DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17612 and STP3

DIOPT Version :9

Sequence 1:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_013479.3	Gene:	STP3 / 851089	SGDID:	S000004367	Length:	343	Species:	Saccharomyces cerevisiae

Alignment Length:	222	Identity:	50/222 - (22%)
Similarity:	90/222 - (40%)	Gaps:	39/222 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 AHIRTHNETRTTEPPRLK-CPMCPSIYMKRGCLEAHMWIHRASDERESELEPPYRCPHCPKLFLY 368
            |.:.|.:.|:..:|.:.| ||:|.:.|..   |..|...|...::|      |::||.|.:.|..
Yeast   125 AGVSTPHSTKINKPRKKKQCPICRNFYAN---LTTHKATHLTPEDR------PHKCPICHRGFAR 180

  Fly   369 SSFLEIHIQTH--EDVSQRLSRKSSHKCAQCADV----------FSDVSSLKDHVK---IHAGER 418
            ::.|..|.:.|  :::..:....|:|...:...|          .:.::|:.|:.:   :|..:.
Yeast   181 NNDLLRHKKRHWKDEILSQSGVLSNHNDGKGGSVSPNDDDTHEKMTPMNSVTDYAQLKSLHQIKG 245

  Fly   419 TFKCPLCLMSFQEESNLKSHDCAHTRFK---CH------KCSKFFESQNYLDFHF----KKSHTT 470
            |||||......|.:.::..:......|:   ||      :|..|......|.|.:    ||....
Yeast   246 TFKCPFNSTLIQLDMDMYPYKLKPLNFETSNCHQTGVFSRCDTFKNHLKALHFEYPPGTKKKDRN 310

  Fly   471 KGPFKCIKCQQTFQKRN-GLKEHISSQ 496
            ..|.:|..|...|:..: .|.||:..|
Yeast   311 VVPGRCKHCGLKFENVDVWLNEHVGKQ 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071
		C2H2 Zn finger	290..310	CDD:275368	1/4 (25%)
		C2H2 Zn finger	323..343	CDD:275370	6/19 (32%)
		zf-C2H2_8	356..438	CDD:292531	20/96 (21%)
		C2H2 Zn finger	359..379	CDD:275368	6/19 (32%)
		C2H2 Zn finger	394..414	CDD:275368	3/32 (9%)
		C2H2 Zn finger	422..438	CDD:275368	3/15 (20%)
		C2H2 Zn finger	447..463	CDD:275368	5/21 (24%)
		C2H2 Zn finger	476..505	CDD:275368	7/22 (32%)
		C2H2 Zn finger	513..533	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	568..584	CDD:275368
STP3	NP_013479.3	COG5048	<137..295	CDD:227381	35/166 (21%)
		C2H2 Zn finger	144..161	CDD:275368	6/19 (32%)
		C2H2 Zn finger	171..191	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100