DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment morgue and PEX4

DIOPT Version :9

Sequence 1:	NP_608833.1	Gene:	morgue / 33648	FlyBaseID:	FBgn0027609	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_011649.1	Gene:	PEX4 / 853034	SGDID:	S000003365	Length:	183	Species:	Saccharomyces cerevisiae

Alignment Length:	147	Identity:	42/147 - (28%)
Similarity:	70/147 - (47%)	Gaps:	18/147 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 LRGEANLLNSYESEGISAIPLDRQN-NYWQATILGPPGSPYEGGKFFLFIYFPERYPMTPPTVRF 405
            |..:..:.|.|.....|..|:|..: :.|:|.|.||..:|||..:|.:.|..|..|||.||.:.|
Yeast    33 LASDDPIANPYRGIIESLNPIDETDLSKWEAIISGPSDTPYENHQFRILIEVPSSYPMNPPKISF 97

  Fly   406 L-TKILHPNV-SRHGDVGIDIFQQHNWSLALNVAKVLLSVQSLLTDPYTEVCMEPELGYI----- 463
            : ..|||.|| |..|::.::|.:...|:...::...:.:|..||.:|..:..::.::|.|
Yeast    98 MQNNILHCNVKSATGEICLNILKPEEWTPVWDLLHCVHAVWRLLREPVCDSPLDVDIGNIIRCGD 162

  Fly   464 ----------YEHERER 470
                      :..||||
Yeast   163 MSAYQGIVKYFLAERER 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
morgue	NP_608833.1	DUF3664	92..190	CDD:289191
		F-box-like	234..275	CDD:289689
		UQ_con	342..479	CDD:278603	42/147 (29%)
		COG5078	355..485	CDD:227410	39/134 (29%)
PEX4	NP_011649.1	COG5078	15..176	CDD:227410	38/142 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900