Protein Alignment Tps1 and tpp1

DIOPT Version :10

• Sequence 1: NP_608827.1
• Gene: Tps1 / 33642
• FlyBaseID: FBgn0027560
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_594430.1
• Gene: tpp1 / 2542577
• PomBaseID: SPAC19G12.15C
• Length: 817
• Species: Schizosaccharomyces pombe
• Alignment Length: 804
• Identity: 201/804 - (25%)
• Similarity: 347/804 - (43%)
• Gaps: 110/804 - (13%)

  Fly    20 LIVVSNRLPFVLIRDPKTDELERRASAGGLVTAVCPVVIKGSGLW----VGWSGI-----HLKDP 75
            :|.|...|||....:.:|.|.:.....|..........:..|..|    |||:|:     ..::.
pombe    39 IIYVLRHLPFKSSINEETREWDLSGRRGATTMYSSMNWLANSTYWQTTLVGWTGVIPTVSEKEEN 103

  Fly    76 NEAIPESNPND-----QTPT---AGLKSEQVVSVNI------------DSKIFDSYYNGCCNKIF 120
            .:|:...:..|     :|.:   :|.:|.:.|.|.:            :::...|.:......:.
pombe   104 KDAVTRLDSQDVKRFEETYSQWNSGERSTEYVPVWLPGPEKGSETIINETRSQQSRWLAYAENVI 168

  Fly   121 WPLFHSMPGRANFGGEH----WHDYVTVNKHFAVRTIEALEKCLAKNQGSEKSPPIVWIHDYHLM 181
            .||.|.....::...|:    |.|||.:|..||.:..|..           |....:.:.||.|.
pombe   169 RPLIHYKYWPSSEVDENEEQWWRDYVKMNHAFADKICEIY-----------KPGDFIIVQDYSLF 222

  Fly   182 LAANWVREHAEEKNLPCRLAFFLHIPFPPWDIFRLLPWSDEILQGMLGCDLVGFHIQDYCLNFVD 246
            |....:|...::    ..:.|:.|.|||..:|.|..|....||:.:||.|.:||....|..:|:.
pombe   223 LVPQLIRNKIDD----AVIGFYHHHPFPSSEIARCFPRRRAILRSVLGADFIGFEDYSYARHFIS 283

  Fly   247 CCQRNLGCRVDRNNLLVEHGGRTVRVRPLPIGIPYERFVNLA---TTAPKVLKTSK----MQIIL 304
            ||.|.|...:..:  .|...|..|.||.:.:||...|.:..:   :.:.|:.:.:|    |::||
pombe   284 CCSRVLDLEIGHD--WVNLNGNKVTVRAITVGIDVPRIIRSSGNVSVSEKLEELNKRYENMKVIL 346

  Fly   305 GVDRLDYTKGLVHRLMAFEALLLKYPQHKEKVSLLQISVPSRTDVKEYRELKEEVDQLVGRINGR 369
            |.||||...|:..:|.:|:..|..||:.::||.|:||::.|   ..::.:|...:.:||..||..
pombe   347 GRDRLDELYGVPQKLRSFQRFLRTYPEWRKKVVLIQITISS---AFKHPKLLSSIKKLVQAINQE 408

  Fly   370 FTTANWAPIRYIYDYVSQDELAALYRDAAVCLVTPLRDGMNLVAKEFVACQINEVPGVLVISPFA 434
            |.|.::.|:.::.:.:...:..||...|....:..:|:|::.:|.|:|.||.:.. |::::|.|.
pombe   409 FGTDDYTPVHHVEEQLEPADYFALLTRADALFINSIREGVSNLALEYVVCQRDRY-GMVLLSEFT 472

  Fly   435 GAGEMMHEALLCNPYEVNEAAEVIHRALTMPEDERVLRMARLRRREAECDVS-----HWMRCFLK 494
            ....|:|:..|.||::.||.||:|..||:.|.:.|     ::..||:...|:     .|....::
pombe   473 ATSAMLHDVPLINPWDYNECAEIISNALSTPLERR-----KMIERESYKQVTTHTMQSWTSSLIR 532

  Fly   495 AVG---ALEMDDVGTTIMQPVSVDDFDDYLLKYIGYNHKLALLLDYDGTLAPIAPHPDLATLSPE 556
            ::.   |....|.....:.|       ::.|.......|...::||||||.||...|:.|..|.:
pombe   533 SLANKLAATKTDQRIPTLTP-------EHALSVYSKASKRLFMMDYDGTLTPIVRDPNAAVPSKK 590

  Fly   557 IKNVLYKLSNHSDVYVAVISGRNVDNVKK-MVGIEGITYAGNHGLEILHPDGSKFVH---PMPME 617
            :.:.|..|:......|.:||||:...::. |..|:|:..:..||..:..|..:.:::   .:.|.
pombe   591 LLDNLATLAADPKNQVWIISGRDQQFLRNWMDDIKGLGLSAEHGSFVRKPHSTTWINLAELLDMS 655

  Fly   618 YEKKVSDLLKALQDSVCRDGAWVENKGALLTFHYRETPNHLRGAMVDKARSLIE-----KYGFKA 677
            ::|:|..:.:...|..  .|:.:|.|...:|:|||:...........:..:|:|     ||..:.
pombe   656 WKKEVRRIFQYYTDRT--QGSSIEEKRCAMTWHYRKADPENGAFQALECEALLEELVCSKYDVEI 718

  Fly   678 TEAHCALEARPPVQWNKGRASIYILRT-------SFGVDWNERIKIIYVGDDLTDEDAMVALKGM 735
            ......||.||. ..|||.....||.:       ||         |...|||.||||...:|...
pombe   719 MRGKANLEVRPS-SINKGGIVKQILSSYPEDSLPSF---------IFCAGDDRTDEDMFRSLHKN 773

  Fly   736 ARTFRVTSSDIVKTAADHRLPSTD 759
            .|..:.||. .|...:|.:|...|
pombe   774 TRINKETSF-AVTIGSDKKLSIAD 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tps1	NP_608827.1	PRK14501	20..766	CDD:184712	201/804 (25%)
tpp1	NP_594430.1	Glyco_transf_20	31..536	CDD:425972	130/522 (25%)
		Trehalose_PPase	568..802	CDD:426737	66/242 (27%)