Protein Alignment CG15439 and phf14

DIOPT Version :10

• Sequence 1: NP_608836.1
• Gene: CG15439 / 33651
• FlyBaseID: FBgn0031606
• Length: 1008
• Species: Drosophila melanogaster
• Sequence 2: NP_001410702.1
• Gene: phf14 / 555505
• ZFINID: ZDB-GENE-030131-1796
• Length: 914
• Species: Danio rerio
• Alignment Length: 1047
• Identity: 318/1047 - (30%)
• Similarity: 445/1047 - (42%)
• Gaps: 338/1047 - (32%)

  Fly     3 RARQPKI---TTQALLDFDLGESSSDSDFLP--------------------DIDNCSDGSKDESD 44
            |..:|.:   |.:.|.:.|..:|..|:|:.|                    :.|:..||..||.|
Zfish   142 RRNRPMLDFTTMEELNEMDDYDSEDDNDWRPTQGKKKGKASSGKEKEGSGEEDDDDDDGGSDEED 206

  Fly    45 G-----DGSSSDASGGSDSESDSDAESEDSTLQLRQ-----LLAETEPSPLENGINGVDHCAASS 99
            .     |....|..|..|..|.||:|.|....:.:.     ...|.|    .|..:...|...:.
Zfish   207 NEDDNDDDDDDDDEGNDDESSSSDSEEEGKKPKKKAGKNTGAFDEEE----TNDSHSTSHGKGNE 267

  Fly   100 PAAPVVPRAPLQLSSAPAKRM-----CCVCLGERSDDVNEIVECDSCGVSVHEGCYGV-SDNVSI 158
            .:   :...|...||   :||     ||||||:.|:|.:||::||:|||:|||||||| .::.||
Zfish   268 DS---LLERPQTWSS---QRMEHILICCVCLGDNSEDADEIIQCDNCGVTVHEGCYGVDGESDSI 326

  Fly   159 SSTNSTCSTEPWFCEACRAGVSEPDCELCPNKGGIYKETDVGKWVHLICALYVPGVAFGEVEQLS 223
            .|:.|..|||||||:||:.||| |.|||||::.||:||||.|:|||::|||||||||||::::|.
Zfish   327 MSSASENSTEPWFCDACKNGVS-PSCELCPSQDGIFKETDAGRWVHVVCALYVPGVAFGDIDKLR 390

  Fly   224 SVTLFEMQYSKWGAKVCSLCENALFARTGVCIGCDAGMCKTYFHVTCAQVAGFLIEAHHEDDAAD 288
            .|||.||.|||:|||.|||||:..||||||||.||||||:::|||||||..|.|.||..|:|.||
Zfish   391 PVTLTEMNYSKYGAKECSLCEDTRFARTGVCISCDAGMCRSFFHVTCAQREGLLSEAAAEEDIAD 455

  Fly   289 PFYAHCKVHSEKEMIKKRRRNYHTLR--LNMMQRAREKEALAAEHETPAPHPNPAQARIQRKLLK 351
            ||:|:||.|:::...|.:|:||..|:  ..:..:.|||:.      ||     .|||||..:|.:
Zfish   456 PFFAYCKQHADRFDRKWKRKNYLALQSYCKVSLQEREKQL------TP-----EAQARITTRLQQ 509

  Fly   352 IQHKYTRHKELKPTPWVPTQKMSRLLTTSASACRRLLAKAEIMSVDVQHLEQREAHINALTDIRK 416
            .:.|....:..:|..|||.:|:.|.||:||||.|:|:.|||:|.:.........:.|:|..|.|:
Zfish   510 YRAKAELSRNTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDTSDISASVDGRR 574

  Fly   417 KWHIAPAFSVEFTAYYMDRIVRMDDFRQQQRELISHNAILSKDQDVLRAQYDTALEERKAVKATK 481
            | |..||.:.:|..||::|.:||...:....|..:....|..:|:.|..:||...|..:.::...
Zfish   575 K-HKQPALTADFVNYYLERNMRMIQIQDNIVEQKNLKDKLESEQEKLHMEYDKLCESLEDLQNVN 638

  Fly   482 DSLLTSIKSLHTALGQI-APNMTLPSVDLIAHPLPEAPPKTSTPTPPQRPISVPTAAALKMGVGF 545
            ..|.|..:|:.:.:|.| ...:.:|:|  :..|....|.|                   |.|
Zfish   639 GQLRTEGQSIWSMMGGIVGQKLNVPAV--LKAPKERKPSK-------------------KEG--- 679

  Fly   546 PLGHLGPPGSKMDSSRMLSTHAKQGKHSTSSASVEAAPSVSCGICKRSKDQHLLVKCDTCNLHYH 610
                 |.||.......||                     .||||||:::|||||:.||||.||||
Zfish   680 -----GSPGKSSSLPAML---------------------YSCGICKKNQDQHLLLLCDTCKLHYH 718

  Fly   611 LGCLNPPLTRPPKKSKQYGWQCSECCDKSEGSDAVTEISSGPRKSRTRFNKDGHLVYVDRYSLDD 675
            ||||:|||||.|||:|...||||||                                 |:.|.|:
Zfish   719 LGCLDPPLTRMPKKTKNSYWQCSEC---------------------------------DQASSDE 750

  Fly   676 IPVAAVNVPKESHTKRALNKSLPAPAPEYIEDLTKSPKRPKLQSPCKTPINVPAENVTPTTDAAP 740
            ..:|...:|  ..|||: .:.:..|.....::::..||:|:::
Zfish   751 ADIAMETLP--DGTKRS-RRQIKGPIKFIPQEMSPEPKKPQVR---------------------- 790

  Fly   741 VAASAATPAAAPTLPTPNTIVINLSGCEDSIDDSSGKLSRKGKRKDKHKNKHNLSSDTEKSIGKE 805
                                               |..:|..|||             ..||.:|
Zfish   791 -----------------------------------GTRTRGQKRK-------------RMSICEE 807

  Fly   806 HKRKRKKRAHLDESSTHLDNAGNTSGSTIKIIFKALRLPGEDAPESQYFYVPANAVRSVDEASRP 870
            .|.:.
Zfish   808 EKMEE------------------------------------------------------------ 812

  Fly   871 TSVETVEDSVQGAEQALAPIVLPAASPQKVREPKETAASASVNPTPSPKRKVSPRKASPRKPRVG 935
                                                         |.|:.:...:....:||:..
Zfish   813 ---------------------------------------------PLPRERRQRQSTLQKKPKAD 832

  Fly   936 RPRVSNAKPNVEISCCVCSQTGKSNQVVTCDECHRHYHFACLDPPLKKSPKIRGYSWHCADCDPT 1000
            ..|.         .|..|...|.:..:|.||||...|||.|||||||||||..||.|.|.:||.:
Zfish   833 DTRT---------ECTTCKGPGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDTS 888

  Fly  1001 ---DEDA 1004
               :|:|
Zfish   889 SSKEEEA 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15439	NP_608836.1	PHD1_PHF14	120..175	CDD:277036	35/60 (58%)
		ePHD_PHF14	184..297	CDD:277144	77/112 (69%)
		PHD2_PHF14	586..635	CDD:277037	36/48 (75%)
		PRK10819	854..>938	CDD:236768	4/83 (5%)
		PHD3_PHF14	949..997	CDD:277038	26/47 (55%)
phf14	NP_001410702.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..276		29/140 (21%)
		COG5141	<287..>619	CDD:227470	170/344 (49%)
		ePHD_PHF14	351..464	CDD:277144	77/112 (69%)
		PHD2_PHF14	694..743	CDD:277037	36/48 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	777..838		17/244 (7%)
		PHD3_PHF14	837..885	CDD:277038	26/47 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	887..914		2/9 (22%)