Protein Alignment Tps1 and tps-2

DIOPT Version :9

• Sequence 1: NP_608827.1
• Gene: Tps1 / 33642
• FlyBaseID: FBgn0027560
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_497035.3
• Gene: tps-2 / 3565050
• WormBaseID: WBGene00006603
• Length: 1229
• Species: Caenorhabditis elegans
• Alignment Length: 925
• Identity: 221/925 - (23%)
• Similarity: 359/925 - (38%)
• Gaps: 221/925 - (23%)

  Fly    20 LIVVSNRLPFVLIRDPKTDELERRASAGGLVTAVCPVVIKG-SGLWVGWSGIHLKDPNE------ 77
            :|.|||..|..|.|: ||.:.|.:..:||||..|.||:.|. ..||:...|:::.|..:
 Worm   239 VINVSNAPPVSLKRE-KTGDWEIKQGSGGLVACVDPVMSKDHENLWLANLGMNINDKKQKRPGSV 302

  Fly    78 -AIPESNPNDQTPTAGL-----------------------------KSEQVVS------------ 100
             :||||.|:  |.|.||                             |:.:.:|
 Worm   303 ASIPESFPS--TNTLGLPLIKQTIAEVFFHVLADDDMDAPKNEKQKKAREEMSLLGVLNNYNRGN 365

  Fly   101 -----VNIDSKIFDSYYNGCCNKIFWPLFHSMPGR--ANFGGE-----HWHDYVTVNKHFAVRTI 153
                 |.:....::.||.|..|.:.||..|::|..  :.:..|     ||..||.||..||:..:
 Worm   366 YKLNPVVVQEDDYNVYYGGISNGLLWPALHNLPEYIVSEYDDEKILRAHWCAYVRVNYQFAIDAV 430

  Fly   154 EALEKCLAKNQGSEKSPPIVWIHDYHLMLAANWVR---EHAEEKNLPCRLAFFLHIPF-PPWDIF 214
            .           :.:....:|||||||||....::   :|.|       :.||||||| ||.:.|
 Worm   431 R-----------NSRPQDFIWIHDYHLMLVGMIMQSLDQHLE-------VGFFLHIPFQPPGEFF 477

  Fly   215 -RLLPWSDEILQGMLGCDLVGFHIQDYCLNFVDCCQRNLG-CRVDRNNLL----VEHGGRTVRVR 273
             :.......:|:|:|....|||........:::..|...| .::..:|.:    :.:.|.|..:.
 Worm   478 SKYSTVGFAVLRGLLRFTKVGFQTHRDRTKYIELVQHYFGTAKIVYDNKMDIYSITNEGWTCSLG 542

  Fly   274 PLPIGI---PYERFVNLATTAPKVLKTSKMQIILG------------VDRLDYTKGLVHRLMAFE 323
            ..|:.|   .:.:||:|..|..  ||....:.::|            |:|.|||||::.:|.|::
 Worm   543 VFPVSIKNDDFLKFVDLPETIK--LKNDLRKRVMGDTPAPDGRFFFSVERFDYTKGIMEKLQAYK 605

  Fly   324 ALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVDQLVGRINGRFTTAN---WAPIRYIYDYV 385
            ....::|....|..|.||:|.:|..|..||..::|...|..:||..|...|   |.|:.:..|.:
 Worm   606 RYFERHPDRIGKDVLFQIAVTNRRSVDTYRVYQDECIDLADKINEIFKDPNNPTWKPLVFQTDGL 670

  Fly   386 SQDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQINEVPGVLVISPFAGAGEMMHEA------- 443
            .:.||.|.|....:.:|||.:|||||||||.:.|  |...| ||:|..||:......|
 Worm   671 PRSELVAAYLAMDIGVVTPKKDGMNLVAKEMLVC--NPKAG-LVLSTGAGSEIQFTTAGLYSDKE 732

  Fly   444 ----LLCNPYEVNEAAEVIHRALTMPEDERVLRMARLRRREAECDVSHWMRCFLKAVGALEMDDV 504
                .:.|.::.:...:..:.|...|||.|.....||.......|:..|...||......|
 Worm   733 KNYHRISNVFDPDSYCDAFYSAALEPEDVRAEHGKRLHEFIMANDIERWSCAFLDPSWTHE---- 793

  Fly   505 GTTIMQPVSVDDFDDY-----------------LLKYIGYNHKLALLLD----------YDGT-L 541
               :::|..|:..||:                 :||.|......|:.|.          ..|| .
 Worm   794 ---VIRPTQVETLDDFFSLMMKTRNVRRQIVGRVLKGIPIRSHFAISLRNAKESLEQICKPGTHT 855

  Fly   542 APIAPHPDLATLSP-EIKNVLYKLSNHSDVYVAVISGRNVDNVKKMVGIEGITYAGNHGLEILHP 605
            |.....||...::. ||.|.|.:...... ::..:...:.|||::.|
 Worm   856 AEFKSGPDSKEVAHFEIDNELQEFERDLS-FIDYVQSDDADNVEQFV------------------ 901

  Fly   606 DGSKFVHPMPME-YEKKVSDLLKALQDSVCRDGAWVENKGALLTFHYRETPNHLRGAMVDKARSL 669
            |.....||:.:| |:|:|.:.::.|..:......:.:..|.|.::.. ..|:.::.|.    ..:
 Worm   902 DTLISSHPISVETYKKEVENAVELLYSADHFHYFFTDRDGTLKSYSC-SYPSSIQPAY----SGV 961

  Fly   670 IEKYGFKATEAHCALEARPPVQWNKGRASI-------YILRTSFGVDWNERIKIIYVGDDLTDED 727
            |:....:.....|.:....|:. :.|...:       |....|.|.:|     .|..|.:..||.
 Worm   962 IQAQFARRCAQTCVILTTAPLM-HIGVLDVSTIPNGYYYFGASGGREW-----FIDNGHNFKDES 1020

  Fly   728 AMVALKGMARTFRVTSSDIVKTA---ADHRLPSTDSVYTLLKWV----ERHFMGRKARANSLTYR 785
               .|||       ..:|::.:|   ..|.|...:  :....||    ::|: |....|....|:
 Worm  1021 ---ILKG-------EKADVLASAYTRISHLLEEPE--FRPFTWVGSGLQKHY-GHLTIAFQDVYK 1072

  Fly   786 P-TKGDGVQMQMSLE 799
            . |:..|.|:...:|
 Worm  1073 TITEAQGKQLHEEIE 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	GT1_TPS	19..495	CDD:99963	157/574 (27%)
		PRK14501	20..766	CDD:184712	211/885 (24%)
		HAD_like	530..770	CDD:304363	48/266 (18%)
tps-2	NP_497035.3	trehalose_OtsA	238..787	CDD:274112	156/573 (27%)
		GT1_TPS	238..787	CDD:99963	156/573 (27%)
		HAD-SF-IIB	934..1158	CDD:273651	33/178 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166400
Domainoid	1	1.000	158	1.000	Domainoid score	I2509
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12210
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D76698at33208
OrthoFinder	1	1.000	-	-		FOG0000556
OrthoInspector	1	1.000	-	-		otm14424
orthoMCL	1	0.900	-	-		OOG6_100616
Panther	1	1.100	-	-	O	PTHR10788
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16616
SonicParanoid	1	1.000	-	-		X473
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.830