DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17612 and crol

DIOPT Version :9

Sequence 1:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	120/494 - (24%)
Similarity:	188/494 - (38%)	Gaps:	136/494 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 CRVC---LEQSDNLTNIFDDAHQYGIPIATILSQYTGMPVEKGDSFSEYICVTCLDVVKNAFDDL 248
            |:||   ...|.:||       ::|       ..:.|.|:        :.|:.|.:|..|
  Fly   251 CQVCGQGFTTSQDLT-------RHG-------KIHIGGPM--------FTCIVCFNVFAN----- 288

  Fly   249 ESKENTIQMYRQPKEEIIDIDSIPVKNKPVDYEV------------------TGKPPHRCPQCPK 295
                || .:.|..|....|        ||....:                  ||:.|.||..|.|
  Fly   289 ----NT-SLERHMKRHSTD--------KPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAK 340

  Fly   296 IFLLAAKLQAHIRTHNETRTTEPPRLKCPMC-PSIYMKRGCLEAHMW------------------ 341
            .|.....:..|:|.|    |.|.|. :|.:| .|...|...:..:||
  Fly   341 TFTRKEHMVNHVRKH----TGETPH-RCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTR 400

  Fly   342 -IHRASDERESELEPPYRCPHCPKLFLYSSFLEIHIQTHEDVSQRLSRKSSHKCAQCADVFSDVS 405
             .|.|:..|....|.|:||..|.|.|........||..|       :.::.|:|..|:..|:...
  Fly   401 KEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWH-------TGETPHRCDFCSKTFTRKE 458

  Fly   406 SLKDHVKIHAGERTFKCPLCLMSFQEESNLKSHDCAH---TRFKCHKCSKFFESQNYLDFHFKKS 467
            .|.:||:.|.||...:|..|:.:|..:.:|.:|...|   |.|||..|:|.|..::::..|.::
  Fly   459 HLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQ- 522

  Fly   468 HTTKGPFKCIKCQQTFQKRNGLKEHISSQVCVQFLRSKSPGQIFPCPKCPKKFSIEDNYQMHHAT 532
            ||.:.|.||..|.:||.:    |||:::.|     |..:......|..|.|.|:.::    |...
  Fly   523 HTGESPHKCTYCTKTFTR----KEHLTNHV-----RQHTGDSPHRCSYCKKTFTRKE----HLTN 574

  Fly   533 HKKVKTVIERHNCTQCKKSYQNKKLLTKHILSHNR-----CVHCSMSFTSKYLLEQH-------- 584
            |.::.|....|.|..|:|::..|:.|..|:..|:.     |..|:..||.|..|..|
  Fly   575 HVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGD 639

  Fly   585 ------TCSQSYQLNGSRGRKNPNLNYNECEESNESDLE 617
                  ||.:|:.|.|       ||.:::...:...::|
  Fly   640 RPFTCETCGKSFPLKG-------NLLFHQRSHTKGQEME 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071	13/61 (21%)
		C2H2 Zn finger	290..310	CDD:275368	6/19 (32%)
		C2H2 Zn finger	323..343	CDD:275370	6/39 (15%)
		zf-C2H2_8	356..438	CDD:292531	23/81 (28%)
		C2H2 Zn finger	359..379	CDD:275368	6/19 (32%)
		C2H2 Zn finger	394..414	CDD:275368	6/19 (32%)
		C2H2 Zn finger	422..438	CDD:275368	4/15 (27%)
		C2H2 Zn finger	447..463	CDD:275368	4/15 (27%)
		C2H2 Zn finger	476..505	CDD:275368	9/28 (32%)
		C2H2 Zn finger	513..533	CDD:275368	5/19 (26%)
		C2H2 Zn finger	545..565	CDD:275368	6/19 (32%)
		C2H2 Zn finger	568..584	CDD:275368	6/15 (40%)
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368	7/33 (21%)
		C2H2 Zn finger	279..299	CDD:275368	8/29 (28%)
		COG5048	300..723	CDD:227381	103/413 (25%)
		C2H2 Zn finger	307..327	CDD:275368	0/19 (0%)
		C2H2 Zn finger	335..355	CDD:275368	6/19 (32%)
		C2H2 Zn finger	363..383	CDD:275368	5/19 (26%)
		C2H2 Zn finger	391..411	CDD:275368	3/19 (16%)
		C2H2 Zn finger	419..439	CDD:275368	6/19 (32%)
		C2H2 Zn finger	447..467	CDD:275368	6/19 (32%)
		C2H2 Zn finger	475..495	CDD:275368	5/19 (26%)
		C2H2 Zn finger	503..523	CDD:275368	5/20 (25%)
		C2H2 Zn finger	531..551	CDD:275368	9/28 (32%)
		C2H2 Zn finger	559..579	CDD:275368	6/23 (26%)
		C2H2 Zn finger	587..607	CDD:275368	6/19 (32%)
		C2H2 Zn finger	615..636	CDD:275368	7/20 (35%)
		C2H2 Zn finger	644..664	CDD:275368	7/26 (27%)
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..722	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446695
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930