Protein Alignment MFS18 and cima-1

DIOPT Version :10

• Sequence 1: NP_608835.1
• Gene: MFS18 / 33650
• FlyBaseID: FBgn0025684
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001294208.1
• Gene: cima-1 / 24104589
• WormBaseID: WBGene00018473
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 112/459 - (24%)
• Similarity: 175/459 - (38%)
• Gaps: 92/459 - (20%)

  Fly    30 FITL--------ITGTCMLYSTRTTMPLLVPAVASAQKWSKTDSGTVLSSFFWGYTLTQVVGGYF 86
            ||||        :...||     |:.|  |.......:|.....|.||::...| :|..:|.|.:
 Worm    78 FITLSISSSNLAVALICM-----TSCP--VHGYGGTLEWQSQQEGLVLAAQNAG-SLIMIVTGMW 134

  Fly    87 SDRFGGQRVI----LFAAIGWSLITFLMPTIIWTAGSIKSYAIPFIVAIRILNGALQGVHFPSMI 147
            :||..|:.::    |...||..::..|.....|           |.|..||..||......|::.
 Worm   135 ADRLNGKWMVFIGLLLCCIGNLMLPLLASKSFW-----------FAVLARISIGASDACLMPAVN 188

  Fly   148 SLTSQNLCPNERSSFFGLLTAGSALGTLLTGIMGSFL------LDYFGWSYVFRVIGLMGIAWAL 206
            ||.::.....||.:..||::.|..:|||.......:|      ||  ||..:|.:...:.:   |
 Worm   189 SLITRWFPQAERPAAIGLISGGRQIGTLFILPTAGYLCTRKDILD--GWPAIFYLSATISV---L 248

  Fly   207 VLRYYAMAGERNRIINIATPSR---------LCAN--KSPAETSAVPWLRYFRRLSFWACVLTHA 260
            |..::...|.......|...||         .|.:  |....|..||:.........|||:....
 Worm   249 VTVFWIPFGADKPAKQICISSREKEFIETRIACESIGKRTDRTRRVPYGAMLHSKPLWACIFALI 313

  Fly   261 CEMNCFFVLLSWLPTYFHD--GFPHAKGWVVNMIPWLALPPCTLF----AKYLTTRLLAREWHTT 319
            |......::|.:||.|..|  .|...|..::..:|.|.|.....|    :.||||:|   ....|
 Worm   314 CHEYPLVIMLQFLPNYMRDVLEFAPTKNGIIAALPILCLFLSKTFSSSLSSYLTTKL---RLDKT 375

  Fly   320 TVRKVIQSCCFAAQNLALFV-----MSRTSDFHTALICMTIIIGGTGFHNNAVTVNPQDLAPLHS 379
            .|.|...:  .|:..||:.:     .::.|.| .|:.|:...:...|.|...|......:||..|
 Worm   376 FVCKGFNA--VASAGLAICISFVPFFNKESAF-LAVFCLCGAMIFAGLHTPGVITAMVQIAPAFS 437

  Fly   380 GSV----------FGLMNTVGAIPGFLGVYL--AGHILELTQSWPMVFSAAAGINLVGWIIFIVF 432
            |.:          |.:.|.:      |..|:  :|.:.|    |.|||..:|.:..:..|:|.::
 Worm   438 GIITGWSFFAVAWFSIGNKI------LTKYIVQSGSVTE----WGMVFRVSALVAALPVIVFTIW 492

  Fly   433 GSAE 436
            |||:
 Worm   493 GSAD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS18	NP_608835.1	MFS_SLC17A9_like	31..433	CDD:340938	108/453 (24%)
cima-1	NP_001294208.1	2A0114euk	63..506	CDD:129972	112/459 (24%)