DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tps1 and TPS11

DIOPT Version :9

Sequence 1:	NP_608827.1	Gene:	Tps1 / 33642	FlyBaseID:	FBgn0027560	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_179460.1	Gene:	TPS11 / 816385	AraportID:	AT2G18700	Length:	862	Species:	Arabidopsis thaliana

Alignment Length:	889	Identity:	226/889 - (25%)
Similarity:	380/889 - (42%)	Gaps:	183/889 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 NAGEPSTKASLIVVSNRLPFVLIRDPKTDELERRASAGGLVTAVCPVVIKGSGLWVGW------S 68
            |.|...||...|||||:||....||..:::                           |      .
plant    42 NGGAWVTKPKRIVVSNQLPLRAHRDISSNK---------------------------WCFEFDND 79

  Fly    69 GIHLKDPNEAIPESN------------PNDQTPTAG--LKSEQVVSVNIDSKIFDSYYNGCCNKI 119
            .::|:..:...||:.            |::|...:.  |:..|.|...:.|.:.:.||:|.|...
plant    80 SLYLQLKDGFPPETEVVYVGSLNADVLPSEQEDVSQFLLEKFQCVPTFLPSDLLNKYYHGFCKHY 144

  Fly   120 FWPLFH----------SMPGRANFGGEHWHDYVTVNKHFAVRTIEALEKCLAKNQGSEKSPPIVW 174
            .||:||          |:..|:|     |..|.||||.||.:..|.|          ......||
plant   145 LWPIFHYLLPMTQAQGSLFDRSN-----WRAYTTVNKIFADKIFEVL----------NPDDDYVW 194

  Fly   175 IHDYHLMLAANWVREHAEEKNLPCRLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQD 239
            |||||||:...::|.....    .:|..|||.|||..:|:|.||..||||:|.|.|||||||..|
plant   195 IHDYHLMILPTFLRNRFHR----IKLGIFLHSPFPSSEIYRTLPVRDEILKGFLNCDLVGFHTFD 255

  Fly   240 YCLNFVDCCQRNLGCRVD--RNNLLVEHGGRTVRVRPLPIGIPYERFVNLATTAPKVLKTSKMQ- 301
            |..:|:.||.|.||...:  |..:.:|:.||||.::.||:||...:..::..:.....|..:::
plant   256 YARHFLSCCSRMLGLDYESKRGYIGLEYFGRTVSIKILPVGIHMGQIESIKASEKTAEKVKRLRE 320

  Fly   302 ------IILGVDRLDYTKGLVHRLMAFEALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVD 360
                  ::||||.||..||:..:..|...||.:..:.:.||.|:||:.|:|:..|:.::::::::
plant   321 RFKGNIVMLGVDDLDMFKGISLKFWAMGQLLEQNEELRGKVVLVQITNPARSSGKDVQDVEKQIN 385

  Fly   361 QLVGRINGRF-TTANWAPIRYIYDYVSQDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQ---- 420
            .:...||.:| ....:.||.:|...||..:..|.|..:...:|..:|||||||..::...:
plant   386 LIADEINSKFGRPGGYKPIVFINGPVSTLDKVAYYAISECVVVNAVRDGMNLVPYKYTVTRQGSP 450

  Fly   421 -INEVPG---------VLVISPFAGAGEMMHEALLCNPYEVNEAAEVIHRALTMPEDERVLRMAR 475
             ::...|         |:::|.|.|....:..|:..||:.::.....:..|:||.:.|:.||..:
plant   451 ALDAALGFGEDDVRKSVIIVSEFIGCSPSLSGAIRVNPWNIDAVTNAMSSAMTMSDKEKNLRHQK 515

  Fly   476 LRRREAECDVSHWMR---------C---------------FLKAVGALEMDD---VGTTIMQPVS 513
            ..:..:..:|::|.|         |               |.|.| ||:.:.   .|.||:.
plant   516 HHKYISSHNVAYWARSYDQDLQRACKDHYNKRFWGVGFGLFFKVV-ALDPNFRRLCGETIVP--- 576

  Fly   514 VDDFDDYLLKYIGYNHKLALLLDYDGTLAPIAPHPDLATL----SPEIKNVLYKLSNHSDVYVAV 574
                     .|...:.:| :|||||||:.      |..||    |.::.::|.:|.:.....|.:
plant   577 ---------AYRRSSSRL-ILLDYDGTMM------DQDTLDKRPSDDLISLLNRLCDDPSNLVFI 625

  Fly   575 ISGRNVDNVKKMVGIEGITYAGNHGLEILHPDGSKFVHPMPMEYEKKVSDL-LKALQDSV----- 633
            :|||..|.:.|.     .....|.|:...|...:::....|.|..:..:|| .|.:...|
plant   626 VSGRGKDPLSKW-----FDSCPNLGISAEHGYFTRWNSNSPWETSELPADLSWKKIAKPVMNHYM 685

  Fly   634 -CRDGAWVENKGALLTFHYRETPNHLRGA-----MVDKARSLIEKYGFKATEAHCALEARPPVQW 692
             ..||:::|.|.:.:.:|::|. :|..|:     ::|...|::.............:|.:|. ..
plant   686 EATDGSFIEEKESAMVWHHQEA-DHSFGSWQAKELLDHLESVLTNEPVVVKRGQHIVEVKPQ-GV 748

  Fly   693 NKGRASIYILRTSFGVDWNERIKIIYVGDDLTDEDAM--------VALKGMARTFRVTSSDIVKT 749
            :||:...:::.|...........::.:|||.:|||..        |:..|:...|..|... ..:
plant   749 SKGKVVEHLIATMRNTKGKRPDFLLCIGDDRSDEDMFDSIVKHQDVSSIGLEEVFACTVGQ-KPS 812

  Fly   750 AADHRLPSTDSVYTLLKWVERHFMGRK----ARANSLTYRPTKG 789
            .|.:.|..|.||..:|:|:.....|.|    .:.:..|::...|
plant   813 KAKYYLDDTPSVIKMLEWLASASDGSKHEQQKKQSKFTFQQPMG 856

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	GT1_TPS	19..495	CDD:99963	149/553 (27%)
		PRK14501	20..766	CDD:184712	216/850 (25%)
		HAD_like	530..770	CDD:304363	61/263 (23%)
TPS11	NP_179460.1	PLN02205	1..836	CDD:177855	222/867 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1877
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	298	1.000	Inparanoid score	I792
OMA	1	1.010	-	-		QHG54965
OrthoDB	1	1.010	-	-		D772297at2759
OrthoFinder	1	1.000	-	-		FOG0000556
OrthoInspector	1	1.000	-	-		otm2519
orthoMCL	1	0.900	-	-		OOG6_100616
Panther	1	1.100	-	-	O	PTHR10788
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X473
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.840