DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS18 and MFS9

DIOPT Version :9

Sequence 1:	NP_608835.1	Gene:	MFS18 / 33650	FlyBaseID:	FBgn0025684	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	462	Identity:	123/462 - (26%)
Similarity:	213/462 - (46%)	Gaps:	57/462 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ELVDTQSI-WTRHEKRVWFITLIT--GTCMLYSTRTTMPLLVPAV------------ASAQK--- 59
            |:.:::.: |....|:.:.:.|:.  |...:||.|..:.:.:.|:            .|.|:
  Fly    22 EITESEPLTWRFWRKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQQDFP 86

  Fly    60 WSKTDSGTVLSSFFWGYTLTQVVGGYFSDRFGGQRVILFAAIG-WSLITFLMPTIIWTAGSIKSY 123
            |.....|.:|||||:||.|||.:|||...:.|| .::....|| .:::|.|.|       ...|:
  Fly    87 WDSKQKGLILSSFFYGYILTQFLGGYIGTKIGG-NIVFGTGIGSTAILTLLTP-------MAASH 143

  Fly   124 AIPFIVAIRILNGALQGVHFPSMISLTSQNLCPNERSSFFGLLTAGSALGTLLTGIMGSFLLDYF 188
            ::...:.:||:.|..:||.||.:.::.::...|.|||....:..||:..||::......||...:
  Fly   144 SLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKY 208

  Fly   189 GWSYVFRVIGLMGIAWALVLRYYAMAGERNRIINIATPSRLCANKSPAETSAV------------ 241
            ||..||.|.|.:|:.|.:....:..||..        ..|.|   |..|...:
  Fly   209 GWESVFYVFGTIGVIWYITWLVFVKAGPE--------LDRFC---SKEECDYIQKTIGYVGSKHV 262

  Fly   242 --PWLRYFRRLSFWACVLTHACEMNCFFVLLSWLPTYFHD--GFPHAKGWVVNMIPWLALPPCTL 302
              ||...|..:.|:|.:.:|..|...|:.||:.||::..|  .|...|..:::.:|:||:.....
  Fly   263 KHPWRAIFTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLA 327

  Fly   303 FAKYLTTRLLARE-WHTTTVRKVIQSCCFAAQNLALFVMSRTSDFHTALICMTIIIGGTGFHNNA 366
            .:.||...|..:. |.||.||:......|.||.:.:.:.:...|...:::.:||.:|...|..:.
  Fly   328 VSGYLADWLQVKGIWTTTQVRRNFNCGAFLAQTVFMMLTAYLLDPTWSVVSLTIAVGLGAFAWSG 392

  Fly   367 VTVNPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHIL--ELTQSWPMVFSAAAGINLVGWIIF 429
            ..||..|:||.|:..:.|:.||...|||.:...|.|:::  :.:..|.::|..:|||.|||.:|:
  Fly   393 FAVNHLDIAPQHASVLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVGCVIY 457

  Fly   430 IVFGSAE 436
            ..:.|.:
  Fly   458 WFYCSGD 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS18	NP_608835.1	MFS	30..432	CDD:119392	119/438 (27%)
MFS18	NP_608835.1	MFS_1	32..397	CDD:284993	108/399 (27%)
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	120/446 (27%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	119/436 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.960