Protein Alignment Vps53 and vps53

DIOPT Version :9

• Sequence 1: NP_608825.2
• Gene: Vps53 / 33640
• FlyBaseID: FBgn0031598
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: XP_002934389.2
• Gene: vps53 / 100496110
• XenbaseID: XB-GENE-1011610
• Length: 830
• Species: Xenopus tropicalis
• Alignment Length: 915
• Identity: 435/915 - (47%)
• Similarity: 577/915 - (63%)
• Gaps: 116/915 - (12%)

  Fly     1 MSESAVAVEPEERMVANNKIHFSKEVKQVIDKVLKTDDPMDAPDFNTVDYINQLFPNEQSLAGID 65
            |.|..:.|..|...|    :|.|.||:|.|::|..:.||:|..|||.|:|||.|||.||||:.||
 Frog     1 MDEEELEVVEELEAV----LHLSPEVQQAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLSNID 61

  Fly    66 ETIQKMQCEVSLIDDNIRSVVRGQTNTGQDGQLALCEAQKVISSLFSHIIDVKTRAERTEEMVKE 130
            :.:.|::.::..:|||||:|||||||.||||:.||.||||.|..||..|.|:|.:||::|:||||
 Frog    62 DVVSKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKE 126

  Fly   131 ITRDIKQLDCAKRNLTAAITTLNHLHMLVGGIESLNKLIERRSYGEILNPLQAITEVNQHFQQFS 195
            |||||||||.|||:||.:||||||||||.||::||..:..:|.|||:.|.||.:..|.:|||::.
 Frog   127 ITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRKRQYGEVANLLQGVVNVLEHFQKYM 191

  Fly   196 DIEEIKNLSQSVDKIQVTLAQQITEDFKEAFSAKPSSQNQHRLG--LNQLADACKVMSVLDPKVK 258
            .|.:|:.||:.|...|..|.|||..||:|:|    .||...|.|  .|.|.|||.|.:|||.::|
 Frog   192 GIPQIRQLSERVKAAQTELGQQILADFEESF----PSQGTKRPGGPSNVLRDACLVANVLDSRIK 252

  Fly   259 KELLKWFIAQQLEEYTHLFHENQDIAWLDKIDKRYAWLKRHLLDFEDKYGPVFPLDWEVSERITV 323
            :|::|.||.|.|.||:.||.||||:|||||||:||||:||.|:|:|:|||.:||:||.::|||.|
 Frog   253 QEIIKKFIRQHLSEYSVLFQENQDVAWLDKIDRRYAWIKRQLVDYEEKYGRMFPVDWCMTERIAV 317

  Fly   324 EFCRQTREQLAQIMAKRTNEIDVRLLLFAINKTQAFEQLLSKRFTGVTLG----AQPTDKARVLA 384
            |||..||..|::||..|..||:|:||||||.:|..||.||:|||:|.||.    .:|..:..|..
 Frog   318 EFCHITRNDLSKIMRTRAKEIEVKLLLFAIQRTTNFEGLLAKRFSGSTLSDNVVKKPDPQPPVST 382

  Fly   385 EP-----TTTDGAV---------------GLTVFHDQIGQCFKPHLDIYIRSIDRNLSELMDKFV 429
            .|     ..||.:|               ....||..|.:||:|||.:||.|.|:|||||:|:||
 Frog   383 NPFLDDDNLTDESVLDKDSDLDKPKKPKLPENPFHGIISKCFEPHLYVYIESQDKNLSELIDRFV 447

  Fly   430 ---EMSREPYKFAEAKTTVYPSSGDLFVFYKKCMVQCNQLSNEQPMYDLALVFKKYLREYASKVL 491
               :....|...:|....|.||..||||:||||||||:|||..:||..|:.:|:|||||||.|:|
 Frog   448 GDFKAQGPPKSTSEDAGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALSTIFQKYLREYAWKIL 512

  Fly   492 EGSTPKLVPATTSSSIGKSVSLLTRDMQNLSTAAGQVFHNFLKEG-DTQRFARDDLVRICCVLTT 555
            .|:.||    |:|||.|.:::.|.::                ||| :..:|..::|..||.:|:|
 Frog   513 SGNLPK----TSSSSSGLTITSLLKE----------------KEGSEVAKFTPEELCLICSILST 557

  Fly   556 GEYCLETVQQLEDKLKEKVTSAYVSKIDMSEEKDVFHRIISNCIQLLVQDLEAGCEASLQAMAKV 620
            .||||.|.||||:||||||......:|:::.|.|.|..:|||.||||||||::.|:.:|.||:|:
 Frog   558 AEYCLATTQQLEEKLKEKVDLTLTERINLTGEMDTFSTVISNSIQLLVQDLDSSCDPALIAMSKM 622

  Fly   621 QWQHINNVGDQSAFISSLCGNFKQTVPTIRDTLASSRKYFTQFCHRFVAAFIPKFINVLYRCKLT 685
            |||::.:|||||.:::|:..:.||:||.|||.|||:||||||||.:|..:|||||||.|::||
 Frog   623 QWQNVEHVGDQSPYVTSIIFHIKQSVPIIRDNLASTRKYFTQFCIKFANSFIPKFINHLFKCK-- 685

  Fly   686 LSDGSNNVLGCEQLLLDTHSLKTALLELPSVGSSVNRKAPTSYTKVVVKDMTRAEMIIKVVMTPV 750
                ..:::|.||||||||||||.||:|||:||.|.||||.||||:|||.|||||||:||||.|.
 Frog   686 ----PISMVGAEQLLLDTHSLKTVLLDLPSIGSQVIRKAPASYTKIVVKGMTRAEMILKVVMAPH 746

  Fly   751 QPPAHFTQQVLKLLPDITIAEYQKILDMKAVKRVDQLQLIDLFKHTASAAAVSGLIEPTTGEEET 815
            :|...|....:|||.|.|...:||||:||.:||.:|..::|||:....|        |.:|.|.:
 Frog   747 EPSVVFVDNYIKLLADCTTETFQKILEMKGLKRSEQSTMLDLFRQRLPA--------PPSGSENS 803

  Fly   816 QGAETVVATSGTTDDAETSAVPTETTTATSSTPKRAFIFSVGSFTGSADKNADGSSQTGIRKLEN 880
                             ::|:|..|....||.                           |||||.
 Frog   804 -----------------SAALPAPTPEQESSR---------------------------IRKLEK 824

  Fly   881 LLKKR 885
            |:|||
 Frog   825 LIKKR 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps53	NP_608825.2	Vps53_N	42..434	CDD:282020	215/420 (51%)
vps53	XP_002934389.2	Vps53_N	38..452	CDD:282020	215/417 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	406	1.000	Domainoid score	I701
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6264
Inparanoid	1	1.050	775	1.000	Inparanoid score	I525
OMA	1	1.010	-	-		QHG54046
OrthoDB	1	1.010	-	-		D1379600at2759
OrthoFinder	1	1.000	-	-		FOG0004449
OrthoInspector	1	1.000	-	-		oto105353
Panther	1	1.100	-	-	LDO	PTHR12820
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1657
SonicParanoid	1	1.000	-	-		X4236
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110