Protein Alignment CG15439 and LOC1272343

DIOPT Version :10

• Sequence 1: NP_608836.1
• Gene: CG15439 / 33651
• FlyBaseID: FBgn0031606
• Length: 1008
• Species: Drosophila melanogaster
• Sequence 2: XP_311289.6
• Gene: LOC1272343 / 1272343
• VectorBaseID: AGAMI1_000438
• Length: 1208
• Species: Anopheles gambiae
• Alignment Length: 1242
• Identity: 501/1242 - (40%)
• Similarity: 639/1242 - (51%)
• Gaps: 282/1242 - (22%)

  Fly     1 MKRARQPK----ITTQALLDFDLGESSSDSDFL----PDIDNCSDGSKDESDGDGSSSDASGGSD 57
            :||.|...    :|||.|||||||||||||||.    .:.|:||.||||:.|.||...|.....|
Mosquito     5 VKRRRASSGGGGLTTQTLLDFDLGESSSDSDFRIEDHDESDDCSLGSKDDGDDDGDDDDDDEDED 69

  Fly    58 SESDSDA------ESEDS------TLQLRQLL----------AETEPSPLENGINGVDHCAASSP 100
            .:.|.::      :|||:      :..|.|||          .|.:.|..|.|       ...:.
Mosquito    70 DDDDDESGDDSGDDSEDNGEAGAGSNPLLQLLHGAQNGGGNEEEEDESTTEGG-------GGQAK 127

  Fly   101 AAPVVPRAPLQLSSAPA-------KRMCCVCLGERSDDVNEIVECDSCGVSVHEGCYGVSDNVSI 158
            ..|.||.|. |.|...|       |.:||.|||:||||.|||||||.|||:|||||||||:..|:
Mosquito   128 GRPPVPAAK-QTSERDAALQKLLMKSICCACLGDRSDDQNEIVECDGCGVTVHEGCYGVSECTSV 191

  Fly   159 SSTNSTCSTEPWFCEACRAGVSEPDCELCPNKGGIYKETDVGKWVHLICALYVPGVAFGEVEQLS 223
            :||.|:||||||||:||:|||..||||||||||||:||||||:||||:|||||||||||||:|||
Mosquito   192 TSTISSCSTEPWFCDACKAGVENPDCELCPNKGGIFKETDVGRWVHLVCALYVPGVAFGEVDQLS 256

  Fly   224 SVTLFEMQYSKWGAKVCSLCENALFARTGVCIGCDAGMCKTYFHVTCAQVAGFLIEAHHED-DAA 287
            |||||||.|:|||||.|.|||:|..||||||||||||||||||||||||..|.|.|||.|: |.|
Mosquito   257 SVTLFEMPYNKWGAKTCCLCEDAQLARTGVCIGCDAGMCKTYFHVTCAQYYGLLSEAHSEEADQA 321

  Fly   288 DPFYAHCKVHSEKEMIKKRRRNYHTLRLNMMQRAREKEALAAEHETPAPHPNPAQARIQRKLLKI 352
            ||||||||:||:|.:||.|:|||:|:|:..:||..|:|....:      .|...|.||:|||.|.
Mosquito   322 DPFYAHCKIHSDKSLIKHRKRNYNTIRMRAVQRQVEEEGRRQQ------KPTAEQVRIERKLTKH 380

  Fly   353 QHKYTRHKELKPTPWVPTQKMSRLLTTSASACRRLLAKAEIMSVDVQHLEQREAHINALTDIRKK 417
            :.:|..:||.|..||||||||.|||.|||:||::||.|||:|.:|...:|.:||.:.:|.|:|||
Mosquito   381 RRRYVANKETKNPPWVPTQKMPRLLITSATACKKLLYKAELMGLDRAAIEFQEAQVASLADVRKK 445

  Fly   418 WHIAPAFSVEFTAYYMDRIVRMDDFRQQQRELISHNAILSKDQDVLRAQYDTALEERKAVKATKD 482
            |||.|||||||..||:||.:|::|.::..:|.::.|..|...|..||.:||.|:.:.:|.:...|
Mosquito   446 WHIPPAFSVEFIGYYLDRALRLEDMKKNLQEQMALNQRLLGKQQHLRNRYDQAVAQSQAAQKAND 510

  Fly   483 SLLTSIKSLHTALGQIAPNMTLPSVDLI------------AHPLPEAPPKTSTP----------- 524
            ::..||..|:..:|.:.|:..|..|:.|            |.|.|..||..:.|
Mosquito   511 AVRASIARLYEHIGALCPSKALVPVEQIGKPPAPVPAAMTAPPPPPPPPPIAQPAQPPAPPPEAA 575

  Fly   525 ------------------------------TPPQRPISVPTAAALKMGVGFPLGHLGPPGSKMDS 559
                                          |||.|.:||||||||||||||||.:|..||.:.|:
Mosquito   576 TAAASAPPAPPPPYVKPHQSVVINTGPLGATPPARTMSVPTAAALKMGVGFPLQNLMVPGKRDDT 640

  Fly   560 SRMLSTHAKQGKHSTSSASVEAAPSVSCGICKRSKDQHLLVKCDTCNLHYHLGCLNPPLTRPPKK 624
            .|:|||..||......:         .||||||..|||||.|||||:||||||||||||||.|||
Mosquito   641 GRILSTQCKQNSEELLN---------ECGICKRCHDQHLLAKCDTCHLHYHLGCLNPPLTRHPKK 696

  Fly   625 SKQYGWQCSECCDKSEGSDAVTEISSGPRKSRTRFNKDGHLVYVD-------------------- 669
            ||.||||||||....:.:.....|...|||||||::|||.:|..|
Mosquito   697 SKLYGWQCSECDQSDDSNPESIIIPKAPRKSRTRYSKDGTIVPYDYAFPPDTQPQAVEAVGRRAS 761

  Fly   670 -----RYSLDDIPVA-----AVN-VPKESHTKR----------ALNKSLPAPAPEYIEDLT---- 709
                 ...:.|.|||     ||: :|.::..||          |:.::..|.|...|...|
Mosquito   762 RAGPVAVEVKDEPVAESTNEAVDPLPVKTPGKRGRKKKSLEGVAVGETTTAAAAAAITAATNLAT 826

  Fly   710 ----KSPKRPKLQSPCKTPINVPAE-------------------------NVTP----TTDA--- 738
                |..|:.|.:|..|.|....|.                         |.||    |:|.
Mosquito   827 AVQSKEVKQQKKKSDPKLPDGKDAADEELGEEEEEEARQSDEHSGKHSLLNTTPSELDTSDEQRA 891

  Fly   739 --------------------------------APVAASAATPAAAPT--LPTP----NTIVIN-- 763
                                            ||.|.|:...||...  ||.|    ..:..:
Mosquito   892 SEGGSSKMAKVESTTHHHHHHHHQHHHPGPPHAPTAGSSEATAAHTNAQLPAPEGSSEALAADGG 956

  Fly   764 ----------LSGCEDSIDDSSG-----KLSRKGKRKDKHKNKHNLSSDTEKSIGKEHKRKRKKR 813
                      :.|...|::|.:.     |.|:  :||:||:|:   |.:.::.|.|:||||||::
Mosquito   957 GDGGREPPGAMGGLPASVEDGAATSTHHKHSK--RRKEKHRNR---SPNADRPISKDHKRKRKRK 1016

  Fly   814 AH----LDESST---HLDNAGNTSGSTIKIIFKALRLPGEDAPESQYFYVPANAVRSVDEASRPT 871
            .|    :|::..   .|...|: |...|||..|:: |.|.:...:|.:|     ||:..:...|.
Mosquito  1017 NHDYETVDQTELVEYPLPEYGD-SRPRIKIKIKSV-LDGSNTHTTQIYY-----VRTEPQEEEPA 1074

  Fly   872 SVETVEDSVQGAEQA-------LAPIVLPAASPQKVREPKETAASASVNPTPSPKRKVSPRKASP 929
            ..:....:...:.||       |.|.:.|||......|...|.......    .||.|..|..:.
Mosquito  1075 EPQLTSGAADSSSQAGPLMSHPLLPQLQPAAQFNGSTEQTITITQGRAR----VKRDVGSRHNAS 1135

  Fly   930 RKPRVGRPRVSNAKPNVEISCCVCSQTGKSNQVVTCDECHRHYHFACLDPPLKKSPKIRGYSWHC 994
            ....:|....|:...  |..|.||...|.|..:|.||||.:.|||.||:|||||:||.|||||||
Mosquito  1136 STTSIGSSVGSSGSD--ECICDVCQGVGTSANIVQCDECQKSYHFGCLEPPLKKTPKRRGYSWHC 1198

  Fly   995 ADCDPTD 1001
            |||||||
Mosquito  1199 ADCDPTD 1205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15439	NP_608836.1	PHD1_PHF14	120..175	CDD:277036	40/54 (74%)
		ePHD_PHF14	184..297	CDD:277144	94/113 (83%)
		PHD2_PHF14	586..635	CDD:277037	41/48 (85%)
		PRK10819	854..>938	CDD:236768	18/90 (20%)
		PHD3_PHF14	949..997	CDD:277038	30/47 (64%)
LOC1272343	XP_311289.6	None