Protein Alignment CG15439 and Phf14

DIOPT Version :10

• Sequence 1: NP_608836.1
• Gene: CG15439 / 33651
• FlyBaseID: FBgn0031606
• Length: 1008
• Species: Drosophila melanogaster
• Sequence 2: XP_006505259.1
• Gene: Phf14 / 75725
• MGIID: 1923539
• Length: 946
• Species: Mus musculus
• Alignment Length: 1053
• Identity: 318/1053 - (30%)
• Similarity: 436/1053 - (41%)
• Gaps: 372/1053 - (35%)

  Fly    14 LLDF---------DLGESSSDSDFLPDI---DNCSDGSKDESDGDGSSSDASGGSDSESDSDAES 66
            ||||         |..:|..|:|:.|.:   ...|...|:.||||....| ..||.||.|.:.|.
Mouse   184 LLDFVSMEELNAMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDD-DEGSGSEEDENDEG 247

  Fly    67 EDSTLQLRQLLAETEPSPLENGINGVDHCAASSPAAPVVPRA----------------PLQLSSA 115
            .|.                       ||.:.:|.|.....|:                .|.||.:
Mouse   248 NDE-----------------------DHSSPASEAGGKKKRSKVLSRNSADDEELTNDSLTLSQS 289

  Fly   116 PAKR--------------------MCCVCLGERSDDVNEIVECDSCGVSVHEGCYGV-SDNVSIS 159
            .:..                    :||||||:.|:|.:||::||:||::|||||||| .::.||.
Mouse   290 KSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIM 354

  Fly   160 STNSTCSTEPWFCEACRAGVSEPDCELCPNKGGIYKETDVGKWVHLICALYVPGVAFGEVEQLSS 224
            |:.|..|||||||:||:.||| |.||||||:.||:||||.|:|||::|||||||||||::::|..
Mouse   355 SSASENSTEPWFCDACKCGVS-PSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRP 418

  Fly   225 VTLFEMQYSKWGAKVCSLCENALFARTGVCIGCDAGMCKTYFHVTCAQVAGFLIEAHHEDDAADP 289
            |||.||.|||:|||.||.||:..||||||||.||||||:.||||||||..|.|.||..|:|.|||
Mouse   419 VTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADP 483

  Fly   290 FYAHCKVHSEKEMIKKRRRNYHTLR--LNMMQRAREKEALAAEHETPAPHPNPAQARIQRKLLKI 352
            |:|:||.|:::...|.:|:||..|:  ..|..:.|||: |:.|          |||||..:|.:.
Mouse   484 FFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQ-LSPE----------AQARINARLQQY 537

  Fly   353 QHKYTRHKELKPTPWVPTQKMSRLLTTSASACRRLLAKAEIMSVDVQHLEQREAHINALTDIRKK 417
            :.|....:..:|..|||.:|:.|.||:||||.|:|:.|||:|.:.........:..::..|.|:|
Mouse   538 RAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRK 602

  Fly   418 WHIAPAFSVEFTAYYMDRIVRMDDFRQQQRELISHNAILSKDQDVLRAQYDTALEERKAVKATKD 482
             |..||.:.:|..||.:|.:||...::...|..:....|..:|:.|..:|:...|..:.::....
Mouse   603 -HKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNG 666

  Fly   483 SLLTSIKSLHTALGQI-APNMTLPSVDLIAHPLPEAPPKTSTPTPPQRPISVPTAAALKMGVGFP 546
            .|.:..:.:...||:| ...:.:|::  :..|....|.|                   |.|
Mouse   667 KLRSEGQGIWALLGRITGQKLNVPAI--LRAPKERKPSK-------------------KEG---- 706

  Fly   547 LGHLGPPGSKMDSSRMLSTHAKQGKHSTSSASVEAAPSV--SCGICKRSKDQHLLVKCDTCNLHY 609
                                   |...||     |.|:|  ||||||::.|||||:.||||.|||
Mouse   707 -----------------------GTQKTS-----ALPTVLYSCGICKKNHDQHLLLLCDTCKLHY 743

  Fly   610 HLGCLNPPLTRPPKKSKQYGWQCSECCDKSEGSDAVTEISSGPRKSRTRFNKDGHLVYVDRYSLD 674
            |||||:|||||.|:|:|...||||| ||::..||...|:
Mouse   744 HLGCLDPPLTRMPRKTKNSYWQCSE-CDQAGSSDMEAEM-------------------------- 781

  Fly   675 DIPVAAVNVPKESHTKRALNKSLPAPAPEYIEDLTKSPKRPKLQSPCK-TPINVPAENVTPTTDA 738
                                      |.|.:.|.||..:| :::.|.| .|.:||
Mouse   782 --------------------------AMETLPDGTKRSRR-QIKEPVKFVPQDVP---------- 809

  Fly   739 APVAASAATPAAAPTLPTPNTIVINLSGCEDSIDDSSGKLSRKGKRKDKHKNKHNLSSDTEKSIG 803
                            |.|..|.|
Mouse   810 ----------------PEPKKIPI----------------------------------------- 817

  Fly   804 KEHKRKRKKRAHLDESSTHLDNAGNTSGSTIKIIFKALRLPGEDAPESQYFYVPANAVRSVDEAS 868
            :..:.:.:||:.:.|...|
Mouse   818 RNTRTRGRKRSFVPEEEKH---------------------------------------------- 836

  Fly   869 RPTSVETVEDSVQGAEQALAPIVLPAASPQKVREPKETAASASVNPTPSPKRKVSPRKASPRKPR 933
                                          :.|.|:|                           |
Mouse   837 ------------------------------EERVPRE---------------------------R 844

  Fly   934 VGRPRVSNAKPNVE---ISCCVCSQTGKSNQVVTCDECHRHYHFACLDPPLKKSPKIRGYSWHCA 995
            ..|..|...||..|   ..|..|..||.:..:|.||||...|||.|||||||||||..||.|.|.
Mouse   845 RQRQSVLQKKPKAEDLRTECSTCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQ 909

  Fly   996 DCDPTDEDALPKK 1008
            :||.:....:|.:
Mouse   910 ECDSSSSKTIPSR 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15439	NP_608836.1	PHD1_PHF14	120..175	CDD:277036	33/55 (60%)
		ePHD_PHF14	184..297	CDD:277144	78/112 (70%)
		PHD2_PHF14	586..635	CDD:277037	35/48 (73%)
		PRK10819	854..>938	CDD:236768	5/83 (6%)
		PHD3_PHF14	949..997	CDD:277038	27/47 (57%)
Phf14	XP_006505259.1	PHD1_PHF14	314..370	CDD:277036	33/55 (60%)
		ePHD_PHF14	378..491	CDD:277144	78/112 (70%)
		PHD2_PHF14	720..769	CDD:277037	36/49 (73%)
		PHD3_PHF14	863..911	CDD:277038	27/47 (57%)