Protein Alignment MFS18 and SLC17A9

DIOPT Version :9

• Sequence 1: NP_608835.1
• Gene: MFS18 / 33650
• FlyBaseID: FBgn0025684
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_071365.4
• Gene: SLC17A9 / 63910
• HGNCID: 16192
• Length: 436
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 167/424 - (39%)
• Similarity: 260/424 - (61%)
• Gaps: 12/424 - (2%)

  Fly    16 DTQSIWTRHEKRVWFITLITGTCMLYSTRTTMPLLVPAVASAQKWSKTDSGTVLSSFFWGYTLTQ 80
            |||  |:|.|.:.|..||:.|||:||..|::||:...:::....|:|.::|.|||||||||.|||
Human    15 DTQ--WSRPECQAWTGTLLLGTCLLYCARSSMPICTVSMSQDFGWNKKEAGIVLSSFFWGYCLTQ 77

  Fly    81 VVGGYFSDRFGGQRVILFAAIGWSLITFLMPTIIWTAGSIKSYAIPFIVAIRILNGALQGVHFPS 145
            ||||:..||.||::|||.:|..|..||.:.|.:    ..:.|..:.|:...|||.|.||||:||:
Human    78 VVGGHLGDRIGGEKVILLSASAWGSITAVTPLL----AHLSSAHLAFMTFSRILMGLLQGVYFPA 138

  Fly   146 MISLTSQNLCPNERSSFFGLLTAGSALGTLLTGIMGSFLLDYFGWSYVFRVIGLMGIAWA-LVLR 209
            :.||.||.:..:||:..:.::.|||..||||||.:||.||:::||..:|...|.:.:.|. .|.|
Human   139 LTSLLSQKVRESERAFTYSIVGAGSQFGTLLTGAVGSLLLEWYGWQSIFYFSGGLTLLWVWYVYR 203

  Fly   210 YYAMAGERNRIINIATPSRLCANKSPAETSAVPWLRYFRRLSFWACVLTHACEMNCFFVLLSWLP 274
            |  :..|::.|:.:..   |..::..:..:.|||.|.||:.:.||.|::.......||:||||||
Human   204 Y--LLSEKDLILALGV---LAQSRPVSRHNRVPWRRLFRKPAVWAAVVSQLSAACSFFILLSWLP 263

  Fly   275 TYFHDGFPHAKGWVVNMIPWLALPPCTLFAKYLTTRLLAREWHTTTVRKVIQSCCFAAQNLALFV 339
            |:|.:.||.||||:.|::|||...|.:||:.:|:..|:.:.:...||||::|.......::....
Human   264 TFFEETFPDAKGWIFNVVPWLVAIPASLFSGFLSDHLINQGYRAITVRKLMQGMGLGLSSVFALC 328

  Fly   340 MSRTSDFHTALICMTIIIGGTGFHNNAVTVNPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHI 404
            :..||.|..:::..:..||...|:::.::||.|||||..:|.:||:.||.||:.|.:||.|.|::
Human   329 LGHTSSFCESVVFASASIGLQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLGGYL 393

  Fly   405 LELTQSWPMVFSAAAGINLVGWIIFIVFGSAEAI 438
            :|.|.||..:|:..|.|:.:|...|:|||.|:.:
Human   394 METTGSWTCLFNLVAIISNLGLCTFLVFGQAQRV 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS18	NP_608835.1	MFS	30..432	CDD:119392	156/402 (39%)
		MFS_1	32..397	CDD:284993	143/365 (39%)
SLC17A9	NP_071365.4	MFS_1	44..386	CDD:311564	135/350 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152379
Domainoid	1	1.000	282	1.000	Domainoid score	I1666
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76562
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2485
Isobase	1	0.950	-	0	Normalized mean entropy	S4312
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D357187at33208
OrthoFinder	1	1.000	-	-		FOG0005560
OrthoInspector	1	1.000	-	-		oto91197
orthoMCL	1	0.900	-	-		OOG6_107359
Panther	1	1.100	-	-	LDO	PTHR11662
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3559
SonicParanoid	1	1.000	-	-		X3977
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750