DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tps1 and TPS5

DIOPT Version :9

Sequence 1:	NP_608827.1	Gene:	Tps1 / 33642	FlyBaseID:	FBgn0027560	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_001329809.1	Gene:	TPS5 / 827498	AraportID:	AT4G17770	Length:	862	Species:	Arabidopsis thaliana

Alignment Length:	852	Identity:	238/852 - (27%)
Similarity:	378/852 - (44%)	Gaps:	157/852 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IVTNAGEPSTKASLIVVSNRLPFVLIRDPKTDELERRASAGGLVTAVCPVVIKGSGLWVGWSG-- 69
            :.::|....|:..:|:|.|:||.          ...|.|||.|.              ..|..
plant    49 VCSDAPSSVTQDRIIIVGNQLPI----------KSHRNSAGKLS--------------FSWDNDS 89

  Fly    70 --IHLKDP-------------NEAIPESNPNDQTPTAGLKSEQVVSVNIDSKIFDSYYNGCCNKI 119
              :.|||.             .|.| ::...|......|::.:.|...|..::|..||:|.|.:.
plant    90 LLLQLKDGMREDMEVVYIGCLKEQI-DTVEQDDVSQRLLENFKCVPAYIPPELFTKYYHGFCKQH 153

  Fly   120 FWPLFHSM-PGRANFGGEH----WHDYVTVNKHFAVRTIEALEKCLAKNQGSEKSP--PIVWIHD 177
            .|||||.| |...:.||..    |..|::|||.||.:.:|.:            ||  ..||:||
plant   154 LWPLFHYMLPLTPDLGGRFDRSLWQAYLSVNKIFADKVMEVI------------SPDDDFVWVHD 206

  Fly   178 YHLMLAANWVREHAEEKNLPCRLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQDYCL 242
            ||||:...::|:....    .:|.||||.|||..:|:|.||..:|:|:.:|..||:|||..||..
plant   207 YHLMVLPTFLRKRFNR----VKLGFFLHSPFPSSEIYRTLPVRNELLRALLNADLIGFHTFDYAR 267

  Fly   243 NFVDCCQRNLGC--RVDRNNLLVEHGGRTVRVRPLPIGI---PYERFVNLATTAPKVLKTS---- 298
            :|:.||.|.||.  :..|..:.:|:.||||.::.||:||   ..:..:||..|..||.:..
plant   268 HFLSCCSRMLGLSYQSKRGTIGLEYYGRTVSIKILPVGIHISQLQSILNLPETQTKVAELRDQFL 332

  Fly   299 KMQIILGVDRLDYTKGLVHRLMAFEALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVDQLV 363
            ..:::||||.:|..||:..:|:|.|.||.::|:.:.:|.|:||:.|:|...|:.:|::.|.:..|
plant   333 DQKVLLGVDDMDIFKGISLKLLAMEQLLTQHPEKRGRVVLVQIANPARGRGKDVQEVQSETEATV 397

  Fly   364 GRINGRFTTANWAPIRYIYDYVSQDELAALYRDAAVCLVTPLRDGMNLVAKEFVAC-----QINE 423
            .|||..|....:.|:..|...:...|..|.|..|..||||.:||||||:..|::.|     ::||
plant   398 KRINEMFGRPGYQPVVLIDTPLQFFERIAYYVIAECCLVTAVRDGMNLIPYEYIICRQGNPKLNE 462

  Fly   424 VPG---------VLVISPFAGAGEMMHEALLCNPYEVNEAAEVIHRALTMPEDERVLRMARLRRR 479
            ..|         :||:|.|.|....:..|:..||:.::...|.:..||.:.|.|:.:|..:..:.
plant   463 TIGLDPSAAKKSMLVVSEFIGCSPSLSGAIRVNPWNIDAVTEAMDYALIVSEAEKQMRHEKHHKY 527

  Fly   480 EAECDVSHWMRCFLKAVGALEMDDVGTTI--------MQPVSVD-DFDDYLLKYIGYNHK----L 531
            .:..||::|.|.|::.:.....|.|....        .:.|::| .|....:::|...:|    .
plant   528 VSTHDVAYWARSFIQDLERACGDHVRKRCWGIGFGLGFRVVALDPSFKKLSIEHIVSAYKRTKNR 592

  Fly   532 ALLLDYDGTLAPIAPHPDLATLSPEIKNVLYKLSNHSDVYVAVISGRNVDNVKK-MVGIEGITYA 595
            |:|||||||:  :.|.....|.:.|...:|..||:.....|.::||::...:.: ....:.:...
plant   593 AILLDYDGTM--VQPGSIRTTPTRETIEILNNLSSDPKNIVYLVSGKDRRTLTEWFSSCDDLGLG 655

  Fly   596 GNHGLEILHPDGSKFVHPMPMEYEKKVSDL-LKALQDSVCR------DGAWVENKGALLTFHY-- 651
            ..||..|...||:.:      |....||.. .|.:.:.|.|      ||:.:|.|...|.::|
plant   656 AEHGYFIRPNDGTDW------ETSSLVSGFEWKQIAEPVMRLYTETTDGSTIETKETALVWNYQF 714

  Fly   652 ----------RETPNHLRGAMVDKARSLIEKYGFKATEAHCALEARPPVQWNKGRASIYILRTSF 706
                      :|...||...:.:...|:  |.|.:..|.       .|...|||..:..:|.|
plant   715 ADPDFGSCQAKELMEHLESVLTNDPVSV--KTGQQLVEV-------KPQGVNKGLVAERLLTT-- 768

  Fly   707 GVDWNERIK----IIYVGDDLTDEDAM---------VALKGMARTFRVTSSDIVKTAADHRLPST 758
               ..|:.|    |:.||||.:|||..         .||..:|..|..|... ..:.|.:.|..|
plant   769 ---MQEKGKLLDFILCVGDDRSDEDMFEVIMSAKDGPALSPVAEIFACTVGQ-KPSKAKYYLDDT 829

  Fly   759 DSVYTLL 765
            ..:..:|
plant   830 AEIIRML 836

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	GT1_TPS	19..495	CDD:99963	163/522 (31%)
		PRK14501	20..766	CDD:184712	236/839 (28%)
		HAD_like	530..770	CDD:304363	67/273 (25%)
TPS5	NP_001329809.1	PLN02205	1..850	CDD:177855	238/852 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	281	1.000	Domainoid score	I392
eggNOG	1	0.900	-	-		E1_COG1877
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	298	1.000	Inparanoid score	I792
OMA	1	1.010	-	-		QHG54965
OrthoDB	1	1.010	-	-		D772297at2759
OrthoFinder	1	1.000	-	-		FOG0000556
OrthoInspector	1	1.000	-	-		otm2519
orthoMCL	1	0.900	-	-		OOG6_100616
Panther	1	1.100	-	-	O	PTHR10788
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X473
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840