DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment morgue and UBE2D2

DIOPT Version :9

Sequence 1:	NP_608833.1	Gene:	morgue / 33648	FlyBaseID:	FBgn0027609	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_016865309.1	Gene:	UBE2D2 / 7322	HGNCID:	12475	Length:	173	Species:	Homo sapiens

Alignment Length:	210	Identity:	76/210 - (36%)
Similarity:	106/210 - (50%)	Gaps:	49/210 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   282 WP---LFD-SLADNPNWYRL-YGALMSSCFCRTCLIEMGGRGQD--AQEADPQLGDREPGNVMRN 339
            ||   ||. ::.|...|.|| :|..:       |..|:....:|  ||
Human     6 WPIDFLFPAAIGDWAEWTRLPFGNFL-------CAFELNDLARDPPAQ----------------- 46

  Fly   340 NFLRGEANLLNSYESEGISAIPLDRQNNYWQATILGPPGSPYEGGKFFLFIYFPERYPMTPPTVR 404
                             .||.|:.....:|||||:||..|||:||.|||.|:||..||..||.|.
Human    47 -----------------CSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVA 94

  Fly   405 FLTKILHPNVSRHGDVGIDIFQQHNWSLALNVAKVLLSVQSLLTDPYTEVCMEPELGYIYEHERE 469
            |.|:|.|||::.:|.:.:||.:. .||.||.::|||||:.|||.||..:..:.||:..||:.:||
Human    95 FTTRIYHPNINSNGSICLDILRS-QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRE 158

  Fly   470 RFEQLVRAWTWKYAM 484
            ::.::.|.||.||||
Human   159 KYNRIAREWTQKYAM 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
morgue	NP_608833.1	DUF3664	92..190	CDD:289191
		F-box-like	234..275	CDD:289689
		UQ_con	342..479	CDD:278603	56/136 (41%)
		COG5078	355..485	CDD:227410	62/130 (48%)
UBE2D2	XP_016865309.1	COG5078	35..173	CDD:227410	64/172 (37%)
UBE2D2	XP_016865309.1	UBCc	35..172	CDD:294101	63/171 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810