DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tps1 and CG5177

DIOPT Version :9

Sequence 1:	NP_608827.1	Gene:	Tps1 / 33642	FlyBaseID:	FBgn0027560	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	NP_001260191.1	Gene:	CG5177 / 34017	FlyBaseID:	FBgn0031908	Length:	276	Species:	Drosophila melanogaster

Alignment Length:	263	Identity:	99/263 - (37%)
Similarity:	161/263 - (61%)	Gaps:	6/263 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 DDYLLKYIGY----NHKLALLLDYDGTLAPIAPHPDLATLSPEIKNVLYKLSNHSDVYVAVISGR 578
            :||:....|:    ..::||||||||||||:.  .:|:.:..:.:..:.||:.:..:::.|.|||
  Fly    14 EDYVKALEGFINPETDQVALLLDYDGTLAPLT--EELSVMPKDTEINIKKLAANEKIFMVVFSGR 76

  Fly   579 NVDNVKKMVGIEGITYAGNHGLEILHPDGSKFVHPMPMEYEKKVSDLLKALQDSVCRDGAWVENK 643
            .:..:|..:....:|||||||||:.:|.|.||...||.|..:|.:.|:..|::.|...|||||:|
  Fly    77 ELSEIKNHLKFPNVTYAGNHGLEVEYPSGKKFKIEMPEELLEKHNKLVSELKEKVVCSGAWVEDK 141

  Fly   644 GALLTFHYRETPNHLRGAMVDKARSLIEKYGFKATEAHCALEARPPVQWNKGRASIYILRTSFGV 708
            ...:|:||:...:.|:..::.:|:.||:.:||:..|...|||.:|.|.|:||..:..||...|..
  Fly   142 KISVTYHYKGVTDKLKAKLIAEAKGLIQAHGFQLIETPYALEGKPRVNWDKGEGAKMILEKQFDA 206

  Fly   709 DWNERIKIIYVGDDLTDEDAMVALKGMARTFRVTSSDIVKTAADHRLPSTDSVYTLLKWVERHFM 773
            ||.:.:||:|||||.|||||:..|.|:.:||||:....:||.|::::.:.:.|..|||.|:.::.
  Fly   207 DWAKNLKIVYVGDDTTDEDAIKVLHGIGKTFRVSELPTLKTYANYQIKTVEEVGYLLKAVQAYYE 271

  Fly   774 GRK 776
            .:|
  Fly   272 KKK 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	GT1_TPS	19..495	CDD:99963
		PRK14501	20..766	CDD:184712	95/251 (38%)
		HAD_like	530..770	CDD:304363	95/239 (40%)
CG5177	NP_001260191.1	HAD_like	<5..259	CDD:304363	93/246 (38%)
CG5177	NP_001260191.1	HAD-SF-IIB	32..234	CDD:273651	83/203 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468836
Domainoid	1	1.000	110	1.000	Domainoid score	I2101
eggNOG	1	0.900	-	-		E1_COG1877
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D76698at33208
OrthoFinder	1	1.000	-	-		FOG0000556
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X473
	7	6.750