DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tps1 and TPS4

DIOPT Version :9

Sequence 1:	NP_608827.1	Gene:	Tps1 / 33642	FlyBaseID:	FBgn0027560	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_194485.1	Gene:	TPS4 / 828864	AraportID:	AT4G27550	Length:	795	Species:	Arabidopsis thaliana

Alignment Length:	822	Identity:	234/822 - (28%)
Similarity:	377/822 - (45%)	Gaps:	136/822 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LIVVSNRLPFVLIRDPKTDELERRASAGGLVTAVCPVVIKGSGL------WVGWSGIHLKDPNEA 78
            |:|||..|| |..:....:......|.||||:|:.       ||      |:||.|:   |.::|
plant     6 LLVVSMSLP-VTAKRTGEESWSFTMSPGGLVSALL-------GLKEFETKWIGWPGV---DVHDA 59

  Fly    79 IPESNPNDQTPTAGLKSEQVVSVNIDSKIFDSYYNGCCNKIFWPLFHSM---PGRANFGGEHWHD 140
            |     ..:|.:..|..:..:.|.:: ::.|.||||.||.|.||:||.:   |       |:.:|
plant    60 I-----GKKTLSITLAEKGCIPVFLE-EVCDQYYNGYCNNILWPIFHYLGTPP-------EYRND 111

  Fly   141 -YVTVNKHFAVRTIEALEKC------LAKNQGSEKSPPIVWIHDYHLMLAANWVREHAEEKNLPC 198
             .:|....:     ||.:|.      :.|....|..  :||.||||:||...:::|:    |...
plant   112 ATITYQSQY-----EAYKKANQIFFDVVKEHYEEGD--VVWCHDYHVMLLPQYLKEY----NSKM 165

  Fly   199 RLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQDYCLNFVDCCQRNLGCRVDRNNLLV 263
            ::.:|||.|||..::::.||...::|:.:|..||||||..|:..:|::.|...||.......::.
plant   166 KVGWFLHTPFPSSEMYKTLPSRSDLLRSVLTADLVGFHTYDFARHFLNACMCILGVEATSEGIVD 230

  Fly   264 EHGGRTVRVRPLPIGIPYERFVNLATTAPKVLKTSKM-------QIILGVDRLDYTKGLVHRLMA 321
            :  |:..||...||||..|||:|.:..:..|....|.       ::||||||||..||:..:..|
plant   231 Q--GKVTRVAVFPIGIEPERFINTSELSEVVQYMKKFKNDFGGRKLILGVDRLDTIKGIPQKYQA 293

  Fly   322 FEALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVDQLVGRINGRFTTANWAPIRYIYDYVS 386
            ||..|.:..:.:.||.||||:||:|..:.||:::|::....||||||||.:.:..||.::...:.
plant   294 FEKFLEENAEWRGKVMLLQIAVPTRNGIGEYQKIKDQCHYHVGRINGRFGSISSVPIIHLDCSID 358

  Fly   387 QDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQINEVPGVLVISPFAGAGEMMHE-ALLCNPYE 450
            .::|.|||....|.|||.||||||||:.||:|||..| .|||::|.|||||:.:.. |:|.||:.
plant   359 FNQLCALYAITDVLLVTSLRDGMNLVSSEFIACQKAE-KGVLILSEFAGAGQSLGAGAILVNPWN 422

  Fly   451 VNEAAEVIHRALTMPEDERVLRMARLRRREAEC-DVSHWMRCFL----------KAVGALEMDDV 504
            :.|.:..|..||.|..:|:. |..::..:..:. ....|...|:          |.:......::
plant   423 IKEVSSAIGEALNMSHEEKE-RKHKINFQYVKTHSTQQWADDFMKLTLTNILCSKLIEITTSAEL 486

  Fly   505 GTTIMQPVSVDDFDDYLLKYIGYNHKLALLLDYDGTLAPIAPHPDL------ATLSPEIKNVLYK 563
            |..:...:.:.: .|.:.:|...|::| |:|.:.|||.....:.:.      ..|.|::|..|.:
plant   487 GAGLAATLELPE-HDVIQQYSKSNNRL-LILGFYGTLTQPMKNQERRGDGMNLELHPQLKERLKE 549

  Fly   564 LSNHSDVYVAVISGRNVDNVKKMVGIEGITYAGNHGLEILHPDG---SKFVHPMPMEYEKKVSDL 625
            |.:.....|.|:|......:.|..|...:..|..:|:.:.|..|   ::....|.:|:...|..:
plant   550 LCSDPKTTVVVLSRSEKCILDKNFGEYNMWLAAENGMFLRHTSGEWVTRIPEHMNLEWIDGVKHV 614

  Fly   626 LKALQDSVCRDGAWVENKGALLTFHY------------RETPNHL-----RGAMVDKAR--SLIE 671
            .|...:..  .|:::|...|.|.::|            |:...||     ..|.||..|  ..:|
plant   615 FKYFTERT--PGSYLETSEASLVWNYENADAEFGRAQARDMLQHLWAGPISNASVDVVRGGQSVE 677

  Fly   672 KYGFKATEAHCALEARPPVQWNKGRAS--IYIL------------RTSFGVDWNERIK-IIYVGD 721
            .:....|:..........:..||..|:  .|:|            .|.|..:..::.| :...|.
plant   678 VHAVGVTKGSAMERILGEIVHNKSMATPIDYVLCIGCFLGKDEDVYTFFEPELTKKAKSLSSSGS 742

  Fly   722 DLTDE--DAMVALKG-------------MARTFRVTSSDIVK 748
            |...:  ..:|.|||             .||.|..:|.|:||
plant   743 DSPKKVSSTIVDLKGENYFSVAIGQTHTKARYFLDSSDDVVK 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	GT1_TPS	19..495	CDD:99963	170/509 (33%)
		PRK14501	20..766	CDD:184712	234/822 (28%)
		HAD_like	530..770	CDD:304363	59/277 (21%)
TPS4	NP_194485.1	PLN03063	1..795	CDD:215555	234/822 (28%)
		GT1_TPS	5..466	CDD:99963	170/498 (34%)
		Trehalose_PPase	514..780	CDD:280512	53/267 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	281	1.000	Domainoid score	I392
eggNOG	1	0.900	-	-		E1_COG1877
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	298	1.000	Inparanoid score	I792
OMA	1	1.010	-	-		QHG54965
OrthoDB	1	1.010	-	-		D772297at2759
OrthoFinder	1	1.000	-	-		FOG0000556
OrthoInspector	1	1.000	-	-		otm2519
orthoMCL	1	0.900	-	-		OOG6_100616
Panther	1	1.100	-	-	O	PTHR10788
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X473
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840