Protein Alignment MFS18 and SLC17A3

DIOPT Version :10

• Sequence 1: NP_608835.1
• Gene: MFS18 / 33650
• FlyBaseID: FBgn0025684
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 97/422 - (22%)
• Similarity: 171/422 - (40%)
• Gaps: 64/422 - (15%)

  Fly    48 PLLVPAVASAQKWSKTDSGTVLSSFFWGYTLTQVVGGYFSDRFGGQRVILFAAIGWSLITFLMPT 112
            |..:||.|....||....|.:..:..:|..||....||.:.|.|.:||:..:....|.:|..:|.
Human    95 PKSLPAKAPVYDWSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFATSFLTLCIPL 159

  Fly   113 IIWTAGSIKSYAIPFIVAIRILNGALQGVHFPSMISLTSQNLCPNERSSFFGLLTAGSALGTLLT 177
                   ...:.|..::..||:.|..|........::..:...|.|||....:..:|..||....
Human   160 -------ATDFGIVLLIVTRIVQGLSQSSILGGQFAIWEKWGPPQERSRLCSIALSGMLLGCFTA 217

  Fly   178 GIMGSFLLDYFGWSYVFRVIGLMG----IAWALVL-----RY-YAMAGERNRIINIATPSRLCAN 232
            .::|.|:.:..||.:||.:.|.:|    :.|.:|:     .| :....|:..||: :...::.::
Human   218 ILIGGFISETLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIIS-SLKQQVGSS 281

  Fly   233 KSPAETSAVPWLRYFRRLSFWACVLTHACEMNCF------FVLLSWLPTY----FH--------- 278
            |.|....|:     .|.|..|:..|      .||      ..::.::|||    :|
Human   282 KQPLPIKAM-----LRSLPIWSICL------GCFSHQWLVSTMVVYIPTYISSVYHVNIRDNGLL 335

  Fly   279 DGFPHAKGWVVNMIPWLALPPCTLFAKYLTTRLLAREWHTTTVRKVIQSCCFAAQNLALFVM--S 341
            ...|....||:.|:           ..||...||.:::...|||| |.:...:..:.||.|.  .
Human   336 SALPFIVAWVIGMV-----------GGYLADFLLTKKFRLITVRK-IATILGSLPSSALIVSLPY 388

  Fly   342 RTSDFHTALICMTIIIGGTGFHNNAVTVNPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHILE 406
            ..|.:.||...:|:..|.:....:.:.:|..|:||.:|..:.|......:|...:...::|.:|.
Human   389 LNSGYITATALLTLSCGLSTLCQSGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLLS 453

  Fly   407 LTQ--SWPMVFSAAAGINLVGWIIFIVFGSAE 436
            ...  .|..||.....:||:|.:.:::||.|:
Human   454 QDPEFGWRNVFFLLFAVNLLGLLFYLIFGEAD 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS18	NP_608835.1	MFS_SLC17A9_like	31..433	CDD:340938	94/417 (23%)
SLC17A3	NP_001091956.1	MFS_SLC17	42..482	CDD:340876	94/417 (23%)