DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3652 and YIPF4

DIOPT Version :9

Sequence 1:	NP_608828.2	Gene:	CG3652 / 33643	FlyBaseID:	FBgn0031600	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_115688.1	Gene:	YIPF4 / 84272	HGNCID:	28145	Length:	244	Species:	Homo sapiens

Alignment Length:	234	Identity:	68/234 - (29%)
Similarity:	103/234 - (44%)	Gaps:	54/234 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EDVN---TSP----SLEGDMSIPGKRTTTATSASGV----------PEYNTLDEPIRETVLRDIR 56
            ||::   .||    :|.||. |.....||.....|.          ||.|   :|:.|.:..|::
Human    26 EDLSGSIASPDVKLNLGGDF-IKESTATTFLRQRGYGWLLEVEDDDPEDN---KPLLEELDIDLK 86

  Fly    57 AVGIKFYHVLYPKE----KSSLLRD-WDLWGPLVLCTFMATI-LQGSSTADSMSDNGPEFAQV-- 113
            .:..|...||.|..    ...::|| .|.||||.:..|.:.| |.|            :|..|
Human    87 DIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFSMISLYG------------QFRVVSW 139

  Fly   114 FVIVWI-GAAVVTLNSKLLGGNISFFQSVCVLGYCLTPVAISLIVCRVILLATQTRLLFFLRFVT 177
            .:.:|| |:..:.|.:::|||.:::.|.:.|:||.|.|    |||...:||...:     ...|:
Human   140 IITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLP----LIVIAPVLLVVGS-----FEVVS 195

  Fly   178 TTI---GFAWATYASFVFLGQSQPPHRKPLAVYPIFLFF 213
            |.|   |..||.|::...|...:...:|||.:|||||.:
Human   196 TLIKLFGVFWAAYSAASLLVGEEFKTKKPLLIYPIFLLY 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3652	NP_608828.2	Yip1	<31..221	CDD:304430	58/205 (28%)
YIPF4	NP_115688.1	Yip1	<74..237	CDD:389810	55/185 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5080
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810