Protein Alignment MFS18 and cima-1

DIOPT Version :9

• Sequence 1: NP_608835.1
• Gene: MFS18 / 33650
• FlyBaseID: FBgn0025684
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001294208.1
• Gene: cima-1 / 24104589
• WormBaseID: WBGene00018473
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 112/459 - (24%)
• Similarity: 175/459 - (38%)
• Gaps: 92/459 - (20%)

  Fly    30 FITL--------ITGTCMLYSTRTTMPLLVPAVASAQKWSKTDSGTVLSSFFWGYTLTQVVGGYF 86
            ||||        :...||     |:.|  |.......:|.....|.||::...| :|..:|.|.:
 Worm    78 FITLSISSSNLAVALICM-----TSCP--VHGYGGTLEWQSQQEGLVLAAQNAG-SLIMIVTGMW 134

  Fly    87 SDRFGGQRVI----LFAAIGWSLITFLMPTIIWTAGSIKSYAIPFIVAIRILNGALQGVHFPSMI 147
            :||..|:.::    |...||..::..|.....|           |.|..||..||......|::.
 Worm   135 ADRLNGKWMVFIGLLLCCIGNLMLPLLASKSFW-----------FAVLARISIGASDACLMPAVN 188

  Fly   148 SLTSQNLCPNERSSFFGLLTAGSALGTLLTGIMGSFL------LDYFGWSYVFRVIGLMGIAWAL 206
            ||.::.....||.:..||::.|..:|||.......:|      ||  ||..:|.:...:.:   |
 Worm   189 SLITRWFPQAERPAAIGLISGGRQIGTLFILPTAGYLCTRKDILD--GWPAIFYLSATISV---L 248

  Fly   207 VLRYYAMAGERNRIINIATPSR---------LCAN--KSPAETSAVPWLRYFRRLSFWACVLTHA 260
            |..::...|.......|...||         .|.:  |....|..||:.........|||:....
 Worm   249 VTVFWIPFGADKPAKQICISSREKEFIETRIACESIGKRTDRTRRVPYGAMLHSKPLWACIFALI 313

  Fly   261 CEMNCFFVLLSWLPTYFHD--GFPHAKGWVVNMIPWLALPPCTLF----AKYLTTRLLAREWHTT 319
            |......::|.:||.|..|  .|...|..::..:|.|.|.....|    :.||||:|   ....|
 Worm   314 CHEYPLVIMLQFLPNYMRDVLEFAPTKNGIIAALPILCLFLSKTFSSSLSSYLTTKL---RLDKT 375

  Fly   320 TVRKVIQSCCFAAQNLALFV-----MSRTSDFHTALICMTIIIGGTGFHNNAVTVNPQDLAPLHS 379
            .|.|...:  .|:..||:.:     .::.|.| .|:.|:...:...|.|...|......:||..|
 Worm   376 FVCKGFNA--VASAGLAICISFVPFFNKESAF-LAVFCLCGAMIFAGLHTPGVITAMVQIAPAFS 437

  Fly   380 GSV----------FGLMNTVGAIPGFLGVYL--AGHILELTQSWPMVFSAAAGINLVGWIIFIVF 432
            |.:          |.:.|.:      |..|:  :|.:.|    |.|||..:|.:..:..|:|.::
 Worm   438 GIITGWSFFAVAWFSIGNKI------LTKYIVQSGSVTE----WGMVFRVSALVAALPVIVFTIW 492

  Fly   433 GSAE 436
            |||:
 Worm   493 GSAD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS18	NP_608835.1	MFS	30..432	CDD:119392	109/453 (24%)
		MFS_1	32..397	CDD:284993	96/414 (23%)
cima-1	NP_001294208.1	2A0114euk	63..506	CDD:129972	112/459 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4312
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760