Protein Alignment CG15439 and Phf14

DIOPT Version :10

• Sequence 1: NP_608836.1
• Gene: CG15439 / 33651
• FlyBaseID: FBgn0031606
• Length: 1008
• Species: Drosophila melanogaster
• Sequence 2: XP_006236166.1
• Gene: Phf14 / 500030
• RGDID: 1563764
• Length: 950
• Species: Rattus norvegicus
• Alignment Length: 1064
• Identity: 317/1064 - (29%)
• Similarity: 439/1064 - (41%)
• Gaps: 379/1064 - (35%)

  Fly     9 ITTQALLDFDLGESSSDSDFLPDI---DNCSDGSKDESDGDGSSSDASGGSDSESDSDAESEDST 70
            ::.:.|.|.|..:|..|:|:.|.:   ...|...|:.||||....| ..||.||.|.:.|..|.
  Rat   187 VSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDD-DEGSGSEEDENDEGNDE- 249

  Fly    71 LQLRQLLAETEPSPLENGINGVDHCAASSPAAPV-------------------VPRAPLQLSSAP 116
                                  ||   ||||:..                   :....|.||.:.
  Rat   250 ----------------------DH---SSPASEAGGKKKKSKVLSRNSADDEELTNDSLTLSQSK 289

  Fly   117 AKR--------------------MCCVCLGERSDDVNEIVECDSCGVSVHEGCYGV-SDNVSISS 160
            :..                    :||||||:.|:|.:||::||:||::|||||||| .::.||.|
  Rat   290 SNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMS 354

  Fly   161 TNSTCSTEPWFCEACRAGVSEPDCELCPNKGGIYKETDVGKWVHLICALYVPGVAFGEVEQLSSV 225
            :.|..|||||||:||:.||| |.||||||:.||:||||.|:|||::|||||||||||::::|..|
  Rat   355 SASENSTEPWFCDACKCGVS-PSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPV 418

  Fly   226 TLFEMQYSKWGAKVCSLCENALFARTGVCIGCDAGMCKTYFHVTCAQVAGFLIEAHHEDDAADPF 290
            ||.||.|||:|||.||.||:..||||||||.||||||:.||||||||..|.|.||..|:|.||||
  Rat   419 TLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPF 483

  Fly   291 YAHCKVHSEKEMIKKRRRNYHTLR--LNMMQRAREKEALAAEHETPAPHPNPAQARIQRKLLKIQ 353
            :|:||.|:::...|.:|:||..|:  ..|..:.|||: |:.|          |||||..:|.:.:
  Rat   484 FAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQ-LSPE----------AQARINARLQQYR 537

  Fly   354 HKYTRHKELKPTPWVPTQKMSRLLTTSASACRRLLAKAEIMSVDVQHLEQREAHINALTDIRKKW 418
            .|....:..:|..|||.:|:.|.||:||||.|:|:.|||:|.:.........:..::..|.|:|
  Rat   538 AKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRK- 601

  Fly   419 HIAPAFSVEFTAYYMDRIVRMDDFRQQQRELISHNAILSKDQDVLRAQYDTALEERKAVKATKDS 483
            |..||.:.:|..||.:|.:||...::...|..:....|..:|:.|..:|:...|..:.::.....
  Rat   602 HKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGK 666

  Fly   484 LLTSIKSLHTALGQI-APNMTLPSVDLIAHPLPEAPPKTSTPTPPQRPISVPTAAALKMGVGFPL 547
            |.:..:.:...||:| ...:.:|::  :..|....|.|....|  |:..|:||..
  Rat   667 LRSEGQGIWALLGRITGQKLNVPAI--LRAPKERKPSKKEGGT--QKTSSLPTVL---------- 717

  Fly   548 GHLGPPGSKMDSSRMLSTHAKQGKHSTSSASVEAAPSVSCGICKRSKDQHLLVKCDTCNLHYHLG 612
                                                 .||||||::.|||||:.||||.||||||
  Rat   718 -------------------------------------YSCGICKKNHDQHLLLLCDTCKLHYHLG 745

  Fly   613 CLNPPLTRPPKKSKQYGWQCSECCDKSEGSDAVTEISSGPRKSRTRFNKDGHLVYVDRYSLDDIP 677
            ||:|||||.|:|:|...||||| ||::..||...|:
  Rat   746 CLDPPLTRMPRKTKNSYWQCSE-CDQAGSSDMEAEM----------------------------- 780

  Fly   678 VAAVNVPKESHTKRALNKSLPAPAPEYIEDLTKSPKRPKLQSPCK-TPINVPAENVTPTTDAAPV 741
                                   |.|.:.|.||..:| :::.|.| .|.:||
  Rat   781 -----------------------AMETLPDGTKRSRR-QIKEPVKFVPQDVP------------- 808

  Fly   742 AASAATPAAAPTLPTPNTIVINLSGCEDSIDDSSGKLSRKGKRKDKHKNKHNLSSDTEKSIGKEH 806
                         |.|..|.|                                         :..
  Rat   809 -------------PEPKKIPI-----------------------------------------RNT 819

  Fly   807 KRKRKKRAHLDESSTHLDNAGNTSGSTIKIIFKALRLPGEDAPESQYFYVPANAVRSVDEASRPT 871
            :.:.:||:.:.|...|
  Rat   820 RTRGRKRSFVPEEEKH------------------------------------------------- 835

  Fly   872 SVETVEDSVQGAEQALAPIVLPAASPQKVREPKETAASASVNPTPSPKRKVSPRKASPRKPRVGR 936
                                       :.|.|:|                           |..|
  Rat   836 ---------------------------EERVPRE---------------------------RRQR 846

  Fly   937 PRVSNAKPNVE---ISCCVCSQTGKSNQVVT----------CDECHRHYHFACLDPPLKKSPKIR 988
            ..|...||..|   ..|..|..||::..:|:          ||||...|||.|||||||||||..
  Rat   847 QSVLQKKPKAEDLRTECSTCKGTGENENLVSRMRLSEAKNRCDECRLCYHFGCLDPPLKKSPKQT 911

  Fly   989 GYSWHCADCDPT----DEDALPKK 1008
            ||.|.|.:||.:    ||:...||
  Rat   912 GYGWICQECDSSSSKEDENEAGKK 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15439	NP_608836.1	PHD1_PHF14	120..175	CDD:277036	33/55 (60%)
		ePHD_PHF14	184..297	CDD:277144	78/112 (70%)
		PHD2_PHF14	586..635	CDD:277037	35/48 (73%)
		PRK10819	854..>938	CDD:236768	5/83 (6%)
		PHD3_PHF14	949..997	CDD:277038	27/57 (47%)
Phf14	XP_006236166.1	PHD1_PHF14	313..369	CDD:277036	33/55 (60%)
		ePHD_PHF14	377..490	CDD:277144	78/112 (70%)
		PHD2_PHF14	719..768	CDD:277037	36/49 (73%)
		PHD3_PHF14	862..920	CDD:277038	27/57 (47%)