DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Secp43 and HNRNPA0

DIOPT Version :9

Sequence 1:	NP_608837.2	Gene:	Secp43 / 33652	FlyBaseID:	FBgn0031607	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_006796.1	Gene:	HNRNPA0 / 10949	HGNCID:	5030	Length:	305	Species:	Homo sapiens

Alignment Length:	241	Identity:	61/241 - (25%)
Similarity:	104/241 - (43%)	Gaps:	28/241 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CQLWMGSLESYMTENFIIAAFRKMGEDPTTVRLMRNKYTGEPAGYCFVNFISDDHALDAM----H 66
            |:|::|.|....:|:.:...|...| ..|...::.|..|.....:.||.:.:.:.|..||    |
Human     7 CKLFIGGLNVQTSESGLRGHFEAFG-TLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPH 70

  Fly    67 KLNGKPIPGTNPIVRFRLNSASNSYKLPGNEREFSVWVGDLSSDVDDYQLYKVFSSKFTSIKTAK 131
            .::|      |.:...|..|..:|.:...:.:...::||.|..||.:..|.:.| |:|.:::.|:
Human    71 AVDG------NTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHF-SQFGTVEKAE 128

  Fly   132 VILD-SLGFSKGYGFVRFGIED-EQKSALYDMNGYIGLGTKPIKICNAVPK-----------PKS 183
            :|.| ..|..:|:|||.|...| ..|:|:...:...|   ..:::..||||           .:|
Human   129 IIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQG---HRVEVKKAVPKEDIYSGGGGGGSRS 190

  Fly   184 ELGGAVGEGNTNYGYGSGMTAAGGTDYSQYYDPTSTYWQGYQAWQG 229
            ..||..|.|.......:|::..||..|:.|.........||.|:.|
Human   191 SRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGG 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Secp43	NP_608837.2	RRM1_SECp43	7..90	CDD:241054	19/86 (22%)
Secp43	NP_608837.2	RRM2_SECp43	99..180	CDD:241056	24/82 (29%)
HNRNPA0	NP_006796.1	RRM1_hnRNPA0	5..83	CDD:240772	19/82 (23%)
		RRM2_hnRNPA0	99..178	CDD:241023	26/82 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..214		9/39 (23%)
		HnRNPA1	255..>269	CDD:314495
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..305
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910