DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment morgue and ube2i

DIOPT Version :9

Sequence 1:	NP_608833.1	Gene:	morgue / 33648	FlyBaseID:	FBgn0027609	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001016408.1	Gene:	ube2i / 549162	XenbaseID:	XB-GENE-974017	Length:	158	Species:	Xenopus tropicalis

Alignment Length:	141	Identity:	45/141 - (31%)
Similarity:	69/141 - (48%)	Gaps:	19/141 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   344 GEANLLNSYESEGISAIPLDRQNNYWQATILGPPGSPYEGGKFFLFIYFPERYPMTPPTVRFLTK 408
            |..||:|                  |:..|.|..|:|:|||.|.|.:.|.:.||.:||..:|...
Frog    34 GTMNLMN------------------WECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPP 80

  Fly   409 ILHPNVSRHGDVGIDIFQQ-HNWSLALNVAKVLLSVQSLLTDPYTEVCMEPELGYIYEHERERFE 472
            :.||||...|.|.:.|.:: .:|..|:.:.::||.:|.||.:|..:...:.|...||...|..:|
Frog    81 LFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYE 145

  Fly   473 QLVRAWTWKYA 483
            :.|||...|:|
Frog   146 KRVRAQAKKFA 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
morgue	NP_608833.1	DUF3664	92..190	CDD:289191
		F-box-like	234..275	CDD:289689
		UQ_con	342..479	CDD:278603	43/135 (32%)
		COG5078	355..485	CDD:227410	41/130 (32%)
ube2i	NP_001016408.1	UQ_con	8..152	CDD:395127	43/135 (32%)
ube2i	NP_001016408.1	Interaction with sumo1. /evidence=ECO:0000250	13..18
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910