DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tps1 and TPS3

DIOPT Version :9

Sequence 1:	NP_608827.1	Gene:	Tps1 / 33642	FlyBaseID:	FBgn0027560	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_173143.4	Gene:	TPS3 / 838270	AraportID:	AT1G17000	Length:	783	Species:	Arabidopsis thaliana

Alignment Length:	860	Identity:	248/860 - (28%)
Similarity:	383/860 - (44%)	Gaps:	195/860 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GEPSTKASLIVVSNRLPFVLIRDPKTDELERRASAGGLVTAVCPVVIKGSGLWVGWS-------G 69
            ||..|   |:||:||||               |||            |.:|.. .||       .
plant     8 GERQT---LLVVANRLP---------------ASA------------KRTGEH-SWSLEMSPGGK 41

  Fly    70 IHLKDPNEAIPESNPNDQTPTAGLKSEQVVSVNIDSKIFDSYYNGCCNKIFWPLFHSMPGRANFG 134
            .:|....:|:.:|          |...:.:.|.: :::||.||||..|.|.||:.|.|    ...
plant    42 FNLLVEKDAVSKS----------LAEMKCIPVFL-NEVFDQYYNGYSNGILWPILHHM----GLP 91

  Fly   135 GEHWHD-----------YVTVNKHFAVRTIEALEKCLAKNQGSEKSPPIVWIHDYHLMLAANWVR 188
            .|:.||           |...|:.|    ::.:::       :.|...|||..|||||....:::
plant    92 QEYDHDTIKTFETQYDAYKKANRMF----LDVIKE-------NYKDGDIVWCQDYHLMFLPQYLK 145

  Fly   189 EHAEEKNLPCRLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQDYCLNFVDCCQRNLG 253
            |:    |...::.:|||.|||..:|::.||...|:|:.:|..||:.||..|:..:||:.|.|.||
plant   146 EY----NNKIKVGWFLHSPFPSSEIYKTLPSRSELLRSVLAADLISFHTYDFARHFVNTCTRILG 206

  Fly   254 CRVDRNNLLVEHGGRTVRVRPLPIGIPYERFVNLATTAPKVL--------KTSKMQIILGVDRLD 310
              |:..:..|.:.||..||..||:||...||:. ....|:|:        :.|..::||||||||
plant   207 --VEGTHEGVVYQGRVTRVVVLPMGIYPNRFIK-TCKLPEVIQQMNELKDRFSGKKVILGVDRLD 268

  Fly   311 YTKGLVHRLMAFEALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVDQLVGRINGRFTTANW 375
            ..||:..:.:.||..|.:.|..::|:.|:||:||:|.:|.||::||.:|.:|||||||||.:.:.
plant   269 MIKGIPQKYLGFEKFLDENPNWRDKIVLVQIAVPTRNEVPEYQKLKNQVHRLVGRINGRFGSVSS 333

  Fly   376 APIRYIYDYVSQDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQINEVPGVLVISPFAGAGEMM 440
            .||.::...|..:.|.|||..:.|.|||.||||:|||:.|||||| ....|||::|.|||||:.:
plant   334 LPIHHMDCSVDSNYLCALYAISDVMLVTSLRDGLNLVSHEFVACQ-EAKRGVLILSEFAGAGQSL 397

  Fly   441 HE-ALLCNPYEVNEAAEVIHRALTMPEDERVLR----MARLRRREAECDVSHWMRCFLKAVGALE 500
            .. |||.||:.|.|.:..|.:||.||.:||..|    ...::...||    .|...||.     |
plant   398 GAGALLVNPWNVTEVSSAIKKALNMPYEERETRHRVNFKYVKTHSAE----KWGFDFLS-----E 453

  Fly   501 MDDVGTTIMQPVSVDDFD----------------DYLLKYIGYNHKLALLLDYDGTLA----PIA 545
            ::|.            ||                |.:.:|...|::| ::|.:.||:.    .::
plant   454 LNDA------------FDESELQIRKIPHELPQQDVIQRYSLSNNRL-IILGFYGTITEPRNSLS 505

  Fly   546 PHPDLATLSPEIKNVLYKLSNHSDVYVAVI--SGRNVDNVKKMVGIEGITYAGNHGLEILHPDGS 608
            ...|| .|:||:|..|..|.|.....|.|:  ||:|:  :.|..|...|..|..:|:.:.|.. .
plant   506 KEMDL-XLNPELKETLKALCNDPKTTVVVLSRSGKNI--LDKNFGEYKIWLAAENGMFLKHTT-E 566

  Fly   609 KFVHPMPMEYEKKVSDLLKALQDSVCRDGAWVENKGALLTFHYRETPNHLRGAMVDKARSLIEKY 673
            ::|..||......                 ||:....:..:....||   |........||:..|
plant   567 EWVTNMPQNMNLD-----------------WVDGLKNVFKYFTDRTP---RSFFEASKTSLVWNY 611

  Fly   674 GFKATEAHCALEARPPVQ--WNK--GRASIYILRTSFGVDWN-----ERIKIIYVGDDLTDEDAM 729
            .:...|...| :||..:|  |..  ..||..::|..:.|:.:     :..:|.::..::..:.||
plant   612 EYADVEFGRA-QARDLLQYLWAGPISNASAEVVRGKYSVEVHAIGVTKEPEIGHILGEIVHKKAM 675

  Fly   730 VALKGMARTFRVTSSDIVKTAADHRLPSTDSVYTLLKWVERHFMGRKARANSLTYRPTKGDGVQM 794
                       .|..|.| ..:.:.|...:.:||        |...:..:..|::. |:......
plant   676 -----------TTPIDYV-FCSGYFLEKDEDIYT--------FFESEILSPKLSHE-TRSKSSSS 719

  Fly   795 QMSLEVAASANNLEV 809
            ..|||...|.|.|::
plant   720 NHSLEKKVSLNVLDL 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	GT1_TPS	19..495	CDD:99963	175/506 (35%)
		PRK14501	20..766	CDD:184712	236/807 (29%)
		HAD_like	530..770	CDD:304363	54/254 (21%)
TPS3	NP_173143.4	PLN03063	1..783	CDD:215555	248/860 (29%)
		GT1_TPS	13..455	CDD:99963	176/512 (34%)
		HAD_like	490..702	CDD:304363	54/256 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	281	1.000	Domainoid score	I392
eggNOG	1	0.900	-	-		E1_COG1877
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	298	1.000	Inparanoid score	I792
OMA	1	1.010	-	-		QHG54965
OrthoDB	1	1.010	-	-		D772297at2759
OrthoFinder	1	1.000	-	-		FOG0000556
OrthoInspector	1	1.000	-	-		otm2519
orthoMCL	1	0.900	-	-		OOG6_100616
Panther	1	1.100	-	-	O	PTHR10788
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X473
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840