQAL 260

  Fly    66 HKLNGKPIPGTNPIVRFRLNSASNSYKLPGNEREFSVWVGDLSSDVDDYQLYKVFSSKFTSIKTA 130
             |.||..|...   .|.|::.||.:    .:..:.||:||:|...|::..:.|.|.. ..||...
Human   261 -KRNGAQIADG---FRIRVDLASET----SSRDKRSVFVGNLPYKVEESAIEKHFLD-CGSIMAV 316

  Fly   131 KVILDSL-GFSKGYGFVRFGIEDEQKSALYDMNGYIGLGTKPIKICNAVPKPK 182
            :::.|.: |..||:|:|.|...|....|| .:|....:|.| :::..:|.|.|
Human   317 RIVRDKMTGIGKGFGYVLFENTDSVHLAL-KLNNSELMGRK-LRVMRSVNKEK 367

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Secp43NP_608837.2 RRM1_SECp43 7..90 CDD:410022 21/88 (24%)
RRM2_SECp43_like 99..178 CDD:409781 23/79 (29%)
Trnau1ap 210..330 CDD:465438
RBM34NP_055829.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..55
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..123
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 134..153
RRM1_RBM34 185..276 CDD:409828 19/83 (23%)
RRM2_RBM34 288..360 CDD:409829 23/74 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 365..395 2/3 (67%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 411..430
Blue background indicates that the domain is not in the aligned region.

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