DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Elp3 and ELO3

DIOPT Version :9

Sequence 1:	NP_608834.1	Gene:	Elp3 / 33649	FlyBaseID:	FBgn0031604	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_568725.1	Gene:	ELO3 / 835098	AraportID:	AT5G50320	Length:	565	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	394/541 - (72%)
Similarity:	460/541 - (85%)	Gaps:	0/541 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GVGLSRQERQVLVIGEIIQELLKAHEAKKDVNLNRMKSLVASKYGLDSSPRLVDIIAAVPQDAKK 72
            |.||:.:|.:|..|.||:..:::.....::|:||.:|:....||||..:|:||::|||:|...::
plant    24 GRGLTEEEARVRAISEIVSTMIERSHRNENVDLNAIKTAACRKYGLARAPKLVEMIAALPDSERE 88

  Fly    73 ILLPKLRAKPIRTASGIAVVAVMCKPHRCPHINMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSM 137
            .|||||||||:||||||||||||.||||||||..|||||||||||||||||||||||||||||||
plant    89 TLLPKLRAKPVRTASGIAVVAVMSKPHRCPHIATTGNICVYCPGGPDSDFEYSTQSYTGYEPTSM 153

  Fly   138 RAIRSRYDPFLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMCLPEEYRDYFIRNLHDALSGHSSAN 202
            ||||:||:|::|.|.|::|||:|||||||||||:||||||.||.||||:||||||||||||:|||
plant   154 RAIRARYNPYVQARSRIDQLKRLGHSVDKVEFILMGGTFMSLPAEYRDFFIRNLHDALSGHTSAN 218

  Fly   203 VAEAVRYSEKSRTKCIGITIETRPDYCLKRHISDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVR 267
            |.|||.|||.|.|||||:||||||||||..|:..||.||||||||||||.||||||||||||||.
plant   219 VEEAVAYSEHSATKCIGMTIETRPDYCLGPHLRQMLIYGCTRLEIGVQSTYEDVARDTNRGHTVA 283

  Fly   268 AVCESFQLGKDAGYKIVTHMMPDLPNVDFERDIEQFIEYFENPAFRSDGLKIYPTLVIRGTGLYE 332
            ||.:.|.|.||||:|:|.|||||||||..|||:|.|.|:||:|:||:||||||||||||||||||
plant   284 AVADCFCLAKDAGFKVVAHMMPDLPNVGVERDMESFKEFFESPSFRADGLKIYPTLVIRGTGLYE 348

  Fly   333 LWKTGRYKSYPPSMLVDLVAKILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLG 397
            |||||||::|||..|||:||:||::|||||||||||||||||||:||||.|||||||||||.|||
plant   349 LWKTGRYRNYPPEQLVDIVARILSMVPPWTRVYRVQRDIPMPLVTSGVEKGNLRELALARMDDLG 413

  Fly   398 TTCRDVRTREVGIQEIHNKVRPYEIELIRRDYVANGGWETFLSYEDPEQDILVGLLRLRKCSPDT 462
            ..||||||||.|||:||:|::|.::||:||||.||.||||||||||..|||||||||||||..:.
plant   414 LKCRDVRTREAGIQDIHHKIKPEQVELVRRDYTANEGWETFLSYEDTRQDILVGLLRLRKCGKNV 478

  Fly   463 FRPELKGECSIVRELHVYGSVVPVNARDPTKFQHQGFGMLLMEEAERIAREEHGSTKLAVISGVG 527
            ..|||.|:||:||||||||:.|||:.||..|.||||:|.|||||||||||.||.|.|:.||||||
plant   479 TCPELMGKCSVVRELHVYGTAVPVHGRDADKLQHQGYGTLLMEEAERIARREHRSNKIGVISGVG 543

  Fly   528 TRNYYRKMGYQLDGPYMSKSI 548
            ||:||||:||:|:||||.|.:
plant   544 TRHYYRKLGYELEGPYMVKHL 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elp3	NP_608834.1	ELP3	23..548	CDD:273503	388/524 (74%)
ELO3	NP_568725.1	ELP3	39..564	CDD:273503	388/524 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	324	1.000	Domainoid score	I271
eggNOG	1	0.900	-	-		E1_COG1243
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7105
Inparanoid	1	1.050	828	1.000	Inparanoid score	I76
OMA	1	1.010	-	-		QHG62148
OrthoDB	1	1.010	-	-		D320059at2759
OrthoFinder	1	1.000	-	-		FOG0003595
OrthoInspector	1	1.000	-	-		oto3605
orthoMCL	1	0.900	-	-		OOG6_100741
Panther	1	1.100	-	-	LDO	PTHR11135
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2945
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840