Protein Alignment Tps1 and TPS3

DIOPT Version :10

• Sequence 1: NP_608827.1
• Gene: Tps1 / 33642
• FlyBaseID: FBgn0027560
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_013988.1
• Gene: TPS3 / 855303
• SGDID: S000004874
• Length: 1054
• Species: Saccharomyces cerevisiae
• Alignment Length: 669
• Identity: 179/669 - (26%)
• Similarity: 300/669 - (44%)
• Gaps: 104/669 - (15%)

  Fly    17 KASLIVVS----NRLPFVLIRDPKTDELERRASAGGLVTAVCPVVIKGSGLWVGWSGIHLKDPNE 77
            :|||:..|    ..||:.::...|.:...:.|    :..||....:|....|||..||
Yeast   298 RASLMRNSYELFKHLPWTIVDSDKGNGSLKNA----VNIAVAEKTVKEPVSWVGTMGI------- 351

  Fly    78 AIPESNPNDQTP-----TAGLKSEQVVS---VNIDSKIFDSYYNGCCNKIFWPLFH-SMPGRAN- 132
                  |.|:.|     ....|.||..|   |..|...|...|.....:|.||..| .:|...|
Yeast   352 ------PTDELPHEVCHKISKKLEQDFSSFPVVTDDITFKGAYKNYAKQILWPTLHYQIPDNPNS 410

  Fly   133 --FGGEHWHDYVTVNKHFAVRTIEALEKCLAKNQGSEKSPPIVWIHDYHLMLAANWVREHAEEKN 195
              |....|..|..||:.|:.|.:...           |....:|||||||||....|||     .
Yeast   411 KAFEDHSWDYYQKVNQKFSDRIVSVY-----------KPGDTIWIHDYHLMLVPQMVRE-----K 459

  Fly   196 LP-CRLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQDYCLNFVDCCQRNLGCRVDRN 259
            || .::.||||:.||..::||.|...:.||:|::|.:.|||..::|..:|:..|.|.|.  .|.:
Yeast   460 LPKAKIGFFLHVSFPSSEVFRCLANRERILEGIIGANFVGFQTKEYKRHFLQTCNRLLA--ADVS 522

  Fly   260 NLLVEHGGRTVRVRPLPIGIPYERFVNLATTAPKVLKTSKM--------QIILGVDRLDYTKGLV 316
            |..|::....|.|...||||.|....:..... .||:..::        ::|:..|:.|..:||.
Yeast   523 NDEVKYHCNIVSVMYAPIGIDYYHLTSQLRNG-SVLEWRQLIKERWRNKKLIVCRDQFDRIRGLQ 586

  Fly   317 HRLMAFEALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVDQLVGRINGRFTTANWA-PIRY 380
            .:::|:|..|::.|::.|||.|:||.:...:|.:..|::...||    |||...:..:.: |:.:
Yeast   587 KKMLAYERFLIENPEYIEKVVLIQICIGKSSDPEYERQIMVVVD----RINSLSSNISISQPVVF 647

  Fly   381 IYDYVSQDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQINEVPGVLVISPFAGAGEMMHE-AL 444
            ::..:...:..||..:|.|.||..||:||||...||:.... |....|::|.|.|:..::.| |:
Yeast   648 LHQDLDFAQYLALNCEADVFLVDALREGMNLTCHEFIVSSF-EKNAPLLLSEFTGSSSVLKEGAI 711

  Fly   445 LCNPYEVNEAAEVIHRALTMPEDERVLRMARLRRREAECDVSHWM-RCFLKAVGALEMDDVGTTI 508
            |.||:::|..|:.|.|:|.|..:|:..|..:|.:...|.|..:|: :||.....|.|.:...:|:
Yeast   712 LINPWDINHVAQSIKRSLEMSPEEKRRRWKKLFKSVIEHDSDNWITKCFEYINNAWESNQETSTV 776

  Fly   509 MQPVSVDDFDDYLLKYIGYNHKLALLLDYDGT-----LAPIAPHPDLATLSPEIKNVLYKLSNHS 568
            .. ::.:.|                ..||..:     :..|:..|....||     :|.:||:::
Yeast   777 FN-LAPEKF----------------CADYKASKKHLFIFKISEPPTSRMLS-----LLSELSSNN 819

  Fly   569 DVYVAVISGRNVDNVKKMV-GIEGITYAGNHGLEILHPDGSKFVHPMPMEYEKKVSDLLKALQDS 632
            .||  |:|....:..:.:. |:..|.....:|..: ..:||.:.....:::.|:|:   |...:.
Yeast   820 IVY--VLSSFTKNTFESLYNGVLNIGLIAENGAYV-RVNGSWYNIVEELDWMKEVA---KIFDEK 878

  Fly   633 VCR-DGAWVENKGALLTFH 650
            |.| .|::.:...:::.||
Yeast   879 VERLPGSYYKIADSMIRFH 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	PRK14501	20..766	CDD:184712	177/666 (27%)
TPS3	NP_013988.1	Glyco_transf_20	286..765	CDD:425972	149/507 (29%)
		Trehalose_PPase	785..1010	CDD:426737	26/124 (21%)