DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tps1 and TPS9

DIOPT Version :9

Sequence 1:	NP_608827.1	Gene:	Tps1 / 33642	FlyBaseID:	FBgn0027560	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_173799.1	Gene:	TPS9 / 838998	AraportID:	AT1G23870	Length:	867	Species:	Arabidopsis thaliana

Alignment Length:	888	Identity:	233/888 - (26%)
Similarity:	381/888 - (42%)	Gaps:	188/888 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 STKASLIVVSNRLPFVLIRDPKTDELERRASAGGLVTAVCPVVIKGSGLW-VGWSG----IHLKD 74
            |::...|:|:|.||....||.:|                        |.| ..|..    :.|:|
plant    56 SSRERKIIVANMLPLQAKRDTET------------------------GQWCFSWDEDSLLLQLRD 96

  Fly    75 ----PNEAIPESNPNDQTPTAGLKSEQVVS-----------VNIDSKIFDSYYNGCCNKIFWPLF 124
                ..|.:...:.|   ...|:..::.||           ..:..::.:.:|.|.|....||||
plant    97 GFSSDTEFVYIGSLN---ADIGISEQEEVSHKLLLDFNCVPTFLPKEMQEKFYLGFCKHHLWPLF 158

  Fly   125 HSM----PGRAN-FGGEHWHDYVTVNKHFAVRTIEALEKCLAKNQGSEKSPPIVWIHDYHLMLAA 184
            |.|    |...: |....|..||:.||.|:.|.:|.:          ......|||||||||:..
plant   159 HYMLPMFPDHGDRFDRRLWQAYVSANKIFSDRVMEVI----------NPEEDYVWIHDYHLMVLP 213

  Fly   185 NWVREHAEEKNLPCRLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQDYCLNFVDCCQ 249
            .::|:....    .:|.||||.|||..:|:|.||..|::|:|:|.|||:|||..||..:|:.||.
plant   214 TFLRKRFNR----IKLGFFLHSPFPSSEIYRTLPVRDDLLRGLLNCDLIGFHTFDYARHFLSCCS 274

  Fly   250 RNLGCRVD--RNNLLVEHGGRTVRVRPLPIGI---PYERFVNLATTAPKVLKTSKM----QIILG 305
            |.||...:  |.::.:::.||||.::.||:||   ..|..:||.:||.|:.:..:.    ::|||
plant   275 RMLGLDYESKRGHIGLDYFGRTVFIKILPVGIHMGRLESVLNLPSTAAKMKEIQEQFKGKKLILG 339

  Fly   306 VDRLDYTKGLVHRLMAFEALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVDQLVGRINGRF 370
            ||.:|..||:..:|:|.|.|...|...:.|:.|:||..|:|...|:..|.|:|......|||.|:
plant   340 VDDMDIFKGISLKLIAMERLFETYWHMRGKLVLIQIVNPARATGKDVEEAKKETYSTAKRINERY 404

  Fly   371 TTANWAPIRYIYDYVSQDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQINEVPG--------- 426
            .:|.:.|:..|...|.:.|..|.|..|..|||..:|||||||..:::.|: ...||
plant   405 GSAGYQPVILIDRLVPRYEKTAYYAMADCCLVNAVRDGMNLVPYKYIICR-QGTPGMDKAMGISH 468

  Fly   427 ------VLVISPFAGAGEMMHEALLCNPYEVNEAAEVIHRALTMPEDERVLRMARLRRREAECDV 485
                  :||:|.|.|....:..|:..||::|:..||.::.||||.|.|:.||..:.....:..||
plant   469 DSARTSMLVVSEFIGCSPSLSGAIRVNPWDVDAVAEAVNLALTMGETEKRLRHEKHYHYVSTHDV 533

  Fly   486 SHWMRCFLK---------------AVG------ALEMDDVGTTIMQPVSVDDFDDYLLKYIGYNH 529
            .:|.:.|::               .:|      .|.:    :...:.:|:    |:::.......
plant   534 GYWAKSFMQDLERACREHYNKRCWGIGFGLSFRVLSL----SPSFRKLSI----DHIVSTYRNTQ 590

  Fly   530 KLALLLDYDGTLAPIAPHPDLATLSPEIKNVLYKLSNHSDVYVAVISGRNVDNVKKMVG-IEGIT 593
            :.|:.|||||||.|  ....:.|.:.|:.:||..|.......|.|:|||..:::...:. .|.:.
plant   591 RRAIFLDYDGTLVP--ESSIIKTPNAEVLSVLKSLCGDPKNTVFVVSGRGWESLSDWLSPCENLG 653

  Fly   594 YAGNHGLEILHPDGSKF---VHPMPMEYEKKVSDLLKALQDSVCRDGAWVENKGALLTFHY---- 651
            .|..||..|......::   ......|::..|..::::..|:.  ||:.:|.|.:.|.:|:
plant   654 IAAEHGYFIRWSSKKEWETCYSSAEAEWKTMVEPVMRSYMDAT--DGSTIEYKESALVWHHQDAD 716

  Fly   652 --------RETPNHLRGAMVDKARSLIEKYGFKATEAHCALEARPPVQWNKGRASIYILRTSFGV 708
                    :|..:||...:.::  .::.|.|....|.       .|...:||.|...::. ....
plant   717 PDFGACQAKELLDHLESVLANE--PVVVKRGQHIVEV-------KPQGVSKGLAVEKVIH-QMVE 771

  Fly   709 DWNERIKIIYVGDDLTDEDAMVALKGMARTFRVTSSDIVKTAADHRLPSTDSVYTLLKWVERHFM 773
            |.|....::.:|||.:|||..              ..|:.|..:..||....::...       :
plant   772 DGNPPDMVMCIGDDRSDEDMF--------------ESILSTVTNPDLPMPPEIFACT-------V 815

  Fly   774 GRKARANSLTYRPTK--------GDGVQMQMSLEVAASANNLE 808
            |||         |:|        .|.:::...|..|.|::..|
plant   816 GRK---------PSKAKYFLDDVSDVLKLLGGLAAATSSSKPE 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	GT1_TPS	19..495	CDD:99963	163/539 (30%)
		PRK14501	20..766	CDD:184712	222/831 (27%)
		HAD_like	530..770	CDD:304363	55/255 (22%)
TPS9	NP_173799.1	PLN02205	1..849	CDD:177855	232/886 (26%)
		GT1_TPS	62..545	CDD:99963	163/524 (31%)
		Trehalose_PPase	595..830	CDD:280512	59/278 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	281	1.000	Domainoid score	I392
eggNOG	1	0.900	-	-		E1_COG1877
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	298	1.000	Inparanoid score	I792
OMA	1	1.010	-	-		QHG54965
OrthoDB	1	1.010	-	-		D772297at2759
OrthoFinder	1	1.000	-	-		FOG0000556
OrthoInspector	1	1.000	-	-		otm2519
orthoMCL	1	0.900	-	-		OOG6_100616
Panther	1	1.100	-	-	O	PTHR10788
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X473
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840