DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17612 and pita

DIOPT Version :9

Sequence 1:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_611806.3	Gene:	pita / 37730	FlyBaseID:	FBgn0034878	Length:	683	Species:	Drosophila melanogaster

Alignment Length:	603	Identity:	130/603 - (21%)
Similarity:	207/603 - (34%)	Gaps:	151/603 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSVKRGGSLPKTLCLQC--LHMDTFGTKHKGPRPETQINDKVHLEMSINGEDGLP-EHPLYPEVQ 75
            :.|..|..:|..:||:|  |....:..|....|.||.:.     :..:.|....| |.|..|...
  Fly    53 IEVYAGDGMPGHICLECRLLFEHCYRFKQMCKRAETLLR-----QYPLTGNWPSPLEKPRAPMTM 112

  Fly    76 LVVKEEDALIKKKVIEENHIHNEEIIGASNIVDVEVHENHRANNDVILIQDSFAEEVILEDHPAN 140
            :.        .||::               :|..:..|.......::......:.:||:||....
  Fly   113 VA--------SKKLL---------------VVPAKTAEPSETPKKLLNTMAKSSSQVIIEDVQVL 154

  Fly   141 NDVIIIQDSVAEE----------ELPVIKEEAIEGEDLQGEYFIITECLEEPAIGSCRVCLEQSD 195
            ...::...:||..          ||.|...:.:..:|:|       ..||:.|           .
  Fly   155 ESAMVTPRTVAGSSPVPRRSHAYELKVDNNQELSMDDVQ-------SMLEDMA-----------S 201

  Fly   196 NLTNIFDDAHQYGIPI---------ATILSQYTGMPVE---------KGDSFSEYICVTCLDVVK 242
            .|...|.|..|...|:         ..||::....|||         :.||.:..|....||
  Fly   202 ELEKEFPDIPQKASPVKPKVLNKSSIRILNKGPAAPVEPRLATPKVKRDDSGNVAIVTEVLD--- 263

  Fly   243 NAFDDLESKENTIQMYRQPKEEIIDIDSIPVKNKPVDYEVTGKPPHRCPQCPKIFLLAAKLQAHI 307
               .||.                :|....|.||.    |........||.|.:.|.|...|:.|.
  Fly   264 ---SDLP----------------LDDQDDPTKNA----EKVATDVFPCPDCERSFPLQQLLEIHR 305

  Fly   308 RTHNETRTTEPPRLKCPMCPSIYMKRGCLEAHMWIHRASDERESELEPPYRCPHCPKLFLYSSFL 372
            ..|..:|:     .:|.:|...:..:..|..|.::|..        |.|::|..|.|.|...:.|
  Fly   306 LNHTRSRS-----FQCLLCEKSFFSKYDLAKHNFVHTG--------ERPFKCAICSKAFTRKALL 357

  Fly   373 EIHIQTHEDVSQRLSRKSSHKCAQCADVFSDVSSLKDHVKIHAGERTFKCPLCLMSFQEESNLKS 437
            ..|.:||.||.:.:       |..|...|.....::.|.:.|..:|.|:|.:|..||..:..|:.
  Fly   358 HRHERTHTDVPKFI-------CVYCEKPFLSRQEMEKHAERHQKKRPFQCGVCTKSFAFKQGLER 415

  Fly   438 HDCAHTR---FKCHKCSKFFESQNYLDFHFKKSHTTKGPFKCIKCQQTFQKRNGLKEHI------ 493
            |:..|:.   |.|..|.:.|.:.:.|..|. .:|..|..:.|..|.:::...:.|..|:
  Fly   416 HETVHSTNLPFPCQHCERSFSTASKLARHL-VAHAGKRAYPCKYCHKSYMLSHHLSRHLRTHTQT 479

  Fly   494 --SSQVCVQFLRSKS------------PGQIFPCPKCPKKFSIEDNYQMHHATHKKVKTVIERHN 544
              :|.||.:...|.|            ......||.|.|:....|:.:.|...||:    .|||.
  Fly   480 SDASFVCSECKVSYSNYNDLLDHALIHATASLKCPMCRKQIEDIDSVESHMDQHKQ----SERHA 540

  Fly   545 CTQCKKSYQNKKLLTKHI 562
            |..|...:..:|.|.:||
  Fly   541 CEFCDHIFLTQKCLQRHI 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071	15/76 (20%)
		C2H2 Zn finger	290..310	CDD:275368	7/19 (37%)
		C2H2 Zn finger	323..343	CDD:275370	4/19 (21%)
		zf-C2H2_8	356..438	CDD:292531	23/81 (28%)
		C2H2 Zn finger	359..379	CDD:275368	6/19 (32%)
		C2H2 Zn finger	394..414	CDD:275368	4/19 (21%)
		C2H2 Zn finger	422..438	CDD:275368	5/15 (33%)
		C2H2 Zn finger	447..463	CDD:275368	4/15 (27%)
		C2H2 Zn finger	476..505	CDD:275368	7/36 (19%)
		C2H2 Zn finger	513..533	CDD:275368	6/19 (32%)
		C2H2 Zn finger	545..565	CDD:275368	6/18 (33%)
		C2H2 Zn finger	568..584	CDD:275368
pita	NP_611806.3	zf-AD	17..92	CDD:214871	11/43 (26%)
		COG5048	<281..506	CDD:227381	57/245 (23%)
		C2H2 Zn finger	288..308	CDD:275368	7/19 (37%)
		C2H2 Zn finger	316..336	CDD:275368	4/19 (21%)
		zf-H2C2_2	328..353	CDD:290200	9/32 (28%)
		C2H2 Zn finger	344..364	CDD:275368	6/19 (32%)
		C2H2 Zn finger	372..388	CDD:275370	3/15 (20%)
		C2H2 Zn finger	400..420	CDD:275368	6/19 (32%)
		C2H2 Zn finger	428..448	CDD:275368	5/20 (25%)
		C2H2 Zn finger	456..476	CDD:275368	4/19 (21%)
		C2H2 Zn finger	486..506	CDD:275368	3/19 (16%)
		HARE-HTH	<566..625	CDD:294801
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449789
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I3381
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.080