DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS18 and Slc17a8

DIOPT Version :9

Sequence 1:	NP_608835.1	Gene:	MFS18 / 33650	FlyBaseID:	FBgn0025684	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_892004.1	Gene:	Slc17a8 / 216227	MGIID:	3039629	Length:	601	Species:	Mus musculus

Alignment Length:	431	Identity:	118/431 - (27%)
Similarity:	194/431 - (45%)	Gaps:	40/431 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GTCMLYSTRTTMPLLV--------------PAVASAQ-KWSKTDSGTVLSSFFWGYTLTQVVGGY 85
            |.|:.:..|..:.:.:              |.:.:|| .|.....|.:..||||||.:||:.||:
Mouse    98 GFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGF 162

  Fly    86 FSDRFGGQRVILFAAIGWSLITFLMPTIIWTAGSIKSYAIPFIVAIRILNGALQGVHFPSMISLT 150
            .|::|...|| ..|||      ||..|:.....|........::.:|||.|.::||.:|:...:.
Mouse   163 ISNKFAASRV-FGAAI------FLTSTLNMFIPSAARVHYGCVMGVRILQGLVEGVTYPACHGMW 220

  Fly   151 SQNLCPNERSSFFGLLTAGSALGTLLTGIMGSFLLDYFGWSYVFRVIGLMGIAWAL--VLRYYAM 213
            |:...|.|||........||..|.::...:...|:.|.||:.||.:.|:.||.|.:  :|:.|..
Mouse   221 SKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASVFYIYGMFGIIWYMFWLLQAYEC 285

  Fly   214 AGERNRIIN-----IATPSRLCANKSPAETSAVPWLRYFRRLSFWACVLTHACEMNCFFVLLSWL 273
            ......|.|     |.|.....||.:.......||.|:|..|..:|.::.:.|....|::||...
Mouse   286 PAAHPTISNAERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQ 350

  Fly   274 PTYFHD--GFPHAKGWVVNMIPWLAL----PPCTLFAKYLTTRLLAREWHTTTVRKVIQSCCFAA 332
            |.||.:  ||..:|..:::.:|.:.:    |.....|.||.:|.:..   ||.|||::....|..
Mouse   351 PAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILT---TTAVRKIMNCGGFGM 412

  Fly   333 QNLALFVMSRTSDFHTALICMTIIIGGTGFHNNAVTVNPQDLAPLHSGSVFGLMNTVGAIPGFLG 397
            :...|.|:..:.....|:..:.:.:|.:||..:...||..|:||.::..:.|:.|.||.:.|.:.
Mouse   413 EATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVC 477

  Fly   398 VYLAGHIL--ELTQSWPMVFSAAAGINLVGWIIFIVFGSAE 436
            ..:.|.:.  :..:.|..||..||.::..|.|.:.||.|.|
Mouse   478 PLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGE 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS18	NP_608835.1	MFS	30..432	CDD:119392	114/425 (27%)
MFS18	NP_608835.1	MFS_1	32..397	CDD:284993	106/388 (27%)
Slc17a8	NP_892004.1	2A0114euk	88..526	CDD:129972	118/431 (27%)
		MFS	93..515	CDD:119392	115/426 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	576..601
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820